World's Best Scientists 2026 revealed!
Holger Wigström

Holger Wigström

D-Index & Metrics

Neuroscience

D-Index
31
Citations
5471
World Ranking
9567
National Ranking
176

Research.com Recognitions

  • 1989 - W. Alden Spencer Award, College of Physicians and Surgeons

Overview

Holger Wigström is affiliated with the University of Gothenburg in Sweden and works primarily within the field of Neuroscience. Their research spans various subfields including Biological Psychiatry, Behavioral Neuroscience, Social Psychology, Cellular and Molecular Neuroscience, and Biochemistry.

Their recent publications demonstrate a focus on mechanisms related to brain function and neuropharmacology, with particular attention to tryptophan metabolism and neuroendocrine regulation. Notable papers include:

  • Blockade of KAT II Facilitates LTP in Kynurenine 3-Monooxygenase Depleted Mice, 2021, International Journal of Tryptophan Research
  • How do NMDA and AMPA receptors share a common regulatory mechanism that underlies the NMDAR-dependent LTP and LTD?, 2024, Research Square (Research Square)

Frequent co-authors in their work are:

  • Sophie Imbeault
  • Max Gubert Olivé
  • Oscar Jungholm
  • Sophie Erhardt
  • Göran Engberg

The venues where Holger Wigström's research has been published include:

  • International Journal of Tryptophan Research
  • Research Square (Research Square)

The main topics explored in their research are:

  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Neuroendocrine regulation and behavior
  • Neuroscience and Neuropharmacology Research
  • Amino Acid Enzymes and Metabolism

In 1989, Holger Wigström received the W. Alden Spencer Award from the College of Physicians and Surgeons.

Best Publications

  • Possible mechanisms for long-lasting potentiation of synaptic transmission in hippocampal slices from guinea-pigs.

    P Andersen;S H Sundberg;O Sveen;J W Swann

  • On the function of recurrent inhibition in the spinal cord.

    H Hultborn;S Lindström;H Wigström

  • Facilitated induction of hippocampal long-lasting potentiation during blockade of inhibition

    Unknown

  • A transient outward current in a mammalian central neurone blocked by 4-aminopyridine

    B. Gustafsson;Martin Galvan;Peter Grafe;H. Wigström

  • Hippocampal long‐term potentiation is induced by pairing single afferent volleys with intracellular^ injected depolarizing current pulses

    H. Wigström;B. Gustafsson;Y.-Y. Huang;W. C. Abraham

  • Maintained changes in motoneuronal excitability by short-lasting synaptic inputs in the decerebrate cat.

    C Crone;H Hultborn;O Kiehn;L Mazieres

  • Physiological mechanisms underlying long-term potentiation

    Unknown

  • Long‐term potentiation involves enhanced synaptic excitation relative to synaptic inhibition in guinea‐pig hippocampus.

    W C Abraham;B Gustafsson;H Wigström

  • Facilitation of hippocampal long-lasting potentiation by GABA antagonists.

    Unknown

  • The Relative Contribution of NMDA Receptor Channels in the Expression of Long-term Potentiation in the Hippocampal CA1 Region.

    Fredrik Asztely;Holger Wigström;Bengt Gustafsson

  • On long-lasting potentiation in the hippocampus: a proposed mechanism for its dependence on coincident pre- and postsynaptic activity.

    Unknown

  • Onset Characteristics of Long-Term Potentiation in the Guinea-Pig Hippocampal CA1 Region in Vitro

    B. Gustafsson;F. Asztely;E. Hanse;H. Wigström

  • Calcium dependency of synaptic long-lasting potentiation in the hippocampal slice.

    H. Wigström;J. W. Swann;P. Andersen

  • A possible correlate of the postsynaptic condition for long-lasting potentiation in the guinea pig hippocampus in vitro

    Unknown

  • Large long-lasting potentiation in the dentate gyrus in vitro during blockade of inhibition

    Unknown

  • Phorbol ester-induced synaptic potentiation differs from long-term potentiation in the guinea pig hippocampus in vitro.

    Bengt Gustafsson;Yan-You Huang;Holger Wigström

  • Role of NMDA receptor subtypes in different forms of NMDA-dependent synaptic plasticity.

    Rui Li;Fen-Sheng Huang;Abdul-Karim Abbas;Holger Wigström

  • Long-term potentiation in the hippocampal CA1 region : its induction and early temporal development

    Bengt Gustafsson;Holger Wigström

  • Mode of action of excitatory amino acid receptor antagonists on hippocampal long-lasting potentiation

    Unknown

  • Recurrent inhibition and afterhyperpolarization following motoneuronal discharge in the cat.

    H Hultborn;E Pierrot-Deseilligny;H Wigström

  • On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region of young rats

    Min-Yi Xiao;M. Karpefors;B. Gustafsson;H. Wigstrom

  • Distribution of recurrent inhibition within a motor nucleus. I. Contribution from slow and fast motor units to the excitation of Renshaw cells

    Hultborn H;Lipski J;Mackel R;Wigström H

  • Persistent LTP without triggered protein synthesis.

    Abdul-Karim Abbas;Mikhail Dozmorov;Rui Li;Fen-Sheng Huang

  • Activity‐dependent Decay of Early LTP Revealed by Dual EPSP Recording in Hippocampal Slices from Young Rats

    Min‐Yi Xiao;Yin‐Ping Niu;Holger Wigström

  • Single high strength afferent volleys can produce long-term potentiation in the hippocampus in vitro

    W.C. Abraham;B. Gustafsson;H. Wigström

  • Synaptic potentiation in the hippocampal CA1 region induced by application of N-methyl-D-aspartate.

    F. Asztely;E. Hanse;H. Wigström;B. Gustafsson

  • Characterization of NMDA induced depression in rat hippocampus: involvement of AMPA and NMDA receptors.

    Rui Li;Mikhail Dozmorov;Fredrik Hellberg;Ye Tian

Frequent Co-Authors

Eric Hanse
Eric Hanse University of Gothenburg
Abdul H. Mohammed
Abdul H. Mohammed Linnaeus University

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