Brian S. Meldrum

Overview

Best Publications

• Excitatory amino acid neurotoxicity and neurodegenerative disease

  Brian Meldrum;John Garthwaite

  2843
  Citations

• Glutamate as a Neurotransmitter in the Brain: Review of Physiology and Pathology

  Brian S. Meldrum

  2237
  Citations

• Molecular Targets for Antiepileptic Drug Development

  Brian S. Meldrum;Michael A. Rogawski

  604
  Citations

• Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters.

  Unknown

  543
  Citations

• Prolonged Epileptic Seizures in Primates

  Unknown

  535
  Citations

• Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat.

  R. P. Simon;T. Griffiths;M. C. Evans;J. H. Swan

  522
  Citations

• Epilepsy and γ-Aminobutyric Acid-Mediated Inhibition

  Unknown

  491
  Citations

• Systemic Factors and Epileptic Brain Damage

  Unknown

  446
  Citations

• Na+ channels as targets for neuroprotective drugs.

  Charles P. Taylor;Brian S. Meldrum

  386
  Citations

• Mechanism of anticonvulsant action of valproate

  Unknown

  344
  Citations

• Physiology of status epilepticus in primates.

  Unknown

  342
  Citations

• CEREBRAL METABOLIC CHANGES DURING PROLONGED EPILEPTIC SEIZURES IN RATS

  Unknown

  334
  Citations

• The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

  Eliane Le Pillet;Babak Arvin;Claudia Moncada;Brian S. Meldrum

  314
  Citations

• Cerebral blood flow and metabolic rate early and late in prolonged epileptic seizures induced in rats by bicuculline.

  Unknown

  304
  Citations

• An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus.

  M.C. Evans;J.H. Swan;B.S. Meldrum

  280
  Citations

• The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

  Astrid G. Chapman;Stuart E. Smith;Brian S. Meldrum

  274
  Citations

• Kynurenate inhibition of cell excitation decreases stroke size and deficits

  Isabelle M. Germano;Lawrence H. Pitts;Brian S. Meldrum;Henry M. Bartkowski

  269
  Citations

• Update on the Mechanism of Action of Antiepileptic Drugs

  Unknown

  265
  Citations

• Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, papio papio

  B.S. Meldrum;M.J. Croucher;G. Badman;J.F. Collins

  264
  Citations

• Amino Acid Neurotransmitters and New Approaches to Anticonvulsant Drug Action

  Brian Meldrum

  254
  Citations

• The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy.

  Stuart E. Smith;Nick Durmuller;Brian S. Meldrum

  245
  Citations

• Intracellular calcium accumulation in rat hippocampus during seizures induced by bicuculline or L-allylglycine.

  T. Griffiths;M.C. Evans;B.S. Meldrum

  240
  Citations

• Protection by NMDA antagonists against selective cell loss following transient ischaemia.

  Jeanette H. Swan;Brian S. Meldrum

  233
  Citations

• Glutamate metabotropic receptors as targets for drug therapy in epilepsy

  Randall Xavier Moldrich;Astrid G Chapman;Giovambattista De Sarro;Brian S Meldrum

  228
  Citations

• Induction of audiogenic seizure susceptibility by focal infusion of excitant amino acid or bicuculline into the inferior colliculus of normal rats.

  Maria H. Millan;Brian S. Meldrum;Carl L. Faingold

  217
  Citations

• Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).

  Astrid G Chapman;Karl Nanan;Martin Williams;Brian S Meldrum

  210
  Citations

• Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.

  L. Turski;E.A. Cavalheiro;W.A. Turski;B.S. Meldrum

  206
  Citations

• Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze.

  C.A. Netto;H. Hodges;J.D. Sinden;E. Le Peillet

  206
  Citations

• Cerebroprotective Effect of Lamotrigine After Focal Ischemia in Rats

  Stuart E. Smith;Brian S. Meldrum

  205
  Citations

• 9. Excitotoxicity and epileptic brain damage

  Brian Meldrum

  196
  Citations