World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
54
Citations
9710
World Ranking
3984
National Ranking
1544

Overview

Thomas A. Ficht is affiliated with Texas A&M University in the United States. Their research focus lies primarily within biochemistry, genetics, and molecular biology, encompassing 24 published works in this broad field. Subfields of particular interest include molecular biology, small animals, immunology, epidemiology, and endocrinology.

The scientist's work addresses several key topics. These are:

  • Brucella: diagnosis, epidemiology, treatment
  • Immunotherapy and Immune Responses
  • Bacillus and Francisella bacterial research
  • Endoplasmic Reticulum Stress and Disease
  • Galectins and Cancer Biology
  • Bacteriophages and microbial interactions
  • Autophagy in Disease and Therapy

Thomas A. Ficht has contributed to multiple recent publications, including the following:

  • "If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella" (2023), published in Journal of Clinical Microbiology
  • "Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment" (2022), published in Journal for ImmunoTherapy of Cancer
  • "Vaccine Candidate Brucella melitensis 16M ΔvjbR Is Safe in a Pregnant Sheep Model and Confers Protection" (2020), published in mSphere
  • "Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense" (2022), published in eLife
  • "The candidate vaccine strain Brucella ovisabcBA is protective against Brucella melitensis infection in mice" (2020), published in Microbiology and Immunology

The venues where Thomas A. Ficht frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory), with 4 publications
  • Cell Host & Microbe, with 2 publications
  • npj Vaccines, with 2 publications
  • Journal of Clinical Microbiology
  • Journal for ImmunoTherapy of Cancer

Collaborations form an integral part of their research output. Frequent coauthors include:

  • Paul de Figueiredo (15 collaborations)
  • Allison C. Rice-Ficht (11 collaborations)
  • Qing-Ming Qin (8 collaborations)
  • Jianxun Song (7 collaborations)
  • Sankar P. Chaki (7 collaborations)

Best Publications

  • Evolution of Host Adaptation in Salmonella Enterica

    Andreas J. Bäumler;Renée M. Tsolis;Thomas A. Ficht;L. Garry Adams

  • Pathogenesis and immunobiology of brucellosis: review of Brucella-host interactions.

    Paul de Figueiredo;Paul de Figueiredo;Paul de Figueiredo;Thomas A. Ficht;Allison Rice-Ficht;Carlos A. Rossetti

  • Contribution of Salmonella typhimurium virulence factors to diarrheal disease in calves.

    Renée M. Tsolis;L. Garry Adams;Thomas A. Ficht;Andreas J. Bäumler

  • Identification of Genes Required for Chronic Persistence of Brucella abortus in Mice

    Priscilla C. Hong;Renée M. Tsolis;Thomas A. Ficht

  • Polymeric particles in vaccine delivery

    Allison C Rice-Ficht;Angela M Arenas-Gamboa;Angela M Arenas-Gamboa;Melissa M Kahl-McDonagh;Thomas A Ficht

  • Identification of a putative Salmonella enterica serotype typhimurium host range factor with homology to IpaH and YopM by signature-tagged mutagenesis.

    Renée M. Tsolis;Stacy M. Townsend;Edward A. Miao;Samuel I. Miller

  • Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival.

    Chris A. Allen;L. Garry Adams;Thomas A. Ficht

  • Of mice, calves, and men. Comparison of the mouse typhoid model with other Salmonella infections.

    Renee M Tsolis;R. A. Kingsley;S. M. Townsend;T. A. Ficht

  • Brucella-induced abortions and infection in bottlenose dolphins (Tursiops truncatus).

    Miller Wg;Adams Lg;Ficht Ta;Cheville Nf

  • Of Mice, Calves, and Men

    Renée M. Tsolis;Robert A. Kingsley;Stacy M. Townsend;Thomas A. Ficht

  • The spv genes on the Salmonella dublin virulence plasmid are required for severe enteritis and systemic infection in the natural host.

    S J Libby;L G Adams;T A Ficht;C Allen

  • Interruption of the cydB Locus in Brucella abortus Attenuates Intracellular Survival and Virulence in the Mouse Model of Infection

    Seema Endley;David McMurray;Thomas A. Ficht

  • Protein synthesis in Brucella abortus induced during macrophage infection.

    Jyhsiun Lin;T. A. Ficht

  • Pathogenesis of Brucella

    Laurie D. Smith;Thomas A. Ficht

  • Rapid and Sensitive Detection of Mycobacterium avium subsp. paratuberculosis in Bovine Milk and Feces by a Combination of Immunomagnetic Bead Separation-Conventional PCR and Real-Time PCR

    Sangeeta Khare;Thomas A. Ficht;Renato L. Santos;Juan Romano

  • Identification of a polymorphic nucleotide in oxyR specific for Mycobacterium bovis.

    S. Sreevatsan;P. Escalante;X. Pan;D. A. Gillies

  • Analysis of Ten Brucella Genomes Reveals Evidence for Horizontal Gene Transfer Despite a Preferred Intracellular Lifestyle

    Alice R. Wattam;Kelly P. Williams;Eric E. Snyder;Nalvo F. Almeida;Nalvo F. Almeida

  • Synergistic effect of mutations in invA and lpfC on the ability of Salmonella typhimurium to cause murine typhoid.

    Andreas J. Bäumler;Renée M. Tsolis;Peter J. Valentine;Thomas A. Ficht

  • DNA sequence and expression of the 36-kilodalton outer membrane protein gene of Brucella abortus.

    T A Ficht;S W Bearden;B A Sowa;L G Adams

  • The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice

    Gregory T. Robertson;Michael E. Kovach;Chris A. Allen;Thomas A. Ficht

  • Intracellular survival of Brucella: defining the link with persistence.

    Thomas A. Ficht

Frequent Co-Authors

L. Garry Adams
L. Garry Adams Texas A&M University
Renée M. Tsolis
Renée M. Tsolis University of California, Davis
Andreas J. Bäumler
Andreas J. Bäumler University of California, Davis
Roger Smith
Roger Smith University of Newcastle Australia
James E. Samuel
James E. Samuel Texas A&M University
Robert A. Kingsley
Robert A. Kingsley University of East Anglia
David N. McMurray
David N. McMurray Texas A&M University
Renato L. Santos
Renato L. Santos Universidade Federal de Minas Gerais
C. Roy
C. Roy Centre national de la recherche scientifique, CNRS
João C. Setubal
João C. Setubal Universidade de São Paulo

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