Edward R. Block

Overview

Best Publications

• Hyperuricemia induces endothelial dysfunction.

  Uday M. Khosla;Sergey Zharikov;Jennifer L. Finch;Takahiko Nakagawa

  1600
  Citations

• A causal role for uric acid in fructose-induced metabolic syndrome

  Takahiko Nakagawa;Hanbo Hu;Sergey Zharikov;Katherine R Tuttle

  1503
  Citations

• A Caveolar Complex between the Cationic Amino Acid Transporter 1 and Endothelial Nitric-oxide Synthase May Explain the “Arginine Paradox”

  Kelly K. McDonald;Sergei Zharikov;Edward R. Block;Michael S. Kilberg

  656
  Citations

• Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells

  Yunchao Su;Weihong Han;Carlos Giraldo;Yong De Li

  454
  Citations

• Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

  Sergey Zharikov;Karina Krotova;Hanbo Hu;Chris Baylis

  299
  Citations

• Regulation of endothelial nitric oxide synthase by the actin cytoskeleton.

  Yunchao Su;Sophia Edwards-Bennett;Michael R. Bubb;Michael R. Bubb;Edward R. Block;Edward R. Block

  159
  Citations

• Nitric oxide-induced persistent inhibition and nitrosylation of active site cysteine residues of mitochondrial cytochrome-c oxidase in lung endothelial cells.

  Jianliang Zhang;Bilian Jin;Liuzhe Li;Edward R. Block

  135
  Citations

• Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity.

  J M Patel;J Zhang;E R Block

  123
  Citations

• Mechanism of hypoxic injury to pulmonary artery endothelial cell plasma membranes.

  E. R. Block;J. M. Patel;D. Edwards

  115
  Citations

• Characterization of L-glutamine transport by pulmonary artery endothelial cells.

  K. Herskowitz;B. P. Bode;E. R. Block;W. W. Souba

  114
  Citations

• NO upregulation of a cyclic nucleotide-gated channel contributes to calcium elevation in endothelial cells

  Jianliang Zhang;Shen-Ling Xia;Shen-Ling Xia;Edward R. Block;Edward R. Block;Jawaharlal M. Patel;Jawaharlal M. Patel

  113
  Citations

• Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation

  Jawaharlal M. Patel;Jeffrey R. Martens;Yong D. Li;Craig H. Gelband

  113
  Citations

• Hypoxia inhibits L-arginine uptake by pulmonary artery endothelial cells

  E. R. Block;H. Herrera;M. Couch

  112
  Citations

• Effect of plasma membrane fluidity on serotonin transport by endothelial cells

  E. R. Block;D. Edwards

  111
  Citations

• Results of a prospective study evaluating the effects of mantle irradiation on pulmonary function.

  Lynn M. Smith;Nancy P. Mendenhall;Michael J. Cicale;Edward R. Block

  111
  Citations

• Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells

  Yunchao Su;Edward R. Block;Edward R. Block

  109
  Citations

• Hypoxic upregulation of arginase II in human lung endothelial cells

  Karina Y Krotova;Jawaharlal M. Patel;Jawaharlal M. Patel;Edward R. Block;Edward R. Block;Sergey Zharikov

  106
  Citations

• Hydrogen peroxide alters the physical state and function of the plasma membrane of pulmonary artery endothelial cells.

  Edward R. Block

  100
  Citations

• Calpain-2 regulation of VEGF-mediated angiogenesis

  Yunchao Su;Zhaoqiang Cui;Zhaozhong Li;Edward R. Block;Edward R. Block

  99
  Citations

• Cytoskeletal regulation of nitric oxide synthase.

  Yunchao Su;Dmitry Kondrikov;Edward R. Block

  96
  Citations