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Motokazu Uchigashima

Motokazu Uchigashima

D-Index & Metrics

Neuroscience

D-Index
36
Citations
7029
World Ranking
8935
National Ranking
327

Overview

Motokazu Uchigashima is affiliated with Niigata University in Japan and specializes primarily in neuroscience and biochemistry, genetics, and molecular biology. Their research contributions span cellular and molecular neuroscience, molecular biology, and materials chemistry, with additional involvement in neurology and genetics.

The main topics addressed in their work include neuroscience and neuropharmacology research, photochromic and fluorescence chemistry, photoreceptor and optogenetics research, retinal development and disorders, genetics and neurodevelopmental disorders, neuroinflammation and neurodegeneration mechanisms, and receptor mechanisms and signaling.

Uchigashima has published several papers in respected scientific journals. Some recent publications include:

  • General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process, 2022, Journal of the American Chemical Society
  • Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction, 2021, Frontiers in Molecular Neuroscience
  • Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus, 2020, Journal of Biological Chemistry
  • Specific Neuroligin3-αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus, 2020, eLife
  • Enhanced Retrieval of Taste Associative Memory by Chemogenetic Activation of Locus Coeruleus Norepinephrine Neurons, 2020, Journal of Neuroscience

The frequent publication venues for Uchigashima's work include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Journal of the American Chemical Society, Frontiers in Molecular Neuroscience, and Journal of Biological Chemistry.

Collaborations have been a significant aspect of their research. Frequent co-authors include Takayasu Mikuni, Kensuke Futai, Amy Cheung, Masahiko Watanabe, and Takuya Watanabe.

Best Publications

  • Endocannabinoid-Mediated Control of Synaptic Transmission

    Masanobu Kano;Takako Ohno-Shosaku;Yuki Hashimotodani;Motokazu Uchigashima

  • The Endocannabinoid 2-Arachidonoylglycerol Produced by Diacylglycerol Lipase α Mediates Retrograde Suppression of Synaptic Transmission

    Asami Tanimura;Maya Yamazaki;Yuki Hashimotodani;Motokazu Uchigashima

  • Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor.

    Takayuki Yoshida;Masahiro Fukaya;Motokazu Uchigashima;Eriko Miura

  • Subcellular arrangement of molecules for 2-arachidonoyl-glycerol-mediated retrograde signaling and its physiological contribution to synaptic modulation in the striatum

    Motokazu Uchigashima;Madoka Narushima;Masahiro Fukaya;Istvan Katona

  • Monitoring and Updating of Action Selection for Goal-Directed Behavior through the Striatal Direct and Indirect Pathways.

    Satoshi Nonomura;Kayo Nishizawa;Yutaka Sakai;Yasuo Kawaguchi

  • Three Types of Neurochemical Projection from the Bed Nucleus of the Stria Terminalis to the Ventral Tegmental Area in Adult Mice

    Takehiro Kudo;Motokazu Uchigashima;Taisuke Miyazaki;Kohtarou Konno

  • Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

    Keiko Matsuda;Timotheus Budisantoso;Nikolaos Mitakidis;Yuki Sugaya

  • Tonic Enhancement of Endocannabinoid-Mediated Retrograde Suppression of Inhibition by Cholinergic Interneuron Activity in the Striatum

    Madoka Narushima;Motokazu Uchigashima;Masahiro Fukaya;Minoru Matsui

  • Retrograde Semaphorin Signaling Regulates Synapse Elimination in the Developing Mouse Brain

    Naofumi Uesaka;Motokazu Uchigashima;Takayasu Mikuni;Takanobu Nakazawa

  • Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures

    Motokazu Uchigashima;Toshihisa Ohtsuka;Kazuto Kobayashi;Masahiko Watanabe

  • Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus

    Takayuki Yoshida;Motokazu Uchigashima;Miwako Yamasaki;Istvan Katona

  • Ventrolateral Striatal Medium Spiny Neurons Positively Regulate Food-Incentive, Goal-Directed Behavior Independently of D1 and D2 Selectivity.

    Akiyo Natsubori;Akiyo Natsubori;Iku Tsutsui-Kimura;Hiroshi Nishida;Youcef Bouchekioua

  • Depolarization‐induced suppression of inhibition mediated by endocannabinoids at synapses from fast‐spiking interneurons to medium spiny neurons in the striatum

    Madoka Narushima;Madoka Narushima;Motokazu Uchigashima;Kouichi Hashimoto;Masahiko Watanabe

  • Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction

    Unknown

  • Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus.

    Motokazu Uchigashima;Maya Yamazaki;Miwako Yamasaki;Asami Tanimura

  • Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway.

    César Quiroz;Rafael Luján;Motokazu Uchigashima;Ana Patrícia Simoes

  • Cytochemical and cytological properties of perineuronal oligodendrocytes in the mouse cortex

    Chihiro Takasaki;Miwako Yamasaki;Motokazu Uchigashima;Kohtarou Konno

  • Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo

    Taku Nagai;Taku Nagai;Shinichi Nakamuta;Shinichi Nakamuta;Keisuke Kuroda;Keisuke Kuroda;Sakura Nakauchi;Sakura Nakauchi

  • Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse elimination.

    Ryoichi Ichikawa;Kouichi Hashimoto;Taisuke Miyazaki;Motokazu Uchigashima

  • Selective Neural Pathway Targeting Reveals Key Roles of Thalamostriatal Projection in the Control of Visual Discrimination

    Shigeki Kato;Masahito Kuramochi;Kenta Kobayashi;Ryoji Fukabori

  • Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures

    Yuki Sugaya;Maya Yamazaki;Motokazu Uchigashima;Kenta Kobayashi

Frequent Co-Authors

Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Masanobu Kano
Masanobu Kano University of Tokyo
Miwako Yamasaki
Miwako Yamasaki Hokkaido University
Kouichi Hashimoto
Kouichi Hashimoto Hiroshima University
Kenji Sakimura
Kenji Sakimura Niigata University
Taisuke Miyazaki
Taisuke Miyazaki Hokkaido University
Masahiro Fukaya
Masahiro Fukaya Kitasato University
Manabu Abe
Manabu Abe Niigata University
István Katona
István Katona Hungarian Academy of Sciences
Hirotaka Onoe
Hirotaka Onoe Kyoto University

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