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Cristina Mecucci

Cristina Mecucci

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
20917
World Ranking
8499
National Ranking
228

Overview

Cristina Mecucci is affiliated with the University of Perugia in Italy. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to several specialized subfields including Hematology, Molecular Biology, Genetics, Public Health, Environmental and Occupational Health, and Immunology.

Their main topics of work focus on various aspects of leukemia and related hematologic malignancies. The key areas of study include:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia research
  • Chronic Lymphocytic Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • CAR-T cell therapy research
  • Protein Degradation and Inhibitors
  • DNA Repair Mechanisms

Frequently publishing in prominent journals, Cristina Mecucci has contributed numerous articles to the following venues:

  • Blood
  • Clinical Lymphoma Myeloma & Leukemia
  • Cancer Genetics
  • Annals of Hematology
  • HemaSphere

The recent papers by Mecucci include the following:

  • "Acute lymphoblastic leukaemia", 2024, Nature Reviews Disease Primers
  • "HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions", 2021, Leukemia
  • "T-Cell Acute Lymphoblastic Leukemia: Biomarkers and Their Clinical Usefulness", 2021, Genes
  • "Philadelphia-like acute lymphoblastic leukemia is associated with minimal residual disease persistence and poor outcome. First report of the minimal residual disease-oriented GIMEMA LAL1913", 2020, Haematologica
  • "Guiding the global evolution of cytogenetic testing for hematologic malignancies", 2022, Blood

Cristina Mecucci collaborates frequently with several researchers, including:

  • Roberta La Starza
  • Caterina Matteucci
  • Danika Di Giacomo
  • Giovanni Roti
  • Silvia Arniani

Best Publications

  • Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype

    Brunangelo Falini;Christina Mecucci;Enrico Tiacci;Myriam Alcalay

  • Nucleophosmin and cancer

    Silvia Grisendi;Cristina Mecucci;Brunangelo Falini;Pier Paolo Pandolfi

  • Full Haplotype-Mismatched Hematopoietic Stem-Cell Transplantation: A Phase II Study in Patients With Acute Leukemia at High Risk of Relapse

    Franco Aversa;Adelmo Terenzi;Antonio Tabilio;Franca Falzetti

  • Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

    Ramiro Garzon;Michela Garofalo;Maria Paola Martelli;Roger Briesewitz

  • Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.

    Myriam Alcalay;Enrico Tiacci;Roberta Bergomas;Barbara Bigerna

  • The 5q− anomaly

    Herman Van den Berghe;Kristina Vermaelen;Cristina Mecucci;Dario Barbieri

  • Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

    Brunangelo Falini;Niccolò Bolli;Jing Shan;Maria Paola Martelli

  • Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations

    Paolo Gorello;G. Cazzaniga;F. Alberti;M. G. Dell'Oro

  • Myelodysplastic syndromes: recent advances.

    Emilio P. Alessandrino;Sergio Amadori;Mario Cazzola;Franco Locatelli

  • Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors

    Patrizia Barozzi;Mario Luppi;Fabio Facchetti;Cristina Mecucci

  • A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol.

    Marco Mancini;Daniela Scappaticci;Giuseppe Cimino;Mauro Nanni

  • Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia

    Brunangelo Falini;Maria Paola Martelli;Niccolò Bolli;Rossella Bonasso

  • AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.

    Claudia Haferlach;Cristina Mecucci;Susanne Schnittger;Alexander Kohlmann

  • NUCLEOPHOSMIN MUTATIONS IN CHILDHOOD ACUTE MYELOGENOUS LEUKEMIA WITH NORMAL KARYOTYPE.

    Giovanni Cazzaniga;Maria Grazia Dell'Oro;Cristina Mecucci;Emanuela Giarin

  • NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15)

    Roberto Rosati;Roberta La Starza;Angelo Veronese;Ana Aventin

  • Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

    Enrico Tiacci;Erik Ladewig;Gianluca Schiavoni;Alex Penson

  • H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22)

    Juerg Schwaller;Juerg Schwaller;Juerg Schwaller;Ema Anastasiadou;Ema Anastasiadou;Ema Anastasiadou;Danielle Cain;Danielle Cain;Danielle Cain;Jeff Kutok;Jeff Kutok;Jeff Kutok

  • Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

    Carmen Vicente;Claire Schwab;Michaël Broux;Ellen Geerdens

  • Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol.

    Antonella Vitale;Anna Guarini;Cristina Ariola;Marco Mancini

  • Myeloid Cell Differentiation Arrest by Mir-125b-1 in Myelodysplasic Syndrome and Acute Myeloid Leukemia with the T(2;11)(p21;q23) Translocation

    Marina Bousquet;Cathy Quelen;Roberto Rosati;Véronique Mansat-De Mas

Frequent Co-Authors

Massimo F. Martelli
Massimo F. Martelli University of Perugia
Jan Delabie
Jan Delabie University Health Network
Oskar A. Haas
Oskar A. Haas Medical University of Vienna
Myriam Alcalay
Myriam Alcalay University of Milan
Sante Tura
Sante Tura University of Bologna
Franco Mandelli
Franco Mandelli Sapienza University of Rome

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