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David W. Hoskin

David W. Hoskin

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11586
World Ranking
15544
National Ranking
544

Overview

David W. Hoskin is a researcher affiliated with Dalhousie University in Canada. Their work spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, with particular focus on molecular biology and pharmacology as key subfields. Their research interests include phytochemicals and antioxidant activities, genomics related to phytochemicals and oxidative stress, antimicrobial peptides, Piperaceae chemical and biological studies, cancer metabolism, natural product bioactivities and synthesis, and plant gene expression analysis.

Hoskin's recent papers reflect these research topics, covering studies published primarily in molecular biology and biomedical journals. Notable publications include:

  • Chemopreventive Effect of Dietary Anthocyanins against Gastrointestinal Cancers: A Review of Recent Advances and Perspectives, 2020, International Journal of Molecular Sciences
  • Instrumental role for reactive oxygen species in the inflammatory response, 2020, Frontiers in bioscience
  • Anthocyanin-rich haskap (Lonicera caerulea L.) berry extracts reduce nitrosamine-induced DNA damage in human normal lung epithelial cells, 2020, Food and Chemical Toxicology
  • Myeloid-derived suppressor cell depletion therapy targets IL-17A-expressing mammary carcinomas, 2020, Scientific Reports
  • Delivery of Apoptosis-inducing Piperine to Triple-negative Breast Cancer Cells via Co-polymeric Nanoparticles, 2020, Anticancer Research

Frequent co-authors collaborating with Hoskin include:

  • H.P. Vasantha Rupasinghe
  • Wasundara Fernando
  • Melanie R. Power Coombs
  • Madumani Amararathna
  • Javad Ghassemi Rad

Hoskin's publications appear in a variety of scientific venues, with multiple works published in:

  • International Journal of Molecular Sciences
  • Scientific Reports
  • Anticancer Research
  • Biomolecules
  • Frontiers in bioscience

Their contributions fall predominantly under the fields of biochemistry, genetics and molecular biology, with 22 publications, and medicine, represented in 18 publications. Within subfields, molecular biology accounts for 19 publications, pharmacology for 9, and biochemistry for 7, complemented by works in immunology and microbiology.

Best Publications

  • Studies on anticancer activities of antimicrobial peptides.

    David W. Hoskin;Ayyalusamy Ramamoorthy

  • The Extracellular Fluid of Solid Carcinomas Contains Immunosuppressive Concentrations of Adenosine

    Jonathan Blay;Thomas D. White;David W. Hoskin

  • Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment

    Jamie S Mader;David W Hoskin

  • Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.

    Jamie S. Mader;Jayme Salsman;David M. Conrad;David W. Hoskin

  • Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)

    David W Hoskin;Jamie S Mader;Suzanne J Furlong;David M Conrad

  • Thy-1: More than a Mouse Pan-T Cell Marker

    S. M. Mansour Haeryfar;David W. Hoskin

  • Piperine inhibits the growth and motility of triple-negative breast cancer cells

    Anna L. Greenshields;Carolyn D. Doucette;Kimberly M. Sutton;Laurence Madera

  • Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress

    Paul B. Yaffe;Melanie R. Power Coombs;Carolyn D. Doucette;Mark Walsh

  • Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells

    Jane L. Watson;Richard Hill;Paul B. Yaffe;Anna Greenshields

  • Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.

    Jane L. Watson;Anna Greenshields;Richard Hill;Ashley Hilchie

  • Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts

    Ashley L Hilchie;Carolyn D Doucette;Devanand M Pinto;Devanand M Pinto;Aleksander Patrzykat

  • Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate.

    Anna L. Greenshields;Trevor G. Shepherd;David W. Hoskin

  • Piperine, a dietary phytochemical, inhibits angiogenesis.

    Carolyn D. Doucette;Ashley L. Hilchie;Robert Liwski;David W. Hoskin

  • Bovine Lactoferricin Causes Apoptosis in Jurkat T-leukemia Cells by Sequential Permeabilization of the Cell Membrane and Targeting of Mitochondria

    Jamie S. Mader;Angela Richardson;Jayme Salsman;Deniz Top

  • Cutting Edge: Dendritic Cell Actin Cytoskeletal Polarization during Immunological Synapse Formation Is Highly Antigen-Dependent

    Monther M. Al-Alwan;Robert S. Liwski;S. M. Mansour Haeryfar;William H. Baldridge

  • Adenosine Acts through A2 Receptors to Inhibit IL-2-Induced Tyrosine Phosphorylation of STAT5 in T Lymphocytes: Role of Cyclic Adenosine 3′,5′-Monophosphate and Phosphatases

    Hong Zhang;David M. Conrad;Jared J. Butler;Chuanli Zhao

  • Eradication of established HPV 16-expressing tumors by a single administration of a vaccine composed of a liposome-encapsulated CTL-T helper fusion peptide in a water-in-oil emulsion.

    Pirouz Daftarian;Marc Mansour;Anita C. Benoit;Bill Pohajdak

  • Adenosine Inhibits the Adhesion of Anti-CD3-activated Killer Lymphocytes to Adenocarcinoma Cells through an A3 Receptor

    Willena M. MacKenzie;David W. Hoskin;Jonathan Blay

  • Piperine impairs cell cycle progression and causes reactive oxygen species-dependent apoptosis in rectal cancer cells

    Paul B. Yaffe;Carolyn D. Doucette;Mark Walsh;David W. Hoskin

  • Curcumin-Induced Apoptosis in PC3 Prostate Carcinoma Cells Is Caspase-Independent and Involves Cellular Ceramide Accumulation and Damage to Mitochondria

    Ashley L. Hilchie;Suzanne J. Furlong;Kimberly Sutton;Angela Richardson

Frequent Co-Authors

H.P. Vasantha Rupasinghe
H.P. Vasantha Rupasinghe Dalhousie University
Jean S. Marshall
Jean S. Marshall Dalhousie University
Susan E. Douglas
Susan E. Douglas Lloyds Banking Group (United Kingdom)
John C. Roder
John C. Roder University of Toronto
Robert E. W. Hancock
Robert E. W. Hancock University of British Columbia
Thomas J. Marrie
Thomas J. Marrie Dalhousie University
Neale D. Ridgway
Neale D. Ridgway Dalhousie University
Stephen K. Anderson
Stephen K. Anderson National Institutes of Health
Robert Anderson
Robert Anderson Dalhousie University
Hee-Jeong Im
Hee-Jeong Im University of Illinois at Chicago

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