World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
31069
World Ranking
2538
National Ranking
60

Overview

Jie Du is affiliated with Capital Medical University in China and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans over 258 publications in Medicine and 116 in Biochemistry, Genetics, and Molecular Biology, highlighting a broad expertise within life sciences. Major subfields of study include Molecular Biology, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, Immunology, and Surgery.

Their work encompasses several main topics, notably cardiovascular and related disorders. The scientist has extensively explored areas such as aortic aneurysm repair treatments, aortic disease and treatment approaches, cardiac valve diseases and treatments, cardiovascular function and risk factors, microRNA in disease regulation, cardiac fibrosis and remodeling, and connective tissue disorders research.

Jie Du has published frequently in a variety of scientific venues. Key publication venues include Frontiers in Cardiovascular Medicine, SSRN Electronic Journal, Research Square, Journal of Biological Chemistry, and arXiv. These platforms reflect a spectrum of cardiovascular and molecular biology research themes.

Among recent papers authored or co-authored by Jie Du are the following:

  • "TMAO: how gut microbiota contributes to heart failure," 2020, Translational Research
  • "Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis," 2020, Cell Reports
  • "Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration," 2020, Journal of Cachexia Sarcopenia and Muscle
  • "The deubiquitinase UCHL1 regulates cardiac hypertrophy by stabilizing epidermal growth factor receptor," 2020, Science Advances
  • "Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy," 2020, JACC Basic to Translational Science

Collaboration is a notable aspect of Jie Du's research activity. Frequent co-authors include Yulin Li, Yuan Wang, Shijuan Gao, Congcong Zhang, and Lixin Jia, indicating a network of colleagues primarily involved in cardiovascular and molecular biology research.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions

    Jie Du;Xiaonan Wang;Christiane Miereles;James L. Bailey

  • Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling.

    Xiaonan Wang;Zhaoyong Hu;Junping Hu;Jie Du

  • Regulation of Muscle Protein Degradation: Coordinated Control of Apoptotic and Ubiquitin-Proteasome Systems by Phosphatidylinositol 3 Kinase

    Seoung Woo Lee;Guoli Dai;Zhaoyong Hu;Xiaonan Wang

  • Muscle-specific expression of IGF-1 blocks angiotensin II–induced skeletal muscle wasting

    Yao-Hua Song;Yangxin Li;Jie Du;William E. Mitch

  • Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

    Liping Zhang;Vik Rajan;Eugene Lin;Zhaoyong Hu

  • Macrophage-Derived mir-155-Containing Exosomes Suppress Fibroblast Proliferation and Promote Fibroblast Inflammation during Cardiac Injury

    Chunxiao Wang;Chunxiao Wang;Congcong Zhang;Congcong Zhang;Luxin Liu;Luxin Liu;Xi A;Xi A

  • Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF β/Smad activation and cardiac fibrosis induced by angiotensin II.

    Feifei Ma;Yulin Li;Lixin Jia;Yalei Han

  • IL-6 and Serum Amyloid A Synergy Mediates Angiotensin II–Induced Muscle Wasting

    Liping Zhang;Jie Du;Zhaoyong Hu;Guofeng Han

  • Interleukin-6/Signal Transducer and Activator of Transcription 3 (STAT3) Pathway Is Essential for Macrophage Infiltration and Myoblast Proliferation during Muscle Regeneration

    Congcong Zhang;Yulin Li;Yina Wu;Luya Wang

  • IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult.

    Han Xiao;Hao Li;Jing-Jing Wang;Jian-Shu Zhang

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development

    Juan Lin;Hanjie Li;Min Yang;Junming Ren

  • Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice

    Zhaoyong Hu;Huiling Wang;In Hee Lee;Jie Du

  • Satellite Cell Dysfunction and Impaired IGF-1 Signaling Cause CKD-Induced Muscle Atrophy

    Liping Zhang;Xiaonan H. Wang;Huiling Wang;Jie Du

  • CXCL1-CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration.

    Lei Wang;Yun-Long Zhang;Qiu-Yue Lin;Yu Liu

  • Monocytic Fibroblast Precursors Mediate Fibrosis in Angiotensin-II-induced Cardiac Hypertrophy

    Sandra B. Haudek;Jizhong Cheng;Jie Du;Yanlin Wang

  • S100a8/a9 Signaling Causes Mitochondrial Dysfunction and Cardiomyocyte Death in Response to Ischemic/Reperfusion Injury.

    Yulin Li;Boya Chen;Xinying Yang;Congcong Zhang

  • Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

    Fuli Zhu;Yulin Li;Junmeng Zhang;Chunmei Piao

  • TMAO: how gut microbiota contributes to heart failure.

    Yixin Zhang;Yuan Wang;Bingbing Ke;Jie Du

Frequent Co-Authors

William E. Mitch
William E. Mitch Baylor College of Medicine
Chaoshu Tang
Chaoshu Tang Peking University
Zhi-Cheng Xiao
Zhi-Cheng Xiao Monash University
Fu-Jian Xu
Fu-Jian Xu Beijing University of Chemical Technology
Janet D. Klein
Janet D. Klein Emory University
Jiahuai Han
Jiahuai Han Xiamen University
Erhe Gao
Erhe Gao Temple University
Luan D. Truong
Luan D. Truong Cornell University
Xiuqing Zhang
Xiuqing Zhang China Agricultural University
huanming yang
huanming yang Beijing Genomics Institute

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