H. Fred Clark

Overview

Best Publications

• Safety and Efficacy of a Pentavalent Human–Bovine (WC3) Reassortant Rotavirus Vaccine

  Timo Vesikari;David O Matson;Penelope Dennehy;Pierre Van Damme

  2340
  Citations

• Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens.

  V. Gouvea;R. I. Glass;P. Woods;K. Taniguchi

  2017
  Citations

• Pathogenic mycoplasmas: cultivation and vertebrate pathogenicity of a new spiroplasma

  JG Tully;RF Whitcomb;HF Clark;DL Williamson

  563
  Citations

• A DIALYSIS TECHNIQUE FOR PREPARING FLUORESCENT ANTIBODY.

  H Fred Clark;Charles C. Shepard

  562
  Citations

• Rotavirus isolate WI61 representing a presumptive new human serotype.

  H F Clark;Y Hoshino;L M Bell;J Groff

  307
  Citations

• Molecular basis of rotavirus virulence: role of gene segment 4.

  P A Offit;G Blavat;H B Greenberg;H F Clark

  294
  Citations

• Group A rotaviruses produce extrahepatic biliary obstruction in orally inoculated newborn mice.

  Marie Riepenhoff-talty;Marie Riepenhoff-talty;Knut Schaekel;H Fred Clark;Wolfgang Mueller

  283
  Citations

• Protection against rotavirus-induced gastroenteritis in a murine model by passively acquired gastrointestinal but not circulating antibodies.

  P A Offit;H F Clark

  261
  Citations

• The development of multivalent bovine rotavirus (strain WC3) reassortant vaccine for infants.

  H F. Clark;P. A. Offit;R. W. Ellis;J. J. Eiden

  256
  Citations

• Reassortant rotaviruses containing structural proteins vp3 and vp7 from different parents induce antibodies protective against each parental serotype.

  P A Offit;H F Clark;G Blavat;H B Greenberg

  255
  Citations

• Protective Effect of WC3 Vaccine Against Rotavirus Diarrhea in Infants During a Predominantly Serotype 1 Rotavirus Season

  Unknown

  243
  Citations

• Safety, efficacy, and immunogenicity of a live, quadrivalent human-bovine reassortant rotavirus vaccine in healthy infants

  H.Fred Clark;David I Bernstein;Penelope H Dennehy;Paul Offit

  179
  Citations

• Effects of the potency and composition of the multivalent human-bovine (WC3) reassortant rotavirus vaccine on efficacy, safety and immunogenicity in healthy infants.

  Timo Vesikari;H Fred Clark;Paul A Offit;Michael J Dallas

  172
  Citations

• Molecular characterization of serotype G9 rotavirus strains from a global collection.

  M. Ramachandran;C.D. Kirkwood;L. Unicomb;N.A. Cunliffe;N.A. Cunliffe

  159
  Citations

• A murine model for oral infection with a primate rotavirus (simian SA11).

  P A Offit;H F Clark;M J Kornstein;S A Plotkin

  153
  Citations

• Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence.

  R L Broome;P T Vo;R L Ward;H F Clark

  147
  Citations

• Development of a Pentavalent Rotavirus Vaccine against Prevalent Serotypes of Rotavirus Gastroenteritis

  Penny M. Heaton;Michelle G. Goveia;Jacqueline M. Miller;Paul Offit

  139
  Citations

• Decline in Cases of Rotavirus Gastroenteritis Presenting to The Children's Hospital of Philadelphia after Introduction of a Pentavalent Rotavirus Vaccine

  H Fred Clark;Diane Lawley;Laura A. Mallette;Mark J. DiNubile

  123
  Citations

• Immune response of infants and children to low-passage bovine rotavirus (strain WC3).

  H F Clark;T Furukawa;L M Bell;P A Offit

  123
  Citations

• Serotypes and Electropherotypes of Human Rotavirus in the USA: 1987-1989

  Vera Gouvea;Mei-Shang Ho;Roger Glass;Patricia Woods

  117
  Citations

• Immune Protection of Infants against Rotavirus Gastroenteritis by a Serotype 1 Reassortant of Bovine Rotavirus WC3

  H F. Clark;F. E. Borian;S. A. Plotkin

  113
  Citations

• Maternal Antibody-Mediated Protection Against Gastroenteritis Due to Rotavirus in Newborn Mice is Dependent on Both Serotype and Titer of Antibody

  Offit Pa;Clark Hf

  111
  Citations

• Rotavirus pathology and pathophysiology.

  Greenberg Hb;Clark Hf;Offit Pa

  109
  Citations

• Assessment of the Epidemic Potential of a New Strain of Rotavirus Associated with the Novel G9 Serotype Which Caused an Outbreak in the United States for the First Time in the 1995-1996 Season

  H. Fred Clark;Diane A. Lawley;Alyssa Schaffer;Janice M. Patacsil

  106
  Citations

• The new pentavalent rotavirus vaccine composed of bovine (strain WC3) -human rotavirus reassortants.

  H Fred Clark;Paul A Offit;Stanley A Plotkin;Penny M Heaton

  101
  Citations

• Novel Rotavirus VP7 Typing Assay Using a One-Step Reverse Transcriptase PCR Protocol and Product Sequencing and Utility of the Assay for Epidemiological Studies and Strain Characterization, Including Serotype Subgroup Analysis

  Daniel J. DiStefano;Nikolai Kraiouchkine;Laura Mallette;Marianne Maliga

  96
  Citations

• Safety, immunogenicity and efficacy in healthy infants of G1 and G2 human reassortant rotavirus vaccine in a new stabilizer/buffer liquid formulation.

  H Fred Clark;Carl J Burke;David B Volkin;Paul Offit

  85
  Citations