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Paola Defilippi

Paola Defilippi

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
11673
World Ranking
17029
National Ranking
542

Overview

Paola Defilippi is affiliated with the University of Turin in Italy. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, Defilippi has contributed extensively, with 26 publications related to Medicine and 23 in Biochemistry, Genetics and Molecular Biology.

The scientist's work focuses on several subfields, including Molecular Biology, Cancer Research, Infectious Diseases, Immunology, and Oncology. In these areas, their investigations emphasize molecular mechanisms and disease pathology.

Key research topics explored by Defilippi include:

  • Computational Drug Discovery Methods
  • Cell Adhesion Molecules Research
  • Immune cells in cancer
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Erythrocyte Function and Pathophysiology
  • Pancreatic function and diabetes

The scientist has published in several notable venues, with repeated contributions to:

  • Cellular and Molecular Life Sciences
  • Frontiers in Oncology
  • Oncogene
  • BioMed Research International
  • Acta Neuropathologica Communications

Among recent research papers authored or co-authored by Paola Defilippi are:

  • The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy (2021), published in Frontiers in Oncology
  • STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts (2022), published in Oncogene
  • Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues (2020), published in BioMed Research International
  • Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis (2021), published in Acta Neuropathologica Communications
  • miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression (2022), published in Cellular and Molecular Life Sciences

Frequent collaborators in Defilippi's research include Vincenzo Salemme, Giorgia Centonze, Emilia Turco, Dora Natalini, and Daniela Taverna, reflecting a network of scientific partnerships supporting multidisciplinary studies.

Best Publications

  • Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion‐dependent cell survival

    Laura Moro;Mascia Venturino;Chiarella Bozzo;Lorenzo Silengo

  • Role of αvβ3 integrin in the activation of vascular endothelial growth factor receptor‐2

    Raffaella Soldi;Stefania Mitola;Marina Strasly;Paola Defilippi

  • Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate.

    Federico Bussolino;Ji Ming Wang;Paola Defilippi;F. Turrini

  • Dynamic Microtubules Regulate Dendritic Spine Morphology and Synaptic Plasticity

    Jacek Jaworski;Lukas C. Kapitein;Susana Montenegro Gouveia;Bjorn R. Dortland

  • Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche

    Maria Felice Brizzi;Guido Tarone;Paola Defilippi

  • Integrin-induced Epidermal Growth Factor (EGF) Receptor Activation Requires c-Src and p130Cas and Leads to Phosphorylation of Specific EGF Receptor Tyrosines

    Laura Moro;Laura Dolce;Sara Cabodi;Elena Bergatto

  • p130Cas: a versatile scaffold in signaling networks.

    Paola Defilippi;Paola Di Stefano;Sara Cabodi

  • Integrin signalling adaptors: not only figurants in the cancer story

    Sara Cabodi;Maria del Pilar Camacho-Leal;Paola Di Stefano;Paola Defilippi

  • The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase

    Marco Sciacovelli;Giulia Guzzo;Virginia Morello;Christian Frezza

  • Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses

    S. Cabodi;L. Moro;E. Bergatto;E. Boeri Erba

  • Actin cytoskeleton organization in response to integrin-mediated adhesion.

    Paola Defilippi;Cristina Olivo;Mascia Venturino;Laura Dolce

  • The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy.

    Vincenzo Salemme;Giorgia Centonze;Federica Cavallo;Paola Defilippi

  • Differential distribution and modulation of expression of alpha 1/beta 1 integrin on human endothelial cells.

    P Defilippi;V van Hinsbergh;A Bertolotto;P Rossino

  • Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells.

    P Defilippi;G Truffa;G Stefanuto;F Altruda

  • Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

    Alessia Cherubini;Giovanna Hofmann;Serena Pillozzi;Leonardo Guasti

  • β1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells

    V Morello;S Cabodi;S Sigismund;M P Camacho-Leal

  • Integrins and Signal Transduction

    Sara Cabodi;Paola Di Stefano;Maria del Pilar Camacho Leal;Agata Tinnirello

  • p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells.

    Sara Cabodi;Laura Moro;Germano Baj;Monica Smeriglio

  • p130Cas as a New Regulator of Mammary Epithelial Cell Proliferation, Survival, and HER2-Neu Oncogene–Dependent Breast Tumorigenesis

    Sara Cabodi;Agata Tinnirello;Paola Di Stefano;Brigitte Bisarò

  • Up-regulation of the integrin alpha 1/beta 1 in human neuroblastoma cells differentiated by retinoic acid: correlation with increased neurite outgrowth response to laminin.

    P Rossino;P Defilippi;L Silengo;G Tarone

Frequent Co-Authors

Lorenzo Silengo
Lorenzo Silengo University of Turin
Guido Tarone
Guido Tarone University of Turin
Paolo Provero
Paolo Provero University of Turin
Anna Sapino
Anna Sapino University of Turin
Michela Matteoli
Michela Matteoli Humanitas University
Federica Cavallo
Federica Cavallo University of Turin
Federico Bussolino
Federico Bussolino University of Turin
Fiorella Altruda
Fiorella Altruda University of Turin
Chiara Riganti
Chiara Riganti University of Turin
Annarosa Arcangeli
Annarosa Arcangeli University of Florence

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