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Biology and Biochemistry

D-Index
59
Citations
44013
World Ranking
12236
National Ranking
117

Overview

Zvulun Elazar is affiliated with the Weizmann Institute of Science in Israel and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans various subfields including Epidemiology, Molecular Biology, Cell Biology, Physiology, and Cellular and Molecular Neuroscience.

Their research focuses on several key topics as follows:

  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • Cellular transport and secretion
  • Endoplasmic Reticulum Stress and Disease
  • Calcium signaling and nucleotide metabolism
  • RNA Interference and Gene Delivery
  • Adenosine and Purinergic Signaling

Zvulun Elazar has authored multiple recent papers including:

  • "Regulation of PRKN-independent mitophagy," 2021, Autophagy
  • "Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2," 2020, Autophagy
  • "Phospholipid imbalance impairs autophagosome completion," 2022, The EMBO Journal
  • "A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation," 2020, Autophagy
  • "Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins," 2022, Proceedings of the National Academy of Sciences

Their frequent co-authors include:

  • Milana Fraiberg
  • Oren Shatz
  • Christian Behrends
  • Nemanja Subic
  • Karsten Nalbach

Zvulun Elazar publishes regularly in several journals, with notable frequency in:

  • Autophagy
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The EMBO Journal
  • Nature Communications

In addition to journal articles, Zvulun Elazar has contributed to book publications, including a 2023 title titled Autophagy and Autophagy Genes in Pathophysiology of Human Disease and Ageing published by Frontiers Media.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

    Ruth Scherz-Shouval;Elena Shvets;Ephraim Fass;Hagai Shorer

  • Mechanism and medical implications of mammalian autophagy

    Ivan Dikic;Zvulun Elazar

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Regulation of autophagy by ROS: physiology and pathology

    Ruth Scherz-Shouval;Zvulun Elazar

  • A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

    Vladimir Kirkin;Trond Lamark;Yu Shin Sou;Geir Bjørkøy

  • ROS, mitochondria and the regulation of autophagy

    Ruth Scherz-Shouval;Zvulun Elazar

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

    Hilla Weidberg;Elena Shvets;Tomer Shpilka;Frida Shimron

  • Does bafilomycin A1 block the fusion of autophagosomes with lysosomes

    Daniel J. Klionsky;Zvulun Elazar;Per Ottar Seglen;David C. Rubinsztein

  • Atg8: an autophagy-related ubiquitin-like protein family

    Tomer Shpilka;Hilla Weidberg;Shmuel Pietrokovski;Zvulun Elazar

  • Biogenesis and Cargo Selectivity of Autophagosomes

    Hilla Weidberg;Elena Shvets;Zvulun Elazar

  • Mechanisms of autophagosome biogenesis.

    David C. Rubinsztein;Tomer Shpilka;Zvulun Elazar

  • A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

    Daniel J Klionsky;Eric H. Baehrecke;John H. Brumell;Charleen T. Chu

  • Stepwise assembly of functionally active transport vesicles

    Joachim Ostermann;Lelio Orci;Katsuko Tani;Mylene Amherdt

  • LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis.

    Hilla Weidberg;Tomer Shpilka;Elena Shvets;Adi Abada

  • Altered Autophagy in Human Adipose Tissues in Obesity

    Julia Kovsan;Matthias Blüher;Tanya Tarnovscki;Nora Klöting

  • Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.

    Ephraim Fass;Elena Shvets;Ilan Degani;Koret Hirschberg

Frequent Co-Authors

David C. Rubinsztein
David C. Rubinsztein University of Cambridge
Anne Simonsen
Anne Simonsen University of Oslo
Sharon A. Tooze
Sharon A. Tooze The Francis Crick Institute
Noboru Mizushima
Noboru Mizushima University of Tokyo
Daniel J. Klionsky
Daniel J. Klionsky University of Michigan–Ann Arbor
Eeva-Liisa Eskelinen
Eeva-Liisa Eskelinen University of Turku
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Guido Kroemer
Guido Kroemer Université Paris Cité
Fulvio Reggiori
Fulvio Reggiori University of Groningen
Vojo Deretic
Vojo Deretic University of New Mexico

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