Hans W. Kosterlitz

Research.com Recognitions

• 1985 - Member of the National Academy of Sciences
• 1982 - GlaxoSmithKline Prize, Royal Society of London in recognition of his studies of the action of opiates and the discovery of the enkephalins
• 1978 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

Overview

Best Publications

• Identification of two related pentapeptides from the brain with potent opiate agonist activity

  J. Hughes;T. W. Smith;H. W. Kosterlitz;Linda A. Fothergill

  5221
  Citations

• Endogenous opioid peptides: multiple agonists and receptors

  John A. H. Lord;Angela A. Waterfield;John Hughes;Hans W. Kosterlitz

  3759
  Citations

• Classification of opioid receptors.

  S J Paterson;L E Robson;H W Kosterlitz

  1152
  Citations

• THE BINDING SPECTRUM OF NARCOTIC ANALGESIC DRUGS WITH DIFFERENT AGONIST AND ANTAGONIST PROPERTIES

  Jacques Magnan;Stewart J. Paterson;Alessandra Tavani;Hans W. Kosterlitz

  736
  Citations

• Dynorphin 1-8 and dynorphin 1-9 are ligands for the κ-subtype of opiate receptor

  Alistair D. Corbett;Stewart J. Paterson;Alexander T. McKnight;Jacques Magnan

  644
  Citations

• CHARACTERIZATION OF THE k-SUBTYPE OF THE OPIATE RECEPTOR IN THE GUINEA-PIG BRAIN

  H.W. Kosterlitz;S.J. Paterson;L.E. Robson

  587
  Citations

• EFFECT OF MORPHINE ON ADRENERGIC TRANSMISSION IN THE MOUSE VAS DEFERENS. ASSESSMENT OF AGONIST AND ANTAGONIST POTENCIES OF NARCOTIC ANALGESICS

  J. Hughes;H.W. Kosterlitz;Frances M. Leslie

  520
  Citations

• The effects of adrenaline, noradrenaline and isoprenaline on inhibitory α- and β-adrenoceptors in the longitudinal muscle of the guinea-pig ileum

  H. W. Kosterlitz;R. J. Lydon;A. J. Watt

  509
  Citations

• KINETIC PARAMETERS OF NARCOTIC AGONISTS AND ANTAGONISTS, WITH PARTICULAR REFERENCE TO N‐ALLYLNOROXYMORPHONE (NALOXONE)

  H. W. Kosterlitz;A. J. Watt

  496
  Citations

• Effects of changes in the structure of enkephalins and of narcotic analgesic drugs on their interactions with μ and δ-receptors

  H.W. Kosterlitz;J.A.H. Lord;S.J. Paterson;Angela A. Waterfield

  443
  Citations

• Spectrum of the μ-, δ- and κ-binding sites in homogenates of rat brain

  M.G.C. Gillan;H.W. Kosterlitz

  394
  Citations

• Some thoughts on the significance of enkephalin, the endogenous ligand

  Hans W. Kosterlitz;John Hughes

  381
  Citations

• In vitro pharmacology of the opioid peptides, enkephalins and endorphins

  Angela A. Waterfield;Roger W.J. Smokcum;John Hughes;Hans W. Kosterlitz

  276
  Citations

• Selectivities of opioid peptide analogues as agonists and antagonists at the δ‐receptor

  A.D. Corbett;M.G.C. Gillan;H.W. Kosterlitz;A.T. McKnight

  244
  Citations

• In vitro release of Leu- and Met-enkephalin from the corpus striatum.

  G. Henderson;G. Henderson;J. Hughes;J. Hughes;H. W. Kosterlitz

  228
  Citations

• ASSESSMENT IN THE GUINEA-PIG ILEUM AND MOUSE VAS DEFERENS OF BENZOMORPHANS WHICH HAVE STRONG ANTINOCICEPTIVE ACTIVITY BUT DO NOT SUBSTITUTE FOR MORPHINE IN THE DEPENDENT MONKEY

  M. Hutchinson;H.W. Kosterlitz;Frances M. Leslie;Angela A. Waterfield

  214
  Citations

• Characterization of opioid receptors in nervous tissue.

  Hans Walter Kosterlitz;S. J. Paterson

  207
  Citations

• Comparison of the binding characteristics of tritiated opiates and opioid peptides.

  Maureen G.C. Gillan;H.W. Kosterlitz;S.J. Paterson

  204
  Citations

• Increase in potencies of opioid peptides after peptidase inhibition.

  Alexander T. Mcknight;Alistair D. Corbett;Hans W. Kosterlitz

  199
  Citations

• Specific Protection of the Binding Sites of D-Ala$^{2}$-D-Leu$^{5}$-enkephalin ($\delta $-receptors) and Dihydromorphine ($\mu $-Receptors)

  Linda E. Robson;Hans Walter Kosterlitz

  168
  Citations