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Neuroscience

D-Index
55
Citations
10347
World Ranking
4739
National Ranking
398

Overview

Thomas Bast is affiliated with the Kork Epilepsy Center, Kehl-Kork in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader fields, their work focuses on Psychiatry and Mental health, Pediatrics, Perinatology and Child Health, Genetics, Cellular and Molecular Neuroscience, and Clinical Biochemistry.

The main topics of Thomas Bast's research include epilepsy research and treatment, pharmacological effects and toxicity studies, neuroscience and neuropharmacology research, metabolism and genetic disorders, genomics and rare diseases, genetics and neurodevelopmental disorders, as well as neonatal and fetal brain pathology.

They have published extensively in several specialized venues. The most frequent publication venues are Clinical Epileptology, Epilepsia, Zeitschrift für Epileptologie, Epilepsia Open, and the European Journal of Paediatric Neurology.

Some of their recent papers are:

  • GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture, 2023, Nature Genetics
  • 4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2-encephalopathy, 2021, Science Translational Medicine
  • Real-world data on cannabidiol treatment of various epilepsy subtypes: A retrospective, multicenter study, 2023, Epilepsia Open
  • Real-World Experience Treating Pediatric Epilepsy Patients With Cenobamate, 2022, Frontiers in Neurology
  • The Phenotypic Spectrum of PRRT2-Associated Paroxysmal Neurologic Disorders in Childhood, 2020, Biomedicines

Thomas Bast frequently collaborates with other researchers. Their most frequent coauthors include Susanne Schubert-Bast, Adam Strzelczyk, Steffen Syrbe, Gerhard Kurlemann, and Kerstin Alexandra Klotz.

Best Publications

  • Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

    Blumcke I;Spreafico R;Haaker G;Coras R

  • Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders.

    Markus Wolff;Katrine M Johannesen;Ulrike B S Hedrich;Silvia Masnada

  • The standardized EEG electrode array of the IFCN

    Margitta Seeck;Laurent Koessler;Thomas Bast;Frans Leijten

  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

    Bassel Abou-Khalil;Pauls Auce;Andreja Avbersek;Melanie Bahlo

  • Focal cortical dysplasias: surgical outcome in 67 patients in relation to histological subtypes and dual pathology.

    Susanne Fauser;Andreas Schulze-Bonhage;Juergen Honegger;Hans Carmona

  • Clinical characteristics in focal cortical dysplasia: a retrospective evaluation in a series of 120 patients.

    Susanne Fauser;Hans-Juergen Huppertz;Thomas Bast;Karl Strobl

  • EEG and MEG source analysis of single and averaged interictal spikes reveals intrinsic epileptogenicity in focal cortical dysplasia.

    Thomas Bast;Oezdin Oezkan;Sabine Rona;Christoph Stippich

  • Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway

    Gregory M. Enns;Vandana Shashi;Matthew Bainbridge;Michael J. Gambello

  • Multiple source analysis of interictal spikes: goals, requirements, and clinical value.

    Michael Scherg;Thomas Bast;Patrick Berg

  • Long-term seizure outcome in 211 patients with focal cortical dysplasia.

    Susanne Fauser;Charles Essang;Dirk‐Matthias Altenmüller;Anke Maren Staack

  • Benign infantile seizures and paroxysmal dyskinesia caused by an SCN8A mutation

    Elena Gardella;Felicitas Becker;Rikke S. Møller;Julian Schubert

  • Rasmussen encephalitis: incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins.

    Christian G. Bien;Henning Tiemeier;Robert Sassen;Stefan Kuczaty

  • Status epilepticus in children with Alpers' disease caused by POLG1 mutations: EEG and MRI features.

    Nicole I. Wolf;Shamima Rahman;Bernhard Schmitt;Jan-Willem Taanman

  • Clinical spectrum and genotype–phenotype associations of KCNA2-related encephalopathies

    Silvia Masnada;Ulrike B S Hedrich;Elena Gardella;Julian Schubert

  • Impaired slow wave sleep downscaling in encephalopathy with status epilepticus during sleep (ESES).

    Bigna K. Bölsterli;Bernhard Schmitt;Thomas Bast;Hanne Critelli

  • Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery

    Kim Boshuisen;Monique M. J. van Schooneveld;Cuno S. P. M. Uiterwaal;J. Helen Cross

  • Factors influencing surgical outcome in patients with focal cortical dysplasia

    Susanne Fauser;Thomas Bast;Dirk-Matthias Altenmüller;Jürgen Schulte-Mönting

  • Revised version of quality guidelines for presurgical epilepsy evaluation and surgical epilepsy therapy issued by the Austrian, German, and Swiss working group on presurgical epilepsy diagnosis and operative epilepsy treatment

    Felix Rosenow;Felix Rosenow;Thomas Bast;Thomas Czech;Martha Feucht

  • Seizure and cognitive outcomes of epilepsy surgery in infancy and early childhood

    Georgia Ramantani;Navah Ester Kadish;Karl Strobl;Armin Brandt

  • Focal cortical dysplasia: prevalence, clinical presentation and epilepsy in children and adults

    Unknown

  • Seizure control and developmental trajectories after hemispherotomy for refractory epilepsy in childhood and adolescence.

    Georgia Ramantani;Navah Ester Kadish;Armin Brandt;Karl Strobl

  • Effectiveness and Tolerability of Perampanel in Children and Adolescents with Refractory Epilepsies: First Experiences

    Anna Biró;Ulrich Stephani;Tiziana Tarallo;Thomas Bast

Frequent Co-Authors

Adam Strzelczyk
Adam Strzelczyk Goethe University Frankfurt
Gerhard Kluger
Gerhard Kluger Paracelsus Medical University
Andreas Schulze-Bonhage
Andreas Schulze-Bonhage University of Freiburg
Bernhard J. Steinhoff
Bernhard J. Steinhoff University of Göttingen
Felix Rosenow
Felix Rosenow Goethe University Frankfurt
Karl Martin Klein
Karl Martin Klein University of Calgary
Ulrich Stephani
Ulrich Stephani Kiel University
Josef Zentner
Josef Zentner University of Freiburg
Julia Jacobs
Julia Jacobs University of Calgary
Holger Lerche
Holger Lerche University of Tübingen

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