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Genji Imokawa

Genji Imokawa

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
17104
World Ranking
6691
National Ranking
443

Overview

Genji Imokawa is a researcher affiliated with Chubu University in Japan, specializing in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on dermatology and related subfields, including cell biology, molecular biology, pharmaceutical science, and pharmacology.

The scientist's work covers key topics such as dermatology and skin diseases, sphingolipid metabolism and signaling, skin protection and aging, advancements in transdermal drug delivery, proteoglycans and glycosaminoglycans research, melanin and skin pigmentation, and the pharmacological effects of natural compounds.

Selected recent publications by Genji Imokawa include:

  • Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role, 2021, International Journal of Molecular Sciences
  • Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype, 2020, Journal of Investigative Dermatology

Frequent co-authors in their research include Mariko Takada (6 collaborations), Shuko Terazawa (3 collaborations), Masahiko Nakano (3 collaborations), Akio Yamamoto (3 collaborations), and Kayoko Numano (2 collaborations).

Genji Imokawa frequently publishes in several scientific venues such as:

  • International Journal of Molecular Sciences (6 publications)
  • Journal of Investigative Dermatology (1 publication)
  • Journal of Biological Chemistry (1 publication)
  • PLoS ONE (1 publication)
  • Biomedicines (1 publication)

In addition to journal articles, the scientist has contributed to book publications with Book Publisher International (a part of SCIENCEDOMAIN International), including titles such as:

  • Cutting Edge on Molecular Mechanisms of Skin Ageing and Its Rational Anti-Aging Treatments and Pathogenesis of Atopic Dermatitis, 2021
  • Hyaluronan in the Skin: Mechanisms of Age-Dependent and UVA-Provoked Down-Regulated Secretion of Hyaluronan by Human Dermal Fibroblasts and Prospective Agents to Ameliorate the Hyaluronan Deficiency in Chronologically Aged Skin and Photo-aged Skin, 2021

Best Publications

  • Decreased level of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry skin ?

    Genji Imokawa;Akihito Abe;Kumi Jin;Yuko Higaki

  • Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis.

    T. Kobayashi;K. Urabe;A. Winder;C. Jiménez-Cervantes

  • Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes

    G Imokawa;Y Yada;M Miyagishi

  • Age-related changes in the elastic properties and thickness of human facial skin

    Y. Takema;Y. Yorimoto;M. Kawai;G. Imokawa

  • Effects of endothelins on signal transduction and proliferation in human melanocytes.

    Y. Yada;K. Higuchi;G. Imokawa

  • Decreased Levels of Sphingosine, a Natural Antimicrobial Agent, may be Associated with Vulnerability of the Stratum Corneum from Patients with Atopic Dermatitis to Colonization by Staphylococcus aureus

    Junko Arikawa;Mutsumi Ishibashi;Makoto Kawashima;Yutaka Takagi

  • Endothelin-1 as a New Melanogen: Coordinated Expression of Its Gene and the Tyrosinase Gene in UVB-Exposed Human Epidermis

    Genji Imokawa;Makoto Miyagishi;Yukihiro Yada

  • Importance of intercellular lipids in water-retention properties of the stratum corneum: induction and recovery study of surfactant dry skin.

    G Imokawa;S Akasaki;Y Minematsu;M Kawai

  • High-Expression of Sphingomyelin Deacylase is an Important Determinant of Ceramide Deficiency Leading to Barrier Disruption in Atopic Dermatitis1

    Junko Hara;Kazuhiko Higuchi;Reiko Okamoto;Makoto Kawashima

  • Selective recovery of deranged water-holding properties by stratum corneum lipids

    Genji Imokawa;Shuichi Akasaki;Michihiro Hattori;Naonobu Yoshizuka

  • Stratum corneum lipids serve as a bound-water modulator

    Genji Imokawa;Hiroshi Kuno;Michio Kawai

  • Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency?

    Yasuko Murata;Junko Ogata;Yuko Higaki;Makoto Kawashima

  • Tyrosinase Stabilization by Tyrp1 (the brown Locus Protein)

    Takeshi Kobayashi;Genji Imokawa;Dorothy C. Bennett;Vincent J. Hearing

  • The Paracrine Role of Stem Cell Factor/c-kit Signaling in the Activation of Human Melanocytes in Ultraviolet-B-Induced Pigmentation

    Akira Hachiya;Akemi Kobayashi;Atsushi Ohuchi;Yoshinori Takema

  • The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity.

    Naoko Tsuji;Shigeru Moriwaki;Yasuto Suzuki;Yoshinori Takema

  • Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis

    T. Kobayashi;W.D. Vieira;B. Potterf;C. Sakai

  • A possible function of structural lipids in the water-holding properties of the stratum corneum.

    Genji Imokawa;Michihiro Hattori

  • The Role of Endothelin-1 in Epidermal Hyperpigmentation and Signaling Mechanisms of Mitogenesis and Melanogenesis

    G Imokawa;T Kobayashi;M Miyagishi;K Higashi

  • Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide beta-1,4-galactosyltransferase From Rat Brain

    Tomoko Nomura;Minoru Takizawa;Junken Aoki;Hiroyuki Arai

  • Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes.

    Genji Imokawa;Yukihiro Yada;Mitsutoshi Kimura

Frequent Co-Authors

Makoto Miyagishi
Makoto Miyagishi National Institute of Advanced Industrial Science and Technology
Vincent J. Hearing
Vincent J. Hearing National Institutes of Health
Masahiro Takigawa
Masahiro Takigawa Hamamatsu University
Satoshi Omura
Satoshi Omura Kitasato University
Peter M. Elias
Peter M. Elias University of California, San Francisco
Kazumasa Wakamatsu
Kazumasa Wakamatsu Fujita Health University
Walter M. Holleran
Walter M. Holleran University of California, San Francisco
Howard I. Maibach
Howard I. Maibach University of California, San Francisco
David E. Fisher
David E. Fisher Harvard University
Masamitsu Ichihashi
Masamitsu Ichihashi Kobe University

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