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Biology and Biochemistry

D-Index
76
Citations
15969
World Ranking
5157
National Ranking
393

Overview

David C. Warhurst was affiliated with the London School of Hygiene & Tropical Medicine in the United Kingdom. Their research spanned multiple fields, including Medicine and Chemistry, with specific focus areas within Epidemiology, Public Health, Environmental and Occupational Health, and Organic Chemistry.

Their scientific contributions centered on the study of Trypanosoma species and the implications of this research for infectious diseases. They also worked on research related to Leishmaniasis and engaged in projects involving synthesis and biological evaluation.

Among their publications, a significant paper was titled "Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity", published in 2020 in the International Journal for Parasitology Drugs and Drug Resistance.

Frequent collaborators in their work included:

  • Caio Haddad Franco
  • Tapan Bhattacharyya
  • Ho Y.A. Au
  • Hai Le
  • Miriam A. Giardini

Their work was primarily published in the venue:

  • International Journal for Parasitology Drugs and Drug Resistance

Key research topics covered throughout their career included:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Synthesis and Biological Evaluation

Best Publications

  • ACP Broadsheet no 148. July 1996. Laboratory diagnosis of malaria.

    D C Warhurst;J E Williams

  • Lysosomes, pH and the Anti-malarial Action of Chloroquine

    C. A. Homewood;D. C. Warhurst;W. Peters;V. C. Baggaley

  • Accuracy of routine laboratory diagnosis of malaria in the United Kingdom.

    L M Milne;M S Kyi;P L Chiodini;D C Warhurst

  • Modified Fixed-Ratio Isobologram Method for Studying In Vitro Interactions between Atovaquone and Proguanil or Dihydroartemisinin against Drug-Resistant Strains of Plasmodium falciparum

    Quinton L. Fivelman;Ipemida S. Adagu;David C. Warhurst

  • The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

    Duraisingh;P Jones;I Sambou;L von Seidlein

  • Plasmodium falciparum:Detection of Polymorphisms in theDihydrofolate ReductaseandDihydropteroate SynthetaseGenes by PCR and Restriction Digestion

    Manoj T. Duraisingh;Jill Curtis;David C. Warhurst

  • Efficacy of artesunate plus pyrimethamine-sulphadoxine for uncomplicated malaria in Gambian children: a double-blind, randomised, controlled trial

    L von Seidlein;P Milligan;M Pinder;K Bojang

  • Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum.

    Manoj T. Duraisingh;Cally Roper;David Walliker;David C. Warhurst

  • In vitro and In vivo evaluation of betulinic acid as an antimalarial

    J. C. P. Steele;D. C. Warhurst;G. C. Kirby;M. S. J. Simmonds

  • In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.

    I Sullayman Adagu;Deborah Nolder;David C Warhurst;Jean-François Rossignol

  • Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates.

    Amir Hossein Maghsood;James Sissons;Mostafa Rezaian;Debbie Nolder

  • Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids.

    C W Wright;M J O'Neill;J D Phillipson;D C Warhurst

  • Malarone Treatment Failure and in Vitro Confirmation of Resistance of Plasmodium Falciparum Isolate From Lagos, Nigeria

    Quinton L Fivelman;Geoffrey A Butcher;Ipemida S Adagu;David C Warhurst

  • Separation of malaria-infected erythrocytes from whole blood: use of a selective high-gradient magnetic separation technique.

    F. Paul;S. Roath;D. Melville;D.C. Warhurst

  • Plants as Sources of Antimalarial Drugs Part. 1. In vitro Test Method for the Evaluation of Crude Extracts from Plants

    M. J. O'Neill;D. H. Bray;P. Boardman;J. D. Phillipson

  • Acanthamoeba keratitis successfully treated medically.

    Peter Wright;David Warhurst;Barrie R Jones

  • Plants as sources of antimalarial drugs. Part 7. Activity of some species of meliaceae plants and their constituent limonoids

    D. H. Bray;D. C. Warhurst;J. D. Connolly;M. J. O'Neill

  • Plants as Sources of Antimalarial Drugs. Part 31 Eurycoma longifolia

    Kit L. Chan;Melanie J. O'Neill;J. David Phillipson;David C. Warhurst

  • Evidence for selection for the tyrosine-86 allele of the pfmdr 1 gene of Plasmodium falciparum by chloroquine and amodiaquine.

    M. T. Duraisingh;C. J. Drakeley;O. Muller;R. Bailey

  • A Molecular Marker for Chloroquine-Resistant Falciparum Malaria

    David C. Warhurst

Frequent Co-Authors

Manoj T. Duraisingh
Manoj T. Duraisingh Harvard University
Colin J. Sutherland
Colin J. Sutherland London School of Hygiene & Tropical Medicine
Michael A. Miles
Michael A. Miles London School of Hygiene & Tropical Medicine
Valerie J. Smith
Valerie J. Smith Trinity College Dublin
Jim Todd
Jim Todd London School of Hygiene & Tropical Medicine
Mark Urassa
Mark Urassa Medical Research Council
Monique S. J. Simmonds
Monique S. J. Simmonds Royal Botanic Gardens
Brian Greenwood
Brian Greenwood London School of Hygiene & Tropical Medicine
Naveed Ahmed Khan
Naveed Ahmed Khan University of Sharjah
Margaret Pinder
Margaret Pinder Durham University

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