George F. Sprague

Research.com Recognitions

• 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1978 - Wolf Prize in Agriculture for his outstanding research on the genetic amelioration of maize for human welfare.
• 1968 - Member of the National Academy of Sciences

Overview

Best Publications

• Bacterial conjugative plasmids mobilize DNA transfer between bacteria and yeast

  Jack A. Heinemann;George F. Sprague

  663
  Citations

• Identification and characterization of dinucleotide repeat (CA)n markers for genetic mapping in dog

  Elaine A. Ostrander;George F. Sprague;Jasper Rine

  549
  Citations

• Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase

  David Julius;Lindley Blair;Anthony Brake;George Sprague

  496
  Citations

• Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.

  J A Printen;G F Sprague

  464
  Citations

• Glucose depletion causes haploid invasive growth in yeast

  Paul J. Cullen;George F. Sprague

  430
  Citations

• Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.

  Brian J. Stevenson;Nelson Rhodes;Beverly Errede;George F. Sprague

  388
  Citations

• Assay of yeast mating reaction.

  George F. Sprague

  374
  Citations

• The Regulation of Filamentous Growth in Yeast

  Paul J. Cullen;George F. Sprague

  339
  Citations

• Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors

  Nicholas G. Davis;Joseph L. Horecka;George F. Sprague

  330
  Citations

• Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus

  Robert Jensen;George F. Sprague;Ira Herskowitz

  322
  Citations

• Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.

  G McCaffrey;F J Clay;K Kelsay;G F Sprague

  306
  Citations

• 12 Pheromone Response and Signal Transduction during the Mating Process of Saccharomyces cerevisiae

  George F. Sprague;Jeremy W. Thorner

  302
  Citations

• A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast

  Paul J. Cullen;Walid Sabbagh;Ellie Graham;Molly M. Irick

  272
  Citations

• MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

  Alan Bender;George F. Sprague

  272
  Citations

• Control of yeast cell type by the mating type locus. I. Identification and control of expression of the a-specific gene BAR1.

  George F. Sprague;Ira Herskowitz

  237
  Citations

• Cell Interactions and Regulation of Cell Type in the Yeast Saccharomyces Cerevisiae

  G F Sprague;L C Blair;J Thorner

  226
  Citations

• Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms.

  A. M. Neiman;B. J. Stevenson;Hao-Peng Xu;G. F. Sprague

  212
  Citations

• Pheromone response elements are necessary and sufficient for basal and pheromone-induced transcription of the FUS1 gene of Saccharomyces cerevisiae.

  D C Hagen;G McCaffrey;G F Sprague

  201
  Citations

• Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.

  B. J. Stevenson;B. Ferguson;C. De Virgilio;Erfei Bi

  191
  Citations

• The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene.

  E E Jarvis;K L Clark;G F Sprague

  183
  Citations