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Biology and Biochemistry

D-Index
80
Citations
20078
World Ranking
4147
National Ranking
2033

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David A. Bernlohr is affiliated with the University of Minnesota in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans a broad range of subfields, including molecular biology, physiology, immunology, epidemiology, and cancer research.

Bernlohr's work primarily focuses on topics such as adipose tissue and metabolism, peroxisome proliferator-activated receptors, adipokines, inflammation, and metabolic diseases. They also investigate immune cell function and interaction, protein structure and dynamics, cancer, lipids, and metabolism, as well as advanced methodologies like single-cell and spatial transcriptomics.

Their frequent coauthors include Ann V. Hertzel, Cristina Olivieri, Caitlin Walker, Susan S. Taylor, and Gianluigi Veglia, each contributing significantly to multiple collaborative publications.

Bernlohr has published research in various venues, with multiple papers appearing in bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Communications Biology, Endocrinology, and the Journal of Lipid Research.

Selected recent papers highlight the scope of Bernlohr's research:

  • SenNet recommendations for detecting senescent cells in different tissues, 2024, Nature Reviews Molecular Cell Biology
  • Identification of gut microbiota and microbial metabolites regulated by an antimicrobial peptide lipocalin 2 in high fat diet-induced obesity, 2020, International Journal of Obesity
  • Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity, 2021, Cell Reports
  • ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy, 2022, Science Advances
  • Inflammatory Macrophage Interleukin-1β Mediates High-Fat Diet-Induced Heart Failure With Preserved Ejection Fraction, 2022, JACC Basic to Translational Science

Bernlohr was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2017.

Best Publications

  • Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins

    Leonard Banaszak;Nathan Winter;Zhaohui Xu;David A. Bernlohr

  • Oxidative Stress and Covalent Modification of Protein with Bioactive Aldehydes

    Paul A. Grimsrud;Hongwei Xie;Timothy J. Griffin;David A. Bernlohr

  • Metabolic functions of FABPs--mechanisms and therapeutic implications.

    Gökhan S. Hotamisligil;David A. Bernlohr

  • The Mammalian Fatty Acid-binding Protein Multigene Family: Molecular and Genetic Insights into Function

    Ann Vogel Hertzel;David A Bernlohr

  • Physiological properties and functions of intracellular fatty acid-binding proteins.

    Natalie Ribarik Coe;David A. Bernlohr

  • Identification of a Functional Peroxisome Proliferator-responsive Element in the Murine Fatty Acid Transport Protein Gene

    Brigitte I. Frohnert;To Y. Hui;David A. Bernlohr

  • Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels.

    Natalie Ribarik Coe;Melanie A. Simpson;David A. Bernlohr

  • The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages

    Jinhui Zhang;YingJie Wu;Yuanyuan Zhang;Derek LeRoith

  • European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

    Javier Egea;Isabel Fabregat;Yves M Frapart;Pietro Ghezzi

  • Oxidative stress and lipotoxicity

    Amy K. Hauck;David A. Bernlohr

  • Carbonylation of Adipose Proteins in Obesity and Insulin Resistance Identification of Adipocyte Fatty Acid-binding Protein as a Cellular Target of 4-Hydroxynonenal

    Paul A. Grimsrud;Matthew J. Picklo;Timothy J. Griffin;David A. Bernlohr

  • INTRACELLULAR LIPID-BINDING PROTEINS AND THEIR GENES

    David A. Bernlohr;Melanie A. Simpson;Ann Vogel Hertzel;Leonard J. Banaszak

  • The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase.

    Natalie Ribarik Coe;Anne Johnston Smith;Brigitte I. Frohnert;Paul A. Watkins

  • Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.

    Jessica M. Curtis;Paul A. Grimsrud;Wendy S. Wright;Xin Xu

  • Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway

    Valentina Parra;Valentina Parra;Hugo E. Verdejo;Hugo E. Verdejo;Myriam Iglewski;Andrea Del Campo

  • Characterization of the Acyl-CoA Synthetase Activity of Purified Murine Fatty Acid Transport Protein 1 *

    Angela M. Hall;Anne J. Smith;David A. Bernlohr

  • Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice.

    Hong Guo;Daozhong Jin;Yuanyuan Zhang;Wendy Wright

  • The adipocyte lipid-binding protein at 1.6-A resolution. Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids.

    Zhaohui Xu;David A. Bernlohr;Leonard J. Banaszak

  • Intracellular fatty acid trafficking and the role of cytosolic lipid binding proteins.

    Valerie Matarese;Randy L. Stone;David W. Waggoner;David A. Bernlohr

  • Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice.

    Angela M. Hall;Brian M. Wiczer;Thomas Herrmann;Wolfgang Stremmel

Frequent Co-Authors

Leonard J. Banaszak
Leonard J. Banaszak University of Minnesota
Sergio Lavandero
Sergio Lavandero University of Chile
Gianluigi Veglia
Gianluigi Veglia University of Minnesota
Edgar A. Arriaga
Edgar A. Arriaga University of Minnesota
Judith Storch
Judith Storch Rutgers, The State University of New Jersey
David D. Thomas
David D. Thomas University of Minnesota
George Barany
George Barany University of Minnesota
Michael J. Sadowsky
Michael J. Sadowsky University of Minnesota
Susan S. Taylor
Susan S. Taylor University of California, San Diego

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