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Neuroscience

D-Index
36
Citations
7378
World Ranking
8923
National Ranking
3776

Overview

Noboru Hiroi is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research spans a range of topics primarily within molecular biology, genetics, and neurodevelopmental disorders, frequently contributing to several intersecting fields of study.

Hiroi's work encompasses main topics such as:

  • Congenital heart defects research
  • Genetics and neurodevelopmental disorders
  • Infant health and development
  • Neuroendocrine regulation and behavior
  • Coronary artery anomalies
  • Autism spectrum disorder research
  • Epigenetics and DNA methylation

The scientist has published research in several publication venues, with notable frequency in:

  • Biological Psychiatry
  • Molecular Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genomic Psychiatry
  • Research Square

Hiroi's recent papers reflect a focus on neuropsychiatric and developmental biology issues. Selected recent publications include:

  • "Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior," 2024, Molecular Psychiatry
  • "Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice," 2021, Molecular Psychiatry
  • "Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism," 2020, Developmental Psychobiology
  • "Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ," 2020, Cells
  • "Computational identification of variables in neonatal vocalizations predictive for postpubertal social behaviors in a mouse model of 16p11.2 deletion," 2021, Molecular Psychiatry

Their subfields of study emphasize molecular biology and genetics, accompanied by research in pharmacy, social psychology, and pulmonary and respiratory medicine.

Frequent co-authors in Hiroi's publications include individuals such as Anissa Abi-Dargham, Deanna M. Barch, and Edward T. Bullmore. Collaborations have also involved researchers affiliated with locations such as New York and St Louis.

Best Publications

  • Regulation of Cocaine Reward by CREB

    William A. Carlezon;Johannes Thome;Valerie G. Olson;Sarah B. Lane-Ladd

  • DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission

    A. A. Fienberg;N. Hiroi;Paul G Mermelstein;W. J. Song

  • Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

    Ming Xu;Rosario Moratalla;Lisa H. Gold;Noboru Hiroi

  • Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine

    Melissa T. Berhow;Noboru Hiroi;Eric J. Nestler

  • Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor.

    Beatriz A. Rocha;Kimberly Scearce-Levie;José J. Lucas;José J. Lucas;Noboru Hiroi;Noboru Hiroi

  • FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects.

    Noboru Hiroi;Jennifer R. Brown;Colin N. Haile;Hong Ye

  • The lateral nucleus of the amygdala mediates expression of the amphetamine-produced conditioned place preference

    Noboru Hiroi;Norman M. White

  • The amphetamine conditioned place preference: differential involvement of dopamine receptor subtypes and two dopaminergic terminal areas.

    Noboru Hiroi;Norman M. White

  • Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments.

    Jingshan Chen;H. E. Nye;M. B. Kelz;N. Hiroi

  • Place conditioning with dopamine D1 and D2 agonists injected peripherally or into nucleus accumbens.

    Norman M. White;Mark G. Packard;Noboru Hiroi

  • Genetic susceptibility to substance dependence

    N Hiroi;S Agatsuma

  • Essential Role of the fosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures

    Noboru Hiroi;Gerard J. Marek;Jennifer R. Brown;Hong Ye

  • Preferential localization of self-stimulation sites in striosomes/patches in the rat striatum

    Norman M. White;Noboru Hiroi;Noboru Hiroi

  • Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders

    N Hiroi;T Takahashi;A Hishimoto;T Izumi

  • Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum.

    Noboru Hiroi;Ann M. Graybiel

  • Neurobiological perspective of 22q11.2 deletion syndrome.

    Janneke R Zinkstok;Erik Boot;Anne S Bassett;Noboru Hiroi

  • Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs.

    Joshua B. Atkins;Jennifer Chlan-Fourney;Heather E. Nye;Noboru Hiroi

  • Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats.

    Colin N. Haile;Noboru Hiroi;Eric J. Nestler;Therese A. Kosten

  • Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model

    Takeshi Hiramoto;Gina Kang;Go Suzuki;Yasushi Satoh

  • Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.

    Noboru Hiroi;Allen A. Fienberg;Colin N. Haile;Mario Alburges

  • Structure and function of neonatal social communication in a genetic mouse model of autism.

    Tomohisa Takahashi;Shota Okabe;Pilib Ó Broin;Akira Nishi;Akira Nishi

Frequent Co-Authors

Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Norman M. White
Norman M. White McGill University
Rosario Moratalla
Rosario Moratalla Spanish National Research Council
Raju Kucherlapati
Raju Kucherlapati Harvard University
Steven E. Hyman
Steven E. Hyman Harvard University
Ronald S. Duman
Ronald S. Duman Yale University
Allen A. Fienberg
Allen A. Fienberg Rockefeller University
Bernice E. Morrow
Bernice E. Morrow Albert Einstein College of Medicine
William A. Carlezon
William A. Carlezon Harvard University
Mark A. Geyer
Mark A. Geyer University of California, San Diego

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Related Online Degrees & Career Pathways

If you’re passionate about neuroscience but interested in broader mental health or social science fields, several online degree options might align with your goals. Many students pair neuroscience studies with degrees like psychology, social work, or marriage and family therapy, opening doors to diverse career paths in healthcare, research, and counseling.

Pursuing an affordable online psychology masters can strengthen your knowledge of human behavior and mental processes, essential for roles in clinical psychology or research. Similarly, it’s possible to study psychology online at the undergraduate level, making this a flexible and accessible complement to your neuroscience expertise.

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