Cynthia J. Guidos

Best Publications

• Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

  Ansuman T. Satpathy;Carlos G. Briseño;Jacob S. Lee;Dennis Ng

  498
  Citations

• Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes.

  Klaus-Dieter Fischer;Klaus-Dieter Fischer;Antanina Zmuidzinas;Sandra Gardner;Sandra Gardner;Mariano Barbacid

  367
  Citations

• V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

  Unknown

  341
  Citations

• Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia.

  Ming Chen;Darrell J. Tomkins;Wojtek Auerbach;Colin McKerlie

  317
  Citations

• T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.

  C J Guidos;J S Danska;C G Fathman;I L Weissman

  251
  Citations

• Requirement for Notch1 signals at sequential early stages of intrathymic T cell development.

  Unknown

  250
  Citations

• Subversion of the T/B Lineage Decision in the Thymus by Lunatic Fringe-Mediated Inhibition of Notch-1

  Unknown

  241
  Citations

• Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.

  Unknown

  239
  Citations

• Functions of Notch Signaling in the Immune System: Consensus and Controversies

  Unknown

  222
  Citations

• Intrathymic maturation of murine T lymphocytes from CD8+ precursors.

  Cynthia J. Guidos;Irving L. Weissman;Becky Adkins

  184
  Citations

• Notch signal strength controls cell fate in the haemogenic endothelium

  Leonor Gama-Norton;Eva Ferrando;Cristina Ruiz-Herguido;Zhenyi Liu

  182
  Citations

• Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.

  Ramy Gadalla;Babak Noamani;Bethany L. MacLeod;Russell J. Dickson

  173
  Citations

• Zebrafish screen identifies novel compound with selective toxicity against leukemia

  Suzanne Ridges;Will L. Heaton;Deepa Joshi;Henry Choi

  168
  Citations

• Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor.

  C L Verweij;C Guidos;G R Crabtree

  160
  Citations

• Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.

  Unknown

  151
  Citations

• Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.

  C Y Okada;B Holzmann;C Guidos;E Palmer

  143
  Citations

• CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

  Laura M. Snell;Bethany L. MacLeod;Jaclyn C. Law;Ivan Osokine

  141
  Citations

• Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents

  Jayne S. Danska;Françoise Pflumio;Christine J. Williams;Ozgur Huner

  139
  Citations

• IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.

  Amine Boudil;Irina R Matei;Han-Yu Shih;Goce Bogdanoski

  131
  Citations

• Regulation of T lymphopoiesis by Notch1 and Lunatic fringe–mediated competition for intrathymic niches

  Unknown

  130
  Citations