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Biology and Biochemistry

D-Index
53
Citations
26604
World Ranking
15884
National Ranking
349

Overview

Pascual Sanz is affiliated with the Spanish National Research Council in Spain. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on several specialized subfields including Rheumatology, Molecular Biology, Neurology, Genetics, and Physiology.

The scientist has contributed extensively to topics such as Glycogen Storage Diseases and Myoclonus, Genetics and Neurodevelopmental Disorders, Protein Tyrosine Phosphatases, Autoimmune Neurological Disorders and Treatments, Lysosomal Storage Disorders Research, Neurological disorders and treatments, and Neuroinflammation and Neurodegeneration Mechanisms.

Pascual Sanz's publication record includes a selection of recent papers:

  • Reactive Glia Inflammatory Signaling Pathways and Epilepsy (2020) published in International Journal of Molecular Sciences
  • Neuroinflammation and Epilepsy: From Pathophysiology to Therapies Based on Repurposing Drugs (2024) published in International Journal of Molecular Sciences
  • Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora Disease (2021) published in International Journal of Molecular Sciences

Frequent co-authors collaborating with Pascual Sanz include:

  • María Adelaida García-Gimeno
  • José M. Serratosa
  • Rosa Viana
  • Mireia Moreno-Estellés
  • Ángela Campos-Rodríguez

The scientist's work has been published predominantly in several key venues:

  • International Journal of Molecular Sciences (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 publications)
  • Molecular Neurobiology (3 publications)
  • Epilepsy & Behavior (2 publications)
  • Neurobiology of Disease (2 publications)

This research profile reflects a focus on neurological and molecular mechanisms underlying diseases such as epilepsy and Lafora disease, emphasizing inflammation, neurodegeneration, and genetic factors. The scientist's studies have contributed to understanding inflammatory signaling pathways and therapeutic repurposing strategies.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase.

    Pascual Sanz;Geoffrey R. Alms;Timothy A. J. Haystead;Marian Carlson

  • A 13C Nuclear Magnetic Resonance Investigation of the Metabolism of Leucine to Isoamyl Alcohol in Saccharomyces cerevisiae

    J. R. Dickinson;M. M. Lanterman;D. J. Danner;B. M. Pearson

  • Severe Persistent Hyperinsulinemic Hypoglycemia due to a De Novo Glucokinase Mutation

    Antonio L. Cuesta-Muñoz;Hanna Huopio;Timo Otonkoski;Juan M. Gomez-Zumaquero

  • Laforin, the most common protein mutated in Lafora disease, regulates autophagy

    Carmen Aguado;Sovan Sarkar;Viktor I. Korolchuk;Olga Criado

  • Frataxin interacts functionally with mitochondrial electron transport chain proteins

    Pilar González-Cabo;Rafael P. Vázquez-Manrique;M. Adelaida García-Gimeno;Pascual Sanz

  • Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway

    Maria del Carmen Solaz-Fuster;José Vicente Gimeno-Alcañiz;Susana Ros;Maria Elena Fernandez-Sanchez

  • Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

    Olga Criado;Carmen Aguado;Javier Gayarre;Lara Duran-Trio

  • Engineering baker's yeast: room for improvement.

    Francisca Randez-Gil;Pascual Sanz;Jose A Prieto

  • Carbon source-dependent phosphorylation of hexokinase PII and its role in the glucose-signaling response in yeast.

    Francisca Randez-Gil;Pascual Sanz;Karl-Dieter Entian;Jose Antonio Prieto

  • Laforin, the dual-phosphatase responsible for Lafora disease, interacts with R5 (PTG), a regulatory subunit of protein phosphatase-1 that enhances glycogen accumulation

    Maria Elena Fernández-Sánchez;Olga Criado-García;Karen E. Heath;Belén García-Fojeda

  • Convergence of the Target of Rapamycin and the Snf1 Protein Kinase Pathways in the Regulation of the Subcellular Localization of Msn2, a Transcriptional Activator of STRE (Stress Response Element)-regulated Genes

    Isabel Mayordomo;Francisco Estruch;Pascual Sanz

  • Hexokinase PII has a double cytosolic‐nuclear localisation in Saccharomyces cerevisiae

    Francisca Randez-Gil;Pilar Herrero;Pascual Sanz;José Antonio Prieto

  • Reactive Glia Inflammatory Signaling Pathways and Epilepsy.

    Pascual Sanz;Maria Adelaida Garcia-Gimeno

  • AMPKα1-LDH pathway regulates muscle stem cell self-renewal by controlling metabolic homeostasis

    Marine Theret;Linda Gsaier;Linda Gsaier;Linda Gsaier;Bethany Schaffer;Gaëtan Juban;Gaëtan Juban;Gaëtan Juban

  • AMP-Activated Protein Kinase: Structure and Regulation

    Pascual Sanz

  • Large Islets, Beta-Cell Proliferation, and a Glucokinase Mutation

    Sameer Kassem;Sonal Bhandari;Pablo Rodríguez-Bada;Roja Motaghedi

  • A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism

    Daniel Moreno;Erwin Knecht;Benoit Viollet;Benoit Viollet;Pascual Sanz

  • Lafora bodies and neurological defects in malin-deficient mice correlate with impaired

    Olga Criado;Carmen Aguado;Javier Gayarre;Lara Duran-Trio

Frequent Co-Authors

Erwin Knecht
Erwin Knecht University of Valencia
Santiago Rodríguez de Córdoba
Santiago Rodríguez de Córdoba Spanish National Research Council
José M. Serratosa
José M. Serratosa Hospital Universitario Fundación Jiménez Díaz
Federico V. Pallardó
Federico V. Pallardó University of Valencia
Rafael Sentandreu
Rafael Sentandreu University of Valencia
Benoit Viollet
Benoit Viollet Institut Cochin
Sheng Li
Sheng Li University of California, San Diego
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Marian Carlson
Marian Carlson Howard Hughes Medical Institute

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