2007 - Fellow of the American Association for the Advancement of Science (AAAS)
1978 - Wolf Prize in Agriculture for his outstanding research on the genetic amelioration of maize for human welfare.
1968 - Member of the National Academy of Sciences
George F. Sprague mainly investigates Saccharomyces cerevisiae, Genetics, Cell biology, Ste5 and Yeast. His Saccharomyces cerevisiae study combines topics from a wide range of disciplines, such as Cellular differentiation and Peptide. His MAPK/ERK pathway and Signal transduction study, which is part of a larger body of work in Cell biology, is frequently linked to Pseudohyphal growth, bridging the gap between disciplines.
His Ste5 research incorporates themes from MAPK7, Mating type and Mating Factor. His Yeast study integrates concerns from other disciplines, such as Amino acid, Plasmid and Mutant. His studies deal with areas such as Cell fusion and Plasma membrane fusion as well as Gene.
George F. Sprague focuses on Saccharomyces cerevisiae, Genetics, Cell biology, Gene and Signal transduction. His Saccharomyces cerevisiae research includes themes of Cell cycle, Transcription factor and Mutant. George F. Sprague combines subjects such as Polarisome and Receptor, Endocytosis, Endocytic cycle, Receptor-mediated endocytosis with his study of Cell biology.
His work in Gene tackles topics such as Molecular biology which are related to areas like Reporter gene, GAL4/UAS system, Binding site and G protein. His Signal transduction research is multidisciplinary, relying on both Plasma protein binding and Kinase. His Yeast research is multidisciplinary, incorporating perspectives in Plasmid, Budding, Computational biology and Bacteria.
George F. Sprague spends much of his time researching Genetics, Saccharomyces cerevisiae, Signal transduction, Yeast and Protein kinase A. The Transcription factor, Genome, Leucine zipper and Target protein research George F. Sprague does as part of his general Genetics study is frequently linked to other disciplines of science, such as ATF3, therefore creating a link between diverse domains of science. His Saccharomyces cerevisiae research incorporates themes from MAPK/ERK pathway and Cell polarity.
His Signal transduction study integrates concerns from other disciplines, such as Plasma protein binding and Computational biology. His Yeast genome study in the realm of Yeast interacts with subjects such as O-linked glycosylation, Protein glycosylation and Autoinducer. His Protein kinase A study contributes to a more complete understanding of Cell biology.
Signal transduction, Saccharomyces cerevisiae, Protein kinase A, Computational biology and Yeast are his primary areas of study. Signal transduction is a primary field of his research addressed under Cell biology. His work on Saccharomyces cerevisiae is being expanded to include thematically relevant topics such as Cellular differentiation.
His Protein kinase A research is classified as research in Biochemistry. His Computational biology study incorporates themes from Budding yeast, Microbiology and Bacteria.
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Bacterial conjugative plasmids mobilize DNA transfer between bacteria and yeast
Jack A. Heinemann;George F. Sprague.
Nature (1989)
Identification and characterization of dinucleotide repeat (CA)n markers for genetic mapping in dog
Elaine A. Ostrander;George F. Sprague;Jasper Rine.
Genomics (1993)
Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase
David Julius;Lindley Blair;Anthony Brake;George Sprague.
Cell (1983)
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.
J A Printen;G F Sprague.
Genetics (1994)
Glucose depletion causes haploid invasive growth in yeast
Paul J. Cullen;George F. Sprague.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.
Brian J. Stevenson;Nelson Rhodes;Beverly Errede;George F. Sprague.
Genes & Development (1992)
Assay of yeast mating reaction.
George F. Sprague.
Methods in Enzymology (1991)
Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors
Nicholas G. Davis;Joseph L. Horecka;George F. Sprague.
Journal of Cell Biology (1993)
12 Pheromone Response and Signal Transduction during the Mating Process of Saccharomyces cerevisiae
George F. Sprague;Jeremy W. Thorner.
Cold Spring Harbor Monograph Archive (1992)
Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.
G McCaffrey;F J Clay;K Kelsay;G F Sprague.
Molecular and Cellular Biology (1987)
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