Howard Zalkin

Overview

Best Publications

• Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices

  Maria A. Schumacher;Kang Yell Choi;Howard Zalkin;Richard G. Brennan

  513
  Citations

• Enzymes Utilizing Glutamine as an Amide Donor

  Howard Zalkin;Janet L. Smith

  355
  Citations

• Cloning and characterization of a 12-gene cluster from Bacillus subtilis encoding nine enzymes for de novo purine nucleotide synthesis.

  D J Ebbole;H Zalkin

  333
  Citations

• Structure of the allosteric regulatory enzyme of purine biosynthesis

  Janet L. Smith;Eugene J. Zaluzec;Eugene J. Zaluzec;Jean Pierre Wery;Jean Pierre Wery;Liwen Niu;Liwen Niu

  321
  Citations

• Coupled Formation of an Amidotransferase Interdomain Ammonia Channel and a Phosphoribosyltransferase Active Site

  Joseph M. Krahn;Jeong Hyun Kim;Mark R. Burns;Ronald J. Parry

  262
  Citations

• De novo purine nucleotide biosynthesis.

  Howard Zalkin;Jack E. Dixon

  204
  Citations

• Escherichia coli gene purR encoding a repressor protein for purine nucleotide synthesis: cloning, nucleotide sequence, and interaction with the purF operator

  R J Rolfes;H Zalkin

  190
  Citations

• A mutation in adenylosuccinate lyase associated with mental retardation and autistic features.

  Randy L. Stone;Junko Aimi;Bruce A. Barshop;Jaak Jaeken

  165
  Citations

• The Anthranilate Synthetase-Anthranilate-5-Phosphoribosylpyrophosphate Phosphoribosyltransferase Aggregate ON THE REACTION MECHANISM OF ANTHRANILATE SYNTHETASE FROM SALMONELLA TYPHIMURIUM

  H. Nagano;H. Zalkin;Ellen J. Henderson

  155
  Citations

• A cysteine-histidine-aspartate catalytic triad is involved in glutamine amide transfer function in purF-type glutamine amidotransferases.

  Baigen Mei;H. Zalkin

  138
  Citations

• Nucleotide sequence of Escherichia coli pyrG encoding CTP synthetase.

  M Weng;C A Makaroff;H Zalkin

  137
  Citations

• Identification of the Bacillus subtilis pur operon repressor

  Manli Weng;Peter L. Nagy;Howard Zalkin

  136
  Citations

• Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli

  Christine R.A. Muchmore;Joseph M. Krahn;Jeong Hyun Kim;Jeong Hyun Kim;Howard Zalkin

  134
  Citations

• Mechanism of corepressor-mediated specific DNA binding by the purine repressor

  Maria A. Schumacher;Kang Yell Choi;Fu Lu;Howard Zalkin

  131
  Citations

• Regulated in Vitro Synthesis of Escherichia coli Tryptophan Operon Messenger Ribonucleic Acid and Enzymes

  Howard Zalkin;Charles Yanofsky;Catherine L. Squires

  127
  Citations

• Structure and function of the glutamine phosphoribosylpyrophosphate amidotransferase glutamine site and communication with the phosphoribosylpyrophosphate site.

  Jeong Hyun Kim;Joseph M. Krahn;Diana R. Tomchick;Janet L. Smith

  119
  Citations

• De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementation in E. coli.

  Junko Aimi;Hong Qiu;John Williams;Howard Zalkin

  112
  Citations

• Cloning of the Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase gene in Escherichia coli. Nucleotide sequence determination and properties of the plasmid-encoded enzyme.

  C A Makaroff;H Zalkin;R L Switzer;S J Vollmer

  111
  Citations

• Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family

  Sangita Sinha;Pekka Rappu;S. C. Lange;Pekka Mäntsälä

  108
  Citations

• Binding of cytosolic aconitase to the iron responsive element of porcine mitochondrial aconitase mRNA

  Limin Zheng;Mary Claire Kennedy;George A. Blondin;Helmut Beinert

  98
  Citations