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Biology and Biochemistry

D-Index
76
Citations
17854
World Ranking
5117
National Ranking
375

Overview

Jörg Gromoll is affiliated with the University of Münster in Germany and has contributed extensively to research in the fields of biochemistry, genetics, and molecular biology, with a strong focus on medicine. Their research portfolio encompasses 39 publications in biochemistry, genetics, and molecular biology, alongside 33 publications in medicine.

Their main research subfields include reproductive medicine and molecular biology, each with 20 publications, as well as genetics with 19 publications. Additional areas of study cover surgery and endocrinology, diabetes, and metabolism. The core topics of their work revolve around sperm and testicular function, genetic and clinical aspects of sex determination and chromosomal abnormalities, and sexual differentiation and disorders. Their research also extends to testicular diseases and treatments, genomics and chromatin dynamics, molecular biology techniques and applications, and hormonal and reproductive studies.

Jörg Gromoll has authored several recent papers, including:

  • A germ cell-specific ageing pattern in otherwise healthy men, 2020, Aging Cell
  • Deep learning predicts therapy-relevant genetics in acute myeloid leukemia from Pappenheim-stained bone marrow smears, 2023, Blood Advances
  • Testicular Microlithiasis Is Associated with Impaired Spermatogenesis in Patients with Unexplained Infertility, 2020, Urologia Internationalis
  • Transcriptome analyses in infertile men reveal germ cell-specific expression and splicing patterns, 2022, Life Science Alliance
  • The Male Fertility Gene Atlas: a web tool for collecting and integrating OMICS data in the context of male infertility, 2020, Human Reproduction

Their frequent co-authors include Sabine Kliesch, Frank Tüttelmann, Sandra Laurentino, Martin Dugas, and Joachim Wistuba. Collaborative efforts with these researchers have contributed to advancing knowledge in reproductive medicine and related disciplines.

Jörg Gromoll has published multiple works in notable scientific venues. Among the most frequent publication venues are:

  • Human Reproduction
  • Andrology
  • The Journal of Clinical Endocrinology & Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrine Abstracts

Best Publications

  • MUTATION IN THE FOLLICLE-STIMULATING HORMONE RECEPTOR GENE CAUSES HEREDITARY HYPERGONADOTROPIC OVARIAN FAILURE

    Kristiina Aittomäki;Kristiina Aittomäki;JoséLuis Dieguez Lucena;JoséLuis Dieguez Lucena;Pirjo Pakarinen;Pertti Sistonen

  • The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology.

    Manuela Simoni;Jörg Gromoll;Eberhard Nieschlag

  • Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype

    Maritza Perez Mayorga;Jörg Gromoll;Hermann M. Behre;Claudia Gassner

  • Derivation of male germ cells from bone marrow stem cells

    Karim Nayernia;Jae Ho Lee;Nadja Drusenheimer;Jessica Nolte

  • Isolation and Characterization of Pluripotent Human Spermatogonial Stem Cell-Derived Cells

    Nina Kossack;Nina Kossack;Juanito Meneses;Shai Shefi;Shai Shefi;Ha Nam Nguyen

  • An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man.

    J Gromoll;Manuela Simoni;E. Nieschlag

  • Deletion of azoospermia factor a (AZFa) region of human Y chromosome caused by recombination between HERV15 proviruses

    Chao Sun;Helen Skaletsky;Steve Rozen;Jörg Gromoll

  • X-Chromosome Inactivation Patterns and Androgen Receptor Functionality Influence Phenotype and Social Characteristics as Well as Pharmacogenetics of Testosterone Therapy in Klinefelter Patients

    Michael Zitzmann;Marion Depenbusch;Jörg Gromoll;Eberhard Nieschlag

  • Screening for Deletions of the Y Chromosome Involving the DAZ (Deleted in Azoospermia) Gene in Azoospermia and Severe Oligozoospermia

    M. Simoni;J. Gromoll;B. Dworniczak;C. Rolf

  • Clinical, endocrinological, and epigenetic features of the 46,XX male syndrome, compared with 47,XXY Klinefelter patients.

    Elena Vorona;Michael Zitzmann;Jörg Gromoll;Andreas N Schüring

  • Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1.

    A. Poplinski;F. Tüttelmann;D. Kanber;B. Horsthemke

  • Isoforms and single nucleotide polymorphisms of the FSH receptor gene: implications for human reproduction

    M Simoni;E Nieschlag;J Gromoll

  • Mutational analysis of the follicle-stimulating hormone (FSH) receptor in normal and infertile men: identification and characterization of two discrete FSH receptor isoforms.

    Manuela Simoni;Jörg Gromoll;Wolfgang Höppner;Axel Kamischke

  • Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH.

    Jörg Gromoll;Urs Eiholzer;Eberhard Nieschlag;Manuela Simoni

  • Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation.

    Hermann M Behre;Robert R Greb;Andrea Mempel;Barbara Sonntag

  • The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men

    M. Zitzmann;J. Gromoll;A. von Eckardstein;E. Nieschlag

  • Clinical consequences of microdeletions of the Y chromosome: the extended Münster experience

    Manuela Simoni;Frank Tüttelmann;Jörg Gromoll;Eberhard Nieschlag

  • A common single nucleotide polymorphism in exon 10 of the human follicle stimulating hormone receptor is a major determinant of length and hormonal dynamics of the menstrual cycle.

    Rr Greb;K Grieshaber;J Gromoll;B Sonntag

  • Testosterone Replacement Effectively Inhibits the Development of Experimental Autoimmune Orchitis in Rats: Evidence for a Direct Role of Testosterone on Regulatory T Cell Expansion

    Monika Fijak;Eva Schneider;Jörg Klug;Sudhanshu Bhushan

  • Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis.

    K. Hucklenbroich;J. Gromoll;M. Heinrich;C. Hohoff

Frequent Co-Authors

Eberhard Nieschlag
Eberhard Nieschlag University of Münster
Manuela Simoni
Manuela Simoni University of Modena and Reggio Emilia
Bernhard Horsthemke
Bernhard Horsthemke University of Duisburg-Essen
Miles F. Wilkinson
Miles F. Wilkinson University of California, San Diego
Karin Buiting
Karin Buiting University of Duisburg-Essen
Ilpo Huhtaniemi
Ilpo Huhtaniemi Imperial College London
Sven Diederichs
Sven Diederichs German Cancer Research Center
Martin Dugas
Martin Dugas Heidelberg University
Thomas Haaf
Thomas Haaf University of Würzburg

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