His scientific interests lie mostly in Plasmodium falciparum, Malaria, Microbiology, Pharmacology and Chloroquine. His Plasmodium falciparum research is multidisciplinary, relying on both Genetics, In vitro, Drug resistance and Virology. David C. Warhurst interconnects Surgery and Emergency medicine in the investigation of issues within Malaria.
The concepts of his Microbiology study are interwoven with issues in Keratitis and Bacteria. His Pharmacology study which covers Dihydroartemisinin that intersects with Halofantrine, Proguanil, Drug and Quinine. The study incorporates disciplines such as Multiple drug resistance, Artemisinin, Pigment and Genotype in addition to Chloroquine.
David C. Warhurst focuses on Plasmodium falciparum, Malaria, Chloroquine, Pharmacology and Microbiology. His studies deal with areas such as Genetics, In vitro, Drug resistance, Biological activity and Virology as well as Plasmodium falciparum. His study looks at the relationship between Virology and topics such as Dihydrofolate reductase, which overlap with Dihydropteroate synthase, DHPS, Sulfadoxine, Dihydropteroate and Sulfadoxine/pyrimethamine.
His work carried out in the field of Malaria brings together such families of science as Surgery, Haplotype and Environmental health. His work in the fields of Chloroquine, such as Mefloquine, overlaps with other areas such as Rodent. The various areas that David C. Warhurst examines in his Pharmacology study include Amodiaquine, Quinine and Artemisinin, Piperaquine, Dihydroartemisinin.
The scientist’s investigation covers issues in Plasmodium falciparum, Malaria, Chloroquine, Genetics and Drug resistance. David C. Warhurst conducted interdisciplinary study in his works that combined Plasmodium falciparum and Comparative genomics. His work deals with themes such as Family medicine, Haplotype and Environmental health, which intersect with Malaria.
David C. Warhurst combines subjects such as Biochemistry, Piperaquine and Pharmacology with his study of Chloroquine. His study looks at the relationship between Pharmacology and fields such as Atovaquone, as well as how they intersect with chemical problems. His work in Genetics addresses issues such as DHPS, which are connected to fields such as Lineage, Pyrimethamine, Sulfadoxine/pyrimethamine and Nested polymerase chain reaction.
David C. Warhurst mostly deals with Plasmodium falciparum, Immunology, Chloroquine, Haplotype and Malaria. His studies in Plasmodium falciparum integrate themes in fields like Drug resistance and Pharmacology. As a part of the same scientific study, David C. Warhurst usually deals with the Drug resistance, concentrating on Atovaquone and frequently concerns with In vivo and In vitro.
His Immunology research is multidisciplinary, incorporating perspectives in Epidemiology, Central nervous system disease and Granulomatous amoebic encephalitis. His Chloroquine research is multidisciplinary, incorporating elements of Efflux, Biochemistry and Genotype. Malaria is closely attributed to Virology in his study.
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Lysosomes, pH and the Anti-malarial Action of Chloroquine
C. A. Homewood;D. C. Warhurst;W. Peters;V. C. Baggaley.
ACP Broadsheet no 148. July 1996. Laboratory diagnosis of malaria.
D C Warhurst;J E Williams.
Journal of Clinical Pathology (1996)
Accuracy of routine laboratory diagnosis of malaria in the United Kingdom.
L M Milne;M S Kyi;P L Chiodini;D C Warhurst.
Journal of Clinical Pathology (1994)
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin
Duraisingh;P Jones;I Sambou;L von Seidlein.
Molecular and Biochemical Parasitology (2000)
Modified Fixed-Ratio Isobologram Method for Studying In Vitro Interactions between Atovaquone and Proguanil or Dihydroartemisinin against Drug-Resistant Strains of Plasmodium falciparum
Quinton L. Fivelman;Ipemida S. Adagu;David C. Warhurst.
Antimicrobial Agents and Chemotherapy (2004)
Plasmodium falciparum:Detection of Polymorphisms in theDihydrofolate ReductaseandDihydropteroate SynthetaseGenes by PCR and Restriction Digestion
Manoj T. Duraisingh;Jill Curtis;David C. Warhurst.
Experimental Parasitology (1998)
Efficacy of artesunate plus pyrimethamine-sulphadoxine for uncomplicated malaria in Gambian children: a double-blind, randomised, controlled trial
L von Seidlein;P Milligan;M Pinder;K Bojang.
The Lancet (2000)
Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum.
Manoj T. Duraisingh;Cally Roper;David Walliker;David C. Warhurst.
Molecular Microbiology (2000)
Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids.
C W Wright;M J O'Neill;J D Phillipson;D C Warhurst.
Antimicrobial Agents and Chemotherapy (1988)
In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.
I Sullayman Adagu;Deborah Nolder;David C Warhurst;Jean-François Rossignol.
Journal of Antimicrobial Chemotherapy (2002)
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