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Biology and Biochemistry

D-Index
57
Citations
11736
World Ranking
13835
National Ranking
98

Overview

Petri Lehenkari is affiliated with Oulu University Hospital in Finland and has contributed extensively to the field of medicine, with a particular focus on rheumatology, surgery, biomedical engineering, radiology, nuclear medicine and imaging, and molecular biology. Their research primarily addresses osteoarthritis treatment and mechanisms, musculoskeletal synovial abnormalities and treatments, rheumatoid arthritis research and therapies, medical imaging and analysis, bone metabolism and diseases, bone health and treatments, as well as orthopaedic implants and arthroplasty.

Their published work frequently appears in journals such as Osteoarthritis and Cartilage, BMC Musculoskeletal Disorders, Inflammation, Scientific Reports, and Annals of Biomedical Engineering.

  • Osteoarthritis and Cartilage
  • BMC Musculoskeletal Disorders
  • Inflammation
  • Scientific Reports
  • Annals of Biomedical Engineering

Lehenkari has collaborated regularly with several researchers, including Sanna Palosaari, Mikko Finnilä, Antti Joukainen, Jaakko Niinimäki, and Heikki Kröger.

  • Sanna Palosaari
  • Mikko Finnilä
  • Antti Joukainen
  • Jaakko Niinimäki
  • Heikki Kröger

The following are some of their recent papers:

  • Metabolomics of Synovial Fluid and Infrapatellar Fat Pad in Patients with Osteoarthritis or Rheumatoid Arthritis, 2022, Inflammation
  • Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro-computed tomography, 2020, Osteoarthritis and Cartilage
  • Characterization of hyaluronan-coated extracellular vesicles in synovial fluid of patients with osteoarthritis and rheumatoid arthritis, 2021, BMC Musculoskeletal Disorders
  • A Straightforward Method for Adipocyte Size and Count Analysis Using Open-source Software QuPath, 2022, Adipocyte
  • Differential synovial tissue expression of TLRs in seropositive and seronegative rheumatoid arthritis: A preliminary report, 2020, Autoimmunity

Best Publications

  • Automatic Knee Osteoarthritis Diagnosis from Plain Radiographs: A Deep Learning-Based Approach

    Aleksei Tiulpin;Jérôme Thevenot;Esa Rahtu;Petri Lehenkari

  • Removal of osteoclast bone resorption products by transcytosis.

    Jari Salo;Petri Lehenkari;Mika Mulari;Kalervo Metsikkö

  • Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable, Adenine-Containing Metabolite

    Petri P. Lehenkari;Maarit Kellinsalmi;Juha P. Näpänkangas;Kari V. Ylitalo

  • A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.

    Hannu Mönkkönen;Seppo Auriola;Petri Lehenkari;Maarit Kellinsalmi

  • Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase.

    Jussi M. Halleen;Seija Räisänen;Jari J. Salo;Sakamuri V. Reddy

  • Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy.

    P.P. Lehenkari;M.A. Horton

  • In vitro comparison of clodronate, pamidronate and zoledronic acid effects on rat osteoclasts and human stem cell-derived osteoblasts.

    Maarit Kellinsalmi;Hannu Mönkkönen;Jukka Mönkkönen;Hannu-Ville Leskelä

  • N‐Glycolylneuraminic Acid Xenoantigen Contamination of Human Embryonic and Mesenchymal Stem Cells Is Substantially Reversible

    Annamari Heiskanen;Tero Satomaa;Sari Tiitinen;Anita Laitinen

  • Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis

    Seija R. Räisänen;Petri Lehenkari;Merja Tasanen;Paavo Rahkila

  • The mechanism of action of induced membranes in bone repair.

    Olli-Matti Aho;Petri Lehenkari;Jukka Ristiniemi;Siri Lehtonen

  • Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2

    P Lehenkari;T A Hentunen;T A Hentunen;T Laitala-Leinonen;J Tuukkanen

  • Adapting atomic force microscopy for cell biology.

    P.P Lehenkari;G.T Charras;A Nykänen;M.A Horton

  • Osteoblast recruitment from stem cells does not decrease by age at late adulthood.

    Hannu-Ville Leskelä;Juha Risteli;Juha Risteli;Salla Niskanen;Jussi Koivunen

  • Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors.

    Tanja Hakkarainen;Merja Särkioja;Petri Lehenkari;Susanna Miettinen

  • Behaviour of Nitinol in osteoblast-like ROS-17 cell cultures

    A Kapanen;J Ilvesaro;A Danilov;J Ryhänen

  • Atomic force microscopy can be used to mechanically stimulate osteoblasts and evaluate cellular strain distributions.

    G.T. Charras;P.P. Lehenkari;M.A. Horton

  • Estrogen Reduces the Depth of Resorption Pits by Disturbing the Organic Bone Matrix Degradation Activity of Mature Osteoclasts

    Vilhelmiina Parikka;Vilhelmiina Parikka;Petri Lehenkari;Mirja-Liisa Sassi;Jussi Halleen

  • The effects of bisphosphonates on the resorption cycle of isolated osteoclasts

    K. Selander;P. Lehenkari;H. K. Väänänen

  • HIF-1α is upregulated in human mesenchymal stem cells.

    Sami Palomäki;Mika Pietilä;Saara Laitinen;Juha Pesälä

  • Carbonic anhydrase III protects cells from hydrogen peroxide induced apoptosis

    S. Räisänen;P. Lehenkari;M. Tasanen;P. Härkönen

Frequent Co-Authors

Simo Saarakkala
Simo Saarakkala University of Oulu
Tuomo J. Karttunen
Tuomo J. Karttunen Oulu University Hospital
Tuula Salo
Tuula Salo University of Helsinki
Juha Risteli
Juha Risteli University of Oulu
Heikki Kröger
Heikki Kröger University of Eastern Finland
Frank W. Roemer
Frank W. Roemer University of Erlangen-Nuremberg
Ilmo E. Hassinen
Ilmo E. Hassinen University of Oulu
Guillaume Charras
Guillaume Charras London Centre for Nanotechnology
Ylermi Soini
Ylermi Soini University of Eastern Finland
Pirkko Härkönen
Pirkko Härkönen University of Turku

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