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Chemistry

D-Index
68
Citations
12564
World Ranking
6724
National Ranking
150

Overview

Wilfred R. Hagen is affiliated with Delft University of Technology in the Netherlands. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a total of 15 publications. Within this broad field, they have contributed to subfields including Molecular Biology, Renewable Energy, Sustainability and the Environment, Inorganic Chemistry, Biophysics, and Materials Chemistry.

Their main topics of research cover areas such as Electron Spin Resonance Studies, Metalloenzymes and iron-sulfur proteins, Photosynthetic Processes and Mechanisms, Metal-Catalyzed Oxygenation Mechanisms, Lanthanide and Transition Metal Complexes, Hemoglobin structure and function, and Trace Elements in Health.

Wilfred R. Hagen has published several notable papers in various scientific venues. Some recent publications include:

  • Structure and function of the hybrid cluster protein, 2022, Coordination Chemistry Reviews
  • Very Low-Frequency Broadband Electron Paramagnetic Resonance Spectroscopy of Metalloproteins, 2021, The Journal of Physical Chemistry A
  • Iron-sulfur clusters as inhibitors and catalysts of viral replication, 2022, Nature Chemistry
  • Trinuclear copper biocatalytic center forms an active site of thiocyanate dehydrogenase, 2020, Proceedings of the National Academy of Sciences
  • Unique Biradical Intermediate in the Mechanism of the Heme Enzyme Chlorite Dismutase, 2021, ACS Catalysis

Their frequent co-authors include Peter-Leon Hagedoorn, Kourosh Honarmand Ebrahimi, Simone Ciofi-Baffoni, Yvain Nicolet, and Nick E. Le Brun. Collaboration with these scientists has been a regular aspect of their research outputs.

Wilfred R. Hagen's work has appeared most often in journals such as Molecules and International Journal of Molecular Sciences. Other publication venues include Nature Chemistry, Proceedings of the National Academy of Sciences, and Coordination Chemistry Reviews.

Best Publications

  • A low-spin iron with CN and CO as intrinsic ligands forms the core of the active site in [Fe]-hydrogenases.

    Antonio J. Pierik;Marco Hulstein;Wilfred R. Hagen;Simon P. J. Albracht

  • Unity in the biochemistry of the iron-storage proteins ferritin and bacterioferritin.

    Kourosh Honarmand Ebrahimi;Peter-Leon Hagedoorn;Wilfred R. Hagen

  • Purification and Characterization of (Per)Chlorate Reductase from the Chlorate-Respiring Strain GR-1

    S.W.M. Kengen;G.B. Rikken;W.R. Hagen;C.G. van Ginkel

  • Direct electron transfer of redox proteins at the bare glassy carbon electrode.

    Wilfred R. Hagen

  • Characterization of the Corrinoid Iron-Sulfur Protein Tetrachloroethene Reductive Dehalogenase of Dehalobacter restrictus

    Julien Maillard;Wolfram Schumacher;Francisco Vazquez;Christophe Regeard

  • Purification and molecular characterization of ortho-chlorophenol reductive dehalogenase, a key enzyme of halorespiration in Desulfitobacterium dehalogenans

    B.A. van de Pas;H. Smidt;W.R. Hagen;J. van der Oost

  • Redox properties of the iron‐sulfur clusters in activated Fe‐hydrogenase from Desulfovibrio vulgaris (Hildenborough)

    Antonio J. Pierik;Wilfred R. Hagen;Jan S. Redeker;Ronnie B. G. Wolbert

  • Similarities in the architecture of the active sites of Ni-hydrogenases and Fe-hydrogenases detected by means of infrared spectroscopy.

    T.M. van der Spek;A.F. Arendsen;R.P. Happe;S. Yun

  • The bioinorganic chemistry of tungsten

    Loes E. Bevers;Peter-Leon Hagedoorn;Wilfred R. Hagen

  • Redox properties and EPR spectroscopy of the P clusters of Azotobacter vinelandii MoFe protein

    Antonio J. Pierik;Hans Wassink;Huub Haaker;Wilfred R. Hagen

  • Redox chemistry of cobalamin and iron-sulfur cofactors in the tetrachloroethene reductase of Dehalobacter restrictus

    Wolfram Schumacher;Christof Holliger;Alexander J.B Zehnder;Wilfred R Hagen

  • S= 9/2 EPR signals are evidence against coupling between the siroheme and the Fe/S cluster prosthetic groups in Desulfovibrio vulgaris (Hildenborough) dissimilatory sulfite reductase

    Antonio J. Pierik;Wilfred R. Hagen

  • Biomolecular EPR spectroscopy

    Wilfred Raymond Hagen

  • Enzymes of hydrogen metabolism in Pyrococcus furiosus.

    Pedro J. Silva;Pedro J. Silva;Eyke C. D. van den Ban;Hans Wassink;Huub Haaker

  • EPR Spectroscopy of Iron—Sulfur Proteins

    Unknown

  • Metastable Fe/S clusters. The synthesis, electronic structure, and transformations of the [Fe6S6(L)6]3' clusters (L=Cl', Br', I', RS', RO') and the structure of [(C2H5)4N]3[Fe6S6Cl6]

    M. G. Kanatzidis;W. R. Hagen;W. R. Dunham;R. K. Lester

  • Two W-containing formate dehydrogenases (CO2-reductases) involved in syntrophic propionate oxidation by Syntrophobacter fumaroxidans.

    Frank A. M. de Bok;Peter-Leon Hagedoorn;Pedro J. Silva;Wilfred R. Hagen

  • Determination of the redox properties of the Rieske [2Fe-2S] cluster of bovine heart bc1 complex by direct electrochemistry of a water-soluble fragment.

    T.A. Link;W.R. Hagen;A.J. Pierik;C. Assmann

  • Crystal Structure of the Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus Furiosus

    Jana Tatur;Wilfred R. Hagen;Pedro M. Matias

  • The catalytic center of ferritin regulates iron storage via Fe(II)-Fe(III) displacement.

    Kourosh Honarmand Ebrahimi;Eckhard Bill;Peter-Leon Hagedoorn;Wilfred R Hagen

  • Purification and characterization of Desulfovibrio vulgaris (Hildenborough) hydrogenase expressed in Escherichia coli.

    Gerrit Voordouw;Wilfred R. Hagen;K. Margreet Krüse‐Wolters;Anita van Berkel‐Arts

  • Quantitative EPR of an S = 7/2 system in thionine-oxidized MoFe proteins of nitrogenase. A redefinition of the P-cluster concept.

    Wilfred R. Hagen;Hans Wassink;Robert R. Eady;Barry E. Smith

Frequent Co-Authors

Antonio J. Pierik
Antonio J. Pierik Technical University of Kaiserslautern
Alfons J. M. Stams
Alfons J. M. Stams Wageningen University & Research
Terrance E. Meyer
Terrance E. Meyer University of Arizona
Cees Veeger
Cees Veeger Wageningen University & Research
Mike S. M. Jetten
Mike S. M. Jetten Radboud University
David Leys
David Leys University of Manchester
Michael A. Cusanovich
Michael A. Cusanovich University of Arizona
Simon P. J. Albracht
Simon P. J. Albracht University of Amsterdam
Servé W. M. Kengen
Servé W. M. Kengen Wageningen University & Research
Alexander J. B. Zehnder
Alexander J. B. Zehnder Swiss Federal Institute of Aquatic Science and Technology

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