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Neuroscience

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94
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936
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502

Medicine

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Citations
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Overview

Sanjay Asthana is affiliated with the University of Wisconsin-Madison in the United States and is primarily engaged in research within the field of Medicine. Their work spans several subfields, including Physiology, Psychiatry and Mental Health, Molecular Biology, Radiology, Nuclear Medicine and Imaging, as well as Neurology.

The research topics Sanjay Asthana has focused on include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Advanced Neuroimaging Techniques and Applications
  • Health disparities and outcomes
  • Tryptophan and brain disorders
  • Gut microbiota and health
  • Metabolomics and Mass Spectrometry Studies

Their recent published papers illustrate a focus on neurodegenerative diseases, biomarkers, and brain imaging, including the following:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020) - Nature Communications
  • Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations (2021) - Communications Biology
  • An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuum (2020) - Alzheimer s & Dementia
  • Association of Neighborhood-Level Disadvantage With Cerebral and Hippocampal Volume (2020) - JAMA Neurology
  • Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts (2022) - Brain

Frequent publication venues for their work include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Alzheimer s Disease
  • Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
  • Scientific Reports

Sanjay Asthana has collaborated extensively with a set of frequent co-authors, notably:

  • Sterling C. Johnson
  • Cynthia M. Carlsson
  • Barbara B. Bendlin
  • Henrik Zetterberg
  • Kaj Blennow

This record demonstrates a sustained research focus on Alzheimer's disease, dementia, and associated neurobiological and biochemical mechanisms, employing a combination of biomarker discovery, neuroimaging, and epidemiological approaches. The presence of collaborations with prominent researchers also indicates active engagement in multidisciplinary studies within this domain.

Best Publications

  • Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Unknown

  • Gut microbiome alterations in Alzheimer's disease.

    Nicholas M. Vogt;Robert L. Kerby;Kimberly A. Dill-McFarland;Sandra J. Harding

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone: A Preliminary Study

    G. Stennis Watson;Brenna A. Cholerton;Mark A. Reger;Laura D. Baker

  • Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease The TEAM-AD VA Cooperative Randomized Trial

    Maurice W. Dysken;Mary Sano;Sanjay Asthana;Julia E. Vertrees

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • Testosterone supplementation improves spatial and verbal memory in healthy older men

    Monique M. Cherrier;S. Asthana;S. Plymate;L. Baker

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

    Jacob W. Vogel;Yasser Iturria-Medina;Olof T. Strandberg;Ruben Smith

  • Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS–Cognitive and Affective Study

    Carey E. Gleason;N. Maritza Dowling;Whitney Wharton;JoAnn A E Manson

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease

    Auriel A. Willette;Barbara B. Bendlin;Erika J. Starks;Alex C. Birdsill

  • The gut microbiota-derived metabolite trimethylamine N -oxide is elevated in Alzheimer’s disease

    Nicholas M. Vogt;Kymberleigh A. Romano;Kymberleigh A. Romano;Burcu F. Darst;Corinne D. Engelman

  • Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose.

    Suzanne Craft;Sanjay Asthana;John W. Newcomer;Charles W. Wilkinson

  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

    Unknown

  • Insulin increases CSF Aβ42 levels in normal older adults

    G. S. Watson;E. R. Peskind;S. Asthana;K. Purganan

  • High-dose estradiol improves cognition for women with AD Results of a randomized study

    S. Asthana;L. D. Baker;S. Craft;F. Z. Stanczyk

  • Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment

    Monique M. Cherrier;A. M. Matsumoto;J. K. Amory;S. Asthana

  • Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.

    Taylor W. Schmitz;R. Nathan Spreng;Michael W. Weiner;Paul Aisen

  • The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions.

    Sterling C. Johnson;Rebecca L. Koscik;Erin M. Jonaitis;Lindsay R. Clark

  • Insulin dose–response effects on memory and plasma amyloid precursor protein in Alzheimer’s disease: interactions with apolipoprotein E genotype

    Suzanne Craft;Suzanne Craft;Sanjay Asthana;Sanjay Asthana;David G. Cook;David G. Cook;Laura D. Baker;Laura D. Baker

  • Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease : results of a placebo-controlled, double-blind, pilot study

    Sanjay Asthana;Suzanne Craft;Laura D Baker;Murray A Raskind

  • Hyperinsulinemia Provokes Synchronous Increases in Central Inflammation and β-Amyloid in Normal Adults

    Mark A. Fishel;G. Stennis Watson;Thomas J. Montine;Qin Wang

  • Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone

    G. Stennis Watson;Brenna A. Cholerton;Mark A. Reger;Laura D. Baker

Frequent Co-Authors

Sterling C. Johnson
Sterling C. Johnson University of Wisconsin–Madison
Mark A. Sager
Mark A. Sager University of Wisconsin–Madison
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Kaj Blennow
Kaj Blennow University of Gothenburg
Ozioma C. Okonkwo
Ozioma C. Okonkwo University of Wisconsin–Madison
Rebecca L. Koscik
Rebecca L. Koscik University of Wisconsin–Madison
Bruce P. Hermann
Bruce P. Hermann University of Wisconsin–Madison
Suzanne Craft
Suzanne Craft Wake Forest University
Laura D. Baker
Laura D. Baker Wake Forest University
Andrew L. Alexander
Andrew L. Alexander University of Wisconsin–Madison

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