D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 64 Citations 11,726 178 World Ranking 6389 National Ranking 485

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His scientific interests lie mostly in Plasmodium falciparum, Malaria, Microbiology, Pharmacology and Chloroquine. His Plasmodium falciparum research is multidisciplinary, relying on both Genetics, In vitro, Drug resistance and Virology. David C. Warhurst interconnects Surgery and Emergency medicine in the investigation of issues within Malaria.

The concepts of his Microbiology study are interwoven with issues in Keratitis and Bacteria. His Pharmacology study which covers Dihydroartemisinin that intersects with Halofantrine, Proguanil, Drug and Quinine. The study incorporates disciplines such as Multiple drug resistance, Artemisinin, Pigment and Genotype in addition to Chloroquine.

His most cited work include:

  • Lysosomes, pH and the Anti-malarial Action of Chloroquine (347 citations)
  • ACP Broadsheet no 148. July 1996. Laboratory diagnosis of malaria. (287 citations)
  • The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin (246 citations)

What are the main themes of his work throughout his whole career to date?

David C. Warhurst focuses on Plasmodium falciparum, Malaria, Chloroquine, Pharmacology and Microbiology. His studies deal with areas such as Genetics, In vitro, Drug resistance, Biological activity and Virology as well as Plasmodium falciparum. His study looks at the relationship between Virology and topics such as Dihydrofolate reductase, which overlap with Dihydropteroate synthase, DHPS, Sulfadoxine, Dihydropteroate and Sulfadoxine/pyrimethamine.

His work carried out in the field of Malaria brings together such families of science as Surgery, Haplotype and Environmental health. His work in the fields of Chloroquine, such as Mefloquine, overlaps with other areas such as Rodent. The various areas that David C. Warhurst examines in his Pharmacology study include Amodiaquine, Quinine and Artemisinin, Piperaquine, Dihydroartemisinin.

He most often published in these fields:

  • Plasmodium falciparum (35.90%)
  • Malaria (26.67%)
  • Chloroquine (19.49%)

What were the highlights of his more recent work (between 2003-2020)?

  • Plasmodium falciparum (35.90%)
  • Malaria (26.67%)
  • Chloroquine (19.49%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Plasmodium falciparum, Malaria, Chloroquine, Genetics and Drug resistance. David C. Warhurst conducted interdisciplinary study in his works that combined Plasmodium falciparum and Comparative genomics. His work deals with themes such as Family medicine, Haplotype and Environmental health, which intersect with Malaria.

David C. Warhurst combines subjects such as Biochemistry, Piperaquine and Pharmacology with his study of Chloroquine. His study looks at the relationship between Pharmacology and fields such as Atovaquone, as well as how they intersect with chemical problems. His work in Genetics addresses issues such as DHPS, which are connected to fields such as Lineage, Pyrimethamine, Sulfadoxine/pyrimethamine and Nested polymerase chain reaction.

Between 2003 and 2020, his most popular works were:

  • Modified Fixed-Ratio Isobologram Method for Studying In Vitro Interactions between Atovaquone and Proguanil or Dihydroartemisinin against Drug-Resistant Strains of Plasmodium falciparum (206 citations)
  • Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates. (130 citations)
  • Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. (87 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

David C. Warhurst mostly deals with Plasmodium falciparum, Immunology, Chloroquine, Haplotype and Malaria. His studies in Plasmodium falciparum integrate themes in fields like Drug resistance and Pharmacology. As a part of the same scientific study, David C. Warhurst usually deals with the Drug resistance, concentrating on Atovaquone and frequently concerns with In vivo and In vitro.

His Immunology research is multidisciplinary, incorporating perspectives in Epidemiology, Central nervous system disease and Granulomatous amoebic encephalitis. His Chloroquine research is multidisciplinary, incorporating elements of Efflux, Biochemistry and Genotype. Malaria is closely attributed to Virology in his study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Lysosomes, pH and the Anti-malarial Action of Chloroquine

C. A. Homewood;D. C. Warhurst;W. Peters;V. C. Baggaley.
Nature (1972)

479 Citations

ACP Broadsheet no 148. July 1996. Laboratory diagnosis of malaria.

D C Warhurst;J E Williams.
Journal of Clinical Pathology (1996)

476 Citations

Accuracy of routine laboratory diagnosis of malaria in the United Kingdom.

L M Milne;M S Kyi;P L Chiodini;D C Warhurst.
Journal of Clinical Pathology (1994)

402 Citations

The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

Duraisingh;P Jones;I Sambou;L von Seidlein.
Molecular and Biochemical Parasitology (2000)

332 Citations

Modified Fixed-Ratio Isobologram Method for Studying In Vitro Interactions between Atovaquone and Proguanil or Dihydroartemisinin against Drug-Resistant Strains of Plasmodium falciparum

Quinton L. Fivelman;Ipemida S. Adagu;David C. Warhurst.
Antimicrobial Agents and Chemotherapy (2004)

312 Citations

Plasmodium falciparum:Detection of Polymorphisms in theDihydrofolate ReductaseandDihydropteroate SynthetaseGenes by PCR and Restriction Digestion

Manoj T. Duraisingh;Jill Curtis;David C. Warhurst.
Experimental Parasitology (1998)

305 Citations

Efficacy of artesunate plus pyrimethamine-sulphadoxine for uncomplicated malaria in Gambian children: a double-blind, randomised, controlled trial

L von Seidlein;P Milligan;M Pinder;K Bojang.
The Lancet (2000)

250 Citations

Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum.

Manoj T. Duraisingh;Cally Roper;David Walliker;David C. Warhurst.
Molecular Microbiology (2000)

241 Citations

Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids.

C W Wright;M J O'Neill;J D Phillipson;D C Warhurst.
Antimicrobial Agents and Chemotherapy (1988)

212 Citations

In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis.

I Sullayman Adagu;Deborah Nolder;David C Warhurst;Jean-François Rossignol.
Journal of Antimicrobial Chemotherapy (2002)

212 Citations

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