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Neuroscience

D-Index
39
Citations
4546
World Ranking
8405
National Ranking
133

Overview

Haiyun Xu is affiliated with Shantou University in China and conducts research primarily in the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work covers various subfields including Molecular Biology, Neurology, Physiology, Developmental Neuroscience, and Biological Psychiatry.

Xu's research spans several major topics, notably Neuroinflammation and Neurodegeneration Mechanisms, Tryptophan and brain disorders, Neurogenesis and neuroplasticity mechanisms, Stress Responses and Cortisol, Neuroendocrine regulation and behavior, COVID-19 and Mental Health, and broader Mental Health Research Topics.

The researcher has a record of recent publications that demonstrate a focus on neuropsychiatric disorders, neurodegeneration, and the impact of stress and infection on mental health. Notable recent papers include:

  • COVID-19 infection outbreak increases anxiety level of general public in China: involved mechanisms and influencing factors (2020) - Journal of Affective Disorders
  • The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia (2022) - Translational Psychiatry
  • SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease (2023) - Aging and Disease
  • Deep rTMS Mitigates Behavioral and Neuropathologic Anomalies in Cuprizone-Exposed Mice Through Reducing Microglial Proinflammatory Cytokines (2020) - Frontiers in Integrative Neuroscience
  • Differential Susceptibility and Vulnerability of Brain Cells in C57BL/6 Mouse to Mitochondrial Dysfunction Induced by Short-Term Cuprizone Exposure (2020) - Frontiers in Neuroanatomy

Xu frequently publishes in the journals Translational Psychiatry, Frontiers in Integrative Neuroscience, BMC Psychiatry, bioRxiv (Cold Spring Harbor Laboratory), and the Journal of Affective Disorders.

Collaborative work is a significant aspect of Xu's research activities. Frequent coauthors include Qingjun Huang, Handi Zhang, Zeman Fang, Haiyan Zeng, and Zhuozhi Dai, reflecting a network of partnerships supporting interdisciplinary studies.

Best Publications

  • Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus

    Haiyun Xu;J Steven Richardson;Xin-Min Li

  • Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes.

    L Xiao;H Xu;Y Zhang;Z Wei

  • Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus.

    Haiyun Xu;Hong Qing;Wenfu Lu;David Keegan

  • Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress‐induced decrease in cell proliferation and BDNF expression in rat hippocampus

    Haiyun Xu;Zhong Chen;Zhong Chen;Jue He;Samson Haimanot

  • The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+-induced apoptosis.

    Hong Qing;Haiyun Xu;Zelan Wei;Kurt Gibson

  • Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.

    Haiyun Xu;Hong-Ju Yang;Yanbo Zhang;Richard Clough

  • Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination

    Yanbo Zhang;Handi Zhang;Lingyan Wang;Wengao Jiang

  • Current-induced magnetic resonance phase imaging.

    J. Bodurka;A. Jesmanowicz;J.S. Hyde;H. Xu

  • Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress.

    Can Luo;Haiyun Xu;Xin-Min Li

  • Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse

    Yanbo Zhang;Haiyun Xu;Wengao Jiang;Lan Xiao

  • Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics.

    Haiyun Xu;Hong-Ju Yang;Bryan McConomy;Ronald Browning

  • Olanzapine and quetiapine protect PC12 cells from β-amyloid peptide25–35-induced oxidative stress and the ensuing apoptosis

    Haitao Wang;Haiyun Xu;Lillian E Dyck;Xin-Min Li

  • Regulation of Astrocyte Pathology by Fluoxetine Prevents the Deterioration of Alzheimer Phenotypes in an APP/PS1 Mouse Model

    Jinping Qiao;Junhui Wang;Hongxing Wang;Yanbo Zhang

  • Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus

    Yuan Shao;Gen Yan;Yinghua Xuan;Hui Peng

  • The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia

    Unknown

  • Recovery of hippocampal cell proliferation and BDNF levels, both of which are reduced by repeated restraint stress, is accelerated by chronic venlafaxine

    H Xu;C Luo;J S Richardson;X M Li

  • Region-specific susceptibilities to cuprizone-induced lesions in the mouse forebrain: Implications for the pathophysiology of schizophrenia.

    Hong-Ju Yang;Haitao Wang;Yanbo Zhang;Lan Xiao

  • The response of synaptophysin and microtubule-associated protein 1 to restraint stress in rat hippocampus and its modulation by venlafaxine.

    Haiyun Xu;Jue He;J. Steven Richardson;Xin-Min Li

  • Neurochemical organization of the macaque retina: effect of TTX on levels and gene expression of cytochrome oxidase and nitric oxide synthase and on the immunoreactivity of Na+ K+ ATPase and NMDA receptor subunit I.

    Margaret T.T Wong-Riley;Zifang Huang;Wendy Liebl;Feng Nie

  • Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: effect of chronic administration of olanzapine.

    Can Luo;Haiyun Xu;Xin-Min Li

  • Heroin-induced neuronal activation in rat brain assessed by functional MRI.

    Haiyun Xu;Shi-jiang Li;Jerzy Bodurka;Xiaoli Zhao

Frequent Co-Authors

Xin-Min Li
Xin-Min Li University of Alberta
Ronald A. Browning
Ronald A. Browning Southern Illinois University Carbondale
Shi-Jiang Li
Shi-Jiang Li Medical College of Wisconsin
Zhijun Zhang
Zhijun Zhang Southeast University
Elliot A. Stein
Elliot A. Stein National Institute on Drug Abuse

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Related Online Degrees & Career Pathways

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