World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
10954
World Ranking
15599
National Ranking
1227

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Apoptosis

His primary areas of investigation include Cell biology, Epstein–Barr virus, Cancer research, Epstein–Barr virus latent membrane protein 1 and Signal transduction. Christopher W. Dawson has included themes like Cell culture, Transcription factor, Apoptosis and CD40 in his Cell biology study. His Epstein–Barr virus study integrates concerns from other disciplines, such as B cell, Viral replication and Gammaherpesvirinae.

His Cancer research research incorporates themes from Cyclin-dependent kinase 9, ASK1, Mitogen-activated protein kinase kinase, Carcinogenesis and P70-S6 Kinase 1. His work carried out in the field of Epstein–Barr virus latent membrane protein 1 brings together such families of science as Protein kinase B, Akt/PKB signaling pathway and Kinase. His Signal transduction research is multidisciplinary, relying on both Internal medicine, Cytokine, Real-time polymerase chain reaction and Transcription.

His most cited work include:

  • Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death (538 citations)
  • Epstein-Barr virus gene expression in nasopharyngeal carcinoma. (401 citations)
  • Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiation (324 citations)

What are the main themes of his work throughout his whole career to date?

Christopher W. Dawson mainly focuses on Epstein–Barr virus, Cancer research, Cell biology, Virus and Signal transduction. His research integrates issues of Cell culture, Lytic cycle and Gammaherpesvirinae in his study of Epstein–Barr virus. His Cancer research study combines topics in areas such as Carcinogenesis, Regulation of gene expression, Downregulation and upregulation and Protein kinase B.

His biological study spans a wide range of topics, including Apoptosis, Epithelial cell differentiation, Transfection and CD40. His Virus study combines topics from a wide range of disciplines, such as Epitope, Monoclonal antibody and B cell. His Signal transduction study deals with Immune system intersecting with Antigen presentation.

He most often published in these fields:

  • Epstein–Barr virus (43.21%)
  • Cancer research (39.51%)
  • Cell biology (32.10%)

What were the highlights of his more recent work (between 2015-2019)?

  • Cancer research (39.51%)
  • Internal medicine (7.41%)
  • Signal transduction (20.99%)

In recent papers he was focusing on the following fields of study:

Christopher W. Dawson spends much of his time researching Cancer research, Internal medicine, Signal transduction, Hedgehog signaling pathway and Carcinogenesis. His Cancer research research includes themes of Epstein–Barr virus, Gene knockdown and Ectopic expression. His Epstein–Barr virus study improves the overall literature in Virus.

Signal transduction is a subfield of Cell biology that Christopher W. Dawson studies. The study incorporates disciplines such as Angiogenesis and Pharmacology, Drug in addition to Hedgehog signaling pathway. His Carcinogenesis research includes elements of Cell growth, Bromodeoxyuridine, Keratinocyte, Blot and Molecular biology.

Between 2015 and 2019, his most popular works were:

  • Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial (50 citations)
  • Repurposing itraconazole for the treatment of cancer. (24 citations)
  • Adjacent Lichen Sclerosis predicts local recurrence and second field tumour in women with vulvar squamous cell carcinoma (24 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Apoptosis

His primary areas of investigation include MEDLINE, Nasopharyngeal neoplasm, Transforming growth factor beta, Cell biology and Cell adhesion. His research in MEDLINE intersects with topics in Disease cluster, Laparotomy, Randomized controlled trial and Emergency medicine. Randomized controlled trial is intertwined with Audit and Quality management in his study.

His Nasopharyngeal neoplasm investigation overlaps with other areas such as Signal transduction, Integrin, Receptor, Fibronectin and p38 mitogen-activated protein kinases.

Best Publications

  • Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

    Sheila Henderson;David Huen;Martin Rowe;Chris Dawson

  • Epstein-Barr virus gene expression in nasopharyngeal carcinoma.

    L. S. Young;C. W. Dawson;D. Clark;H. Rupani

  • Epstein-Barr virus latent membrane protein inhibits human epithelial cell differentiation

    Christopher W. Dawson;Alan B. Rickinson;Lawrence S. Young

  • Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production.

    Aristides G. Eliopoulos;Neil J. Gallagher;Sarah M.S. Blake;Christopher W. Dawson

  • The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).

    Christopher W. Dawson;Rebecca J. Port;Lawrence S. Young

  • Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling.

    Christopher W. Dawson;Giorgos Tramountanis;Aristides G. Eliopoulos;Lawrence S. Young

  • Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

    Robert Valentine;Robert Valentine;Christopher W Dawson;Chunfang Hu;Khilan M Shah

  • Epstein-Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-kappaB pathway involving TNF receptor-associated factors.

    Aristides G Eliopoulos;Maria Stack;Christopher W Dawson;Kenneth M Kaye

  • Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.

    Clark D Russell;Cameron J Fairfield;Thomas M Drake;Lance Turtle

  • Epstein-Barr virus and nasopharyngeal carcinoma.

    Lawrence S. Young;Christopher W. Dawson

  • Epstein-Barr virus infection and replication in a human epithelial cell system.

    Q. X. Li;L. S. Young;G. Niedobitek;C. W. Dawson

  • Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action.

    Chris Tselepis;Ian Perry;Chris Dawson;Rob Hardy

  • CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator.

    A G Eliopoulos;C W Dawson;G Mosialos;J E Floettmann

  • The significance of LMP1 expression in nasopharyngeal carcinoma.

    Sai Wah Tsao;Giorgos Tramoutanis;Christopher W Dawson;Angela K.F Lo

  • Identification of a human epithelial cell surface protein sharing an epitope with the C3d/Epstein-Barr virus receptor molecule of B lymphocytes.

    L. S. Young;C. W. Dawson;K. W. Brown;A. B. Rickinson

  • Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.

    Amanda Dutton;Gary M Reynolds;Christopher W Dawson;Lawrence S Young

  • CD40 and epithelial cells: across the great divide

    Lawrence S Young;Aristides G Eliopoulos;Neil J Gallagher;Chris W Dawson

  • Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial

    Carol J Peden;Tim Stephens;Graham Martin;Brennan C Kahan

  • Immunohistochemical Detection of the Epstein-Barr Virus–Encoded Latent Membrane Protein 2A in Hodgkin's Disease and Infectious Mononucleosis

    G. Niedobitek;E. Kremmer;H. Herbst;L. Whitehead

  • Epstein-Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFbeta signaling pathways.

    V H J Wood;J D O'Neil;W Wei;S E Stewart

Frequent Co-Authors

Lawrence S. Young
Lawrence S. Young University of Warwick
Aristides G. Eliopoulos
Aristides G. Eliopoulos National and Kapodistrian University of Athens
Kwok Wai Lo
Kwok Wai Lo Chinese University of Hong Kong
Alan B. Rickinson
Alan B. Rickinson University of Birmingham
Gerald Niedobitek
Gerald Niedobitek University of Erlangen-Nuremberg
Sai Wah Tsao
Sai Wah Tsao University of Hong Kong
Andrew I. Bell
Andrew I. Bell University of Birmingham
Michael J. O. Wakelam
Michael J. O. Wakelam Babraham Institute
Shannon C. Kenney
Shannon C. Kenney University of Wisconsin–Madison
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society

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