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Chemistry

D-Index
111
Citations
48684
World Ranking
768
National Ranking
309

Overview

Brian M. Hoffman is affiliated with Northwestern University in the United States. Their research primarily spans energy, chemistry, and biochemistry, genetics, and molecular biology, with a strong focus on renewable energy, sustainability, and the environment.

Their work intersects multiple subfields, including inorganic chemistry, molecular biology, materials chemistry, and catalysis. Specific research topics emphasize metalloenzymes and iron-sulfur proteins, metal-catalyzed oxygenation mechanisms, ammonia synthesis and nitrogen reduction, electrocatalysts for energy conversion, CO2 reduction techniques and catalysts, photosynthetic processes and mechanisms, and electron spin resonance studies.

Brian M. Hoffman has contributed to several leading scientific journals. Frequent publication venues include the Journal of the American Chemical Society, Proceedings of the National Academy of Sciences, Biochemistry, Angewandte Chemie International Edition, and mBio.

Their collaborations include multiple frequent co-authors, such as Hao Yang, William E. Broderick, Joan Broderick, Lance C. Seefeldt, and Dennis R. Dean.

Selected recent publications are:

  • Reduction of Substrates by Nitrogenases, 2020, Chemical Reviews
  • Cobalt-Carbon Bonding in a Salen-Supported Cobalt(IV) Alkyl Complex Postulated in Oxidative MHAT Catalysis, 2022, Journal of the American Chemical Society
  • Structural and spectroscopic characterization of an Fe(VI) bis(imido) complex, 2020, Science
  • Effects of Desiccation and Freezing on Microbial Ionizing Radiation Survivability: Considerations for Mars Sample Return, 2022, Astrobiology
  • Coordination of the Copper Centers in Particulate Methane Monooxygenase: Comparison between Methanotrophs and Characterization of the CuCSite by EPR and ENDOR Spectroscopies, 2021, Journal of the American Chemical Society

Best Publications

  • Beyond fossil fuel-driven nitrogen transformations.

    Jingguang G. Chen;Jingguang G. Chen;Richard M. Crooks;Lance C. Seefeldt;Kara L. Bren

  • Mechanism of Nitrogen Fixation by Nitrogenase: The Next Stage

    Brian M. Hoffman;Dmitriy Lukoyanov;Zhi Yong Yang;Dennis R. Dean

  • Mechanism of Mo-Dependent Nitrogenase

    Lance C. Seefeldt;Brian M. Hoffman;Dennis R. Dean

  • Identification by ENDOR of Trp191 as the free-radical site in cytochrome c peroxidase compound ES

    Mohanram Sivaraja;David B. Goodin;Michael Smith;Brian M. Hoffman

  • Cytochrome c activation of CPP32‐like proteolysis plays a critical role in a Xenopus cell‐free apoptosis system

    Ruth M. Kluck;Seamus J. Martin;Brian M. Hoffman;Jian S. Zhou

  • CHEMICAL, SPECTRAL, STRUCTURAL, AND CHARGE TRANSPORT PROPERTIES OF THE “MOLECULAR METALS” PRODUCED BY IODINATION OF NICKEL PHTHALOCYANINE

    C. J. Schramm;R. P. Scaringe;D. R. Stojakovic;B. M. Hoffman

  • Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes.

    Roman Davydov;Thomas M. Makris;Victoria Kofman;David E. Werst

  • Climbing nitrogenase: Toward a mechanism of enzymatic nitrogen fixation

    Brian M. Hoffman;Dennis R. Dean;Lance C. Seefeldt

  • Nitrogenase: a draft mechanism.

    Brian M. Hoffman;Dmitriy Lukoyanov;Dennis R. Dean;Lance C. Seefeldt

  • Reduction of Substrates by Nitrogenases

    Lance C. Seefeldt;Zhi Yong Yang;Dmitriy A. Lukoyanov;Derek F. Harris

  • Gated electron transfer: when are observed rates controlled by conformational interconversion?

    Brian M. Hoffman;Mark A. Ratner

  • Electron paramagnetic resonance studies of some cobalt(II) Schiff base compounds and their monomeric oxygen adducts

    Brian Mark Hoffman;Damon L. Diemente;Fred Basolo

  • Synthetic Oxygen Carriers of Biological Interest

    Fred Basolo;Brian M. Hoffman;James A. Ibers

  • A new class of highly conductive molecular solids: the partially oxidized phthalocyanines

    J. L. Petersen;C. S. Schramm;D. R. Stojakovic;Brian M Hoffman

  • Reconsideration of X, the Diiron Intermediate Formed during Cofactor Assembly in E. coli Ribonucleotide Reductase

    Bradley E. Sturgeon;Doug Burdi;Shuxian Chen;Boi Hanh Huynh

  • Particulate methane monooxygenase contains only mononuclear copper centers

    Matthew O. Ross;Fraser MacMillan;Jingzhou Wang;Alex Nisthal

  • Porphyrinic molecular metals

    Brian M. Hoffman;James A. Ibers

  • Electron−nuclear double resonance spectroscopy of 15N-enriched phthalate dioxygenase from Pseudomonas cepacia proves that two histidines are coordinated to the [2Fe-2S] Rieske-type clusters

    Ryszard J. Gurbiel;Christopher J. Batie;Mohanram Sivaraja;Anne E. True

  • The Yeast Iron Regulatory Proteins Grx3/4 and Fra2 Form Heterodimeric Complexes Containing a [2Fe-2S] Cluster with Cysteinyl and Histidyl Ligation

    Haoran Li;Daphne T. Mapolelo;Nin N. Dingra;Sunil G. Naik

  • An anchoring role for FeS clusters: Chelation of the amino acid moiety of s-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme

    Charles J. Walsby;Danilo Ortillo;William E. Broderick;Joan B. Broderick

  • Theory and Practice of Electron Transfer within Proteinminus signProtein Complexes: Application to the Multidomain Binding of Cytochrome c by Cytochrome c Peroxidase.

    Judith M. Nocek;Jian S. Zhou;Sarah De Forest;Satyam Priyadarshy

Frequent Co-Authors

Anthony G. M. Barrett
Anthony G. M. Barrett Imperial College London
Lance C. Seefeldt
Lance C. Seefeldt Utah State University
Dennis R. Dean
Dennis R. Dean Virginia Tech
Joshua Telser
Joshua Telser Roosevelt University
Amy C. Rosenzweig
Amy C. Rosenzweig Northwestern University
Joan B. Broderick
Joan B. Broderick Montana State University
Charlotte L. Stern
Charlotte L. Stern Northwestern University
Andrew J. P. White
Andrew J. P. White Imperial College London
Victoria J. DeRose
Victoria J. DeRose University of Oregon

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