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Chemistry

D-Index
46
Citations
10726
World Ranking
15866
National Ranking
3968

Overview

Richard W. Vachet is affiliated with the University of Massachusetts Amherst in the United States. Their research primarily spans the fields of Chemistry and Biochemistry, Genetics and Molecular Biology, with a strong focus on spectroscopy and molecular biology techniques.

The scientist's work includes significant contributions in subfields such as Spectroscopy, Molecular Biology, Biomedical Engineering, Radiology, Nuclear Medicine and Imaging, and Materials Chemistry.

Key research topics covered by Richard W. Vachet include:

  • Mass Spectrometry Techniques and Applications
  • Advanced Proteomics Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Advanced Biosensing and Bioanalysis Techniques
  • Monoclonal and Polyclonal Antibodies Research
  • Analytical Chemistry Methods Development
  • Biotin and Related Studies

Among Richard W. Vachet's frequent collaborators are:

  • Zachary J. Kirsch
  • Vincent M. Rotello
  • Jeerapat Doungchawee
  • Patanachai Limpikirati
  • Xiao Pan

The scientist has published extensively, with a number of articles appearing in notable journals such as:

  • Analytical Chemistry
  • Journal of the American Society for Mass Spectrometry
  • The Analyst
  • ACS Nano
  • Biochemistry

Selected recent papers by Richard W. Vachet include:

  • Intracellular Activation of Bioorthogonal Nanozymes through Endosomal Proteolysis of the Protein Corona (2020, ACS Nano)
  • Thermally Gated Bio-orthogonal Nanozymes with Supramolecularly Confined Porphyrin Catalysts for Antimicrobial Uses (2020, Chem)
  • A Programmable Chemical Switch Based on Triggerable Michael Acceptors (2020, Chemical Science)
  • Bioorthogonal Nanozymes for Breast Cancer Imaging and Therapy (2023, Journal of Controlled Release)
  • Utilization of Hydrophobic Microenvironment Sensitivity in Diethylpyrocarbonate Labeling for Protein Structure Prediction (2021, Analytical Chemistry)

Best Publications

  • Alkanethiolate Gold Cluster Molecules with Core Diameters from 1.5 to 5.2 nm: Core and Monolayer Properties as a Function of Core Size

    Michael J. Hostetler;Julia E. Wingate;Chuan Jian Zhong;Jay E. Harris

  • The basics of mass spectrometry in the twenty-first century

    Gary L. Glish;Richard W. Vachet

  • Effect of Surface Charge on the Uptake and Distribution of Gold Nanoparticles in Four Plant Species

    Zheng-Jiang Zhu;Huanhua Wang;Bo Yan;Hao Zheng

  • Probing protein structure by amino acid‐specific covalent labeling and mass spectrometry

    Vanessa Leah Mendoza;Richard W. Vachet

  • Growth of organic thin films by the matrix assisted pulsed laser evaporation (MAPLE) technique

    A. Piqué;R.A. McGill;D.B. Chrisey;D. Leonhardt

  • Surface Charge Controls the Suborgan Biodistributions of Gold Nanoparticles

    Sukru Gokhan Elci;Ying Jiang;Bo Yan;Sung Tae Kim

  • Molecular analysis of chromium and cobalt-related toxicity

    Brian Scharf;Cristina C. Clement;Valerio Zolla;Giorgio Perino

  • Multiplexed Screening of Cellular Uptake of Gold Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry

    Zheng-Jiang Zhu;Partha S. Ghosh;Oscar R. Miranda;Richard W. Vachet

  • Antioxidant Mechanisms of Enzymatic Hydrolysates of Beta-Lactoglobulin in Food Lipid Dispersions

    Ryan J. Elias;Juma D. Bridgewater;Richard W. Vachet;Thaddao Waraho

  • Stability of quantum dots in live cells

    Zheng-Jiang Zhu;Yi-Cheun Yeh;Rui Tang;Bo Yan

  • Surface properties dictate uptake, distribution, excretion, and toxicity of nanoparticles in fish.

    Zheng-Jiang Zhu;Rachel Carboni;Michael J. Quercio;Bo Yan

  • Interaction between Oxide Nanoparticles and Biomolecules of the Bacterial Cell Envelope As Examined by Infrared Spectroscopy

    Wei Jiang;Kun Yang;Richard W Vachet;Baoshan Xing

  • Novel Peptide Dissociation: Gas-Phase Intramolecular Rearrangement of Internal Amino Acid Residues

    Richard W. Vachet;Barney M. Bishop;Bruce W. Erickson;Gary L. Glish

  • Protein surface mapping using diethylpyrocarbonate with mass spectrometric detection

    Vanessa Leah Mendoza;Richard W. Vachet

  • Covalent labeling-mass spectrometry with non-specific reagents for studying protein structure and interactions.

    Patanachai Limpikirati;Tianying Liu;Richard W. Vachet

  • Intracellular Activation of Bioorthogonal Nanozymes through Endosomal Proteolysis of the Protein Corona.

    Xianzhi Zhang;Yuanchang Liu;Sanjana Gopalakrishnan;Laura Castellanos-Garcia

  • Ion–molecule reactions in a quadrupole ion trap as a probe of the gas-phase structure of metal complexes

    Richard W. Vachet;Judith Ann R. Hartman;John H. Callahan

  • The interplay of monolayer structure and serum protein interactions on the cellular uptake of gold nanoparticles.

    Zheng-Jiang Zhu;Tamara Posati;Daniel F. Moyano;Rui Tang

  • Mixed monolayer-protected gold nanoclusters as selective peptide extraction agents for MALDI-MS analysis.

    Benjamin N. Y. Vanderpuije;Gang Han;Vincent M. Rotello;Richard W. Vachet

  • Multiplexed Imaging of Nanoparticles in Tissues Using Laser Desorption/Ionization Mass Spectrometry

    Bo Yan;Sung Tae Kim;Chang Soo Kim;Krishnendu Saha

  • Development of a methodology based on metal-catalyzed oxidation reactions and mass spectrometry to determine the metal binding sites in copper metalloproteins

    Jihyeon Lim;Richard W. Vachet

  • Transition metal-peptide binding studied by metal-catalyzed oxidation reactions and mass spectrometry.

    Juma D. Bridgewater;Jihyeon Lim;Richard W. Vachet

Frequent Co-Authors

Vincent M. Rotello
Vincent M. Rotello University of Massachusetts Amherst
Sankaran Thayumanavan
Sankaran Thayumanavan University of Massachusetts Amherst
Gary L. Glish
Gary L. Glish University of North Carolina at Chapel Hill
Zheng-Jiang Zhu
Zheng-Jiang Zhu Chinese Academy of Sciences
Singyuk Hou
Singyuk Hou Samsung (United States)
Alberto Piqué
Alberto Piqué United States Naval Research Laboratory
Douglas B. Chrisey
Douglas B. Chrisey Tulane University
Nathan C. Gianneschi
Nathan C. Gianneschi Northwestern University
Baoshan Xing
Baoshan Xing University of Massachusetts Amherst
Chuan-Jian Zhong
Chuan-Jian Zhong Binghamton University

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