David A. Knecht

Overview

Best Publications

• Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum

  David A. Knecht;William F. Loomis

  812
  Citations

• Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain.

  Deborah Wessels;David R. Soll;David Knecht;William F. Loomis

  400
  Citations

• Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

  Cameron C. Scott;Wendy Dobson;Roberto J. Botelho;Natasha Coady-Osberg

  296
  Citations

• Rho-Kinase and Myosin-II Control Phagocytic Cup Formation during CR, but Not FcγR, Phagocytosis

  Isabel M. Olazabal;Emmanuelle Caron;Robin C. May;Kerstin Schilling

  287
  Citations

• Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors.

  D A Knecht;S M Cohen;W F Loomis;H F Lodish

  271
  Citations

• Visualization of antigenic proteins on Western blots.

  David A. Knecht;Randall L. Dimond

  234
  Citations

• Silica-Induced Apoptosis in Mouse Alveolar Macrophages Is Initiated by Lysosomal Enzyme Activity

  Michael S. Thibodeau;Charles Giardina;David A. Knecht;Joseph Helble

  180
  Citations

• Targeted disruption of the ABP-120 gene leads to cells with altered motility.

  D Cox;J Condeelis;D Wessels;D Soll

  171
  Citations

• Variables Controlling the Expression Level of Exogenous Genes in Dictyostelium

  Ka Ming Pang;Michael A. Lynes;David A. Knecht

  170
  Citations

• Use of a fusion protein between GFP and an actin-binding domain to visualize transient filamentous-actin structures

  Ka Ming Pang;Eunkyung Lee;David A. Knecht

  154
  Citations

• Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments.

  Gary Laevsky;David A. Knecht

  138
  Citations

• Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.

  Andrew J. Muinonen-Martin;Olivia Susanto;Qifeng Zhang;Elizabeth Smethurst

  134
  Citations

• The Phagocytosis and Toxicity of Amorphous Silica

  Lindsey M. Costantini;Renée M. Gilberti;David A. Knecht

  133
  Citations

• Self-generated chemoattractant gradients: Attractant depletion extends the range and robustness of chemotaxis

  Luke Tweedy;David A. Knecht;Gillian M. Mackay;Robert H. Insall

  126
  Citations

• Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement.

  Maria L. Lombardi;David A. Knecht;Micah Dembo;Juliet Lee

  124
  Citations

• Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages

  Gaurav N. Joshi;David A. Knecht

  123
  Citations

• Metallothionein mediates leukocyte chemotaxis.

  Xiuyun Yin;David A Knecht;Michael A Lynes

  120
  Citations

• Actin filaments are severed by both native and recombinant dictyostelium cofilin but to different extents.

  Ilia Ichetovkin;Jinghua Han;K.M. Pang;David A. Knecht

  116
  Citations

• Antigenic determinants shared by lysosomal proteins of Dictyostelium discoideum. Characterization using monoclonal antibodies and isolation of mutations affecting the determinant.

  D A Knecht;R L Dimond;S Wheeler;W F Loomis

  115
  Citations

• Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum.

  David A. Knecht;Danny L. Fuller;William F. Loomis

  115
  Citations