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Genetics

D-Index
67
Citations
23111
World Ranking
2501
National Ranking
317

Overview

C. Geoffrey Woods is affiliated with the University of Cambridge in the United Kingdom. Their research primarily intersects the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions also found in Medicine and Neuroscience. The scientist's work further spans across several specialized subfields, including Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Genetics, and Neurology.

The scientist's recent publications address various aspects of pain mechanisms, ion channel function, and hereditary neurological disorders. Notable papers include:

  • Understanding the genetic basis of congenital insensitivity to pain (2020, British Medical Bulletin)
  • Nav1.7 is required for normal C-low threshold mechanoreceptor function in humans and mice (2021, Brain)
  • Genetic pain loss disorders (2022, Nature Reviews Disease Primers)
  • Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel KV6.4 Subunit (2020, Cell Reports)
  • Genetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies (2023, Brain)

The frequent publication venues for Woods include Brain, Journal of Medical Genetics, bioRxiv (Cold Spring Harbor Laboratory), SSRN Electronic Journal, and British Medical Bulletin.

The main research topics covered in Woods's body of work are:

  • Pain Mechanisms and Treatments
  • Ion channel regulation and function
  • Hereditary Neurological Disorders
  • Genetics and Neurodevelopmental Disorders
  • Neurological diseases and metabolism
  • Genomics and Rare Diseases
  • Genomic variations and chromosomal abnormalities

Collaborations appear frequently with several co-authors, notably:

  • John N. Wood
  • James J. Cox
  • Ichrak Drissi
  • David Bennett
  • Andreas C. Themistocleous

Overall, the research contributions of C. Geoffrey Woods present a focused investigation into the genetic and molecular mechanisms underlying pain sensitivity and hereditary sensory disorders, with multiple interdisciplinary overlaps spanning neuroscience, genetics, and clinical medicine.

Best Publications

  • An SCN9A channelopathy causes congenital inability to experience pain

    James J Cox;Frank Reimann;Adeline K. Nicholas;Gemma K Thornton

  • Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.

    Alfredo Ramirez;André Heimbach;Jan Gründemann;Barbara Stiller

  • A splicing mutation affecting expression of ataxia–telangiectasia and Rad3–related protein (ATR) results in Seckel syndrome

    Mark O'Driscoll;Victor L Ruiz-Perez;C Geoffrey Woods;Penny A Jeggo

  • Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome.

    Jacopo Celli;Pascal Duijf;Ben C.J Hamel;Michael Bamshad

  • Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes

    Heather C Mefford;Andrew J Sharp;Carl Baker;Andy Itsara

  • Mutation Spectrum and Genotype-Phenotype Analyses in Cowden Disease and Bannayan-Zonana Syndrome, Two Hamartoma Syndromes With Germline PTEN Mutation

    Debbie J. Marsh;Valérie Coulon;Kathryn L. Lunetta;Philippe Rocca-Serra

  • Flies without Centrioles

    Renata Basto;Joyce Lau;Tatiana Vinogradova;Tatiana Vinogradova;Alejandra Gardiol

  • Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.

    Yanick J Crow;Yanick J Crow;Andrea Leitch;Bruce E Hayward;Anna Garner

  • ASPM is a major determinant of cerebral cortical size.

    Jacquelyn Bond;Emma Roberts;Ganesh H. Mochida;Ganesh H. Mochida;Daniel J. Hampshire

  • A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size.

    Jacquelyn Bond;Emma Roberts;Kelly Springell;Sophia Lizarraga

  • PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron

    Neil V Morgan;Shawn K Westaway;Jenny E V Morton;Allison Gregory

  • Identification of Microcephalin, a Protein Implicated in Determining the Size of the Human Brain

    Andrew P. Jackson;Andrew P. Jackson;Helen Eastwood;Sandra M. Bell;Jimi Adu

  • Autosomal Recessive Primary Microcephaly (MCPH): A Review of Clinical, Molecular, and Evolutionary Findings

    C. Geoffrey Woods;Jacquelyn Bond;Wolfgang Enard

  • A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome

    Barbara Kremeyer;Francisco Lopera;James J. Cox;James J. Cox;Aliakmal Momin

  • Primary microcephaly: do all roads lead to Rome?

    Gemma K. Thornton;C. Geoffrey Woods

  • Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome

    Vincent Cantagrel;Jennifer L. Silhavy;Stephanie L. Bielas;Dominika Swistun

  • Centrosomes and cilia in human disease.

    Mónica Bettencourt-Dias;Friedhelm Hildebrandt;David Pellman;Geoff Woods

  • INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse

    Monique Jacoby;James J Cox;Stéphanie Gayral;Daniel J Hampshire

  • Pain perception is altered by a nucleotide polymorphism in SCN9A

    Frank Reimann;James J. Cox;Inna Belfer;Luda Diatchenko

  • WDR62 is associated with the spindle pole and is mutated in human microcephaly

    Adeline K. Nicholas;Maryam Khurshid;Julie Désir;Ofélia P. Carvalho

Frequent Co-Authors

Enza Maria Valente
Enza Maria Valente University of Pavia
Eamonn R. Maher
Eamonn R. Maher University of Cambridge
John Wood
John Wood University College London
Andrew P. Jackson
Andrew P. Jackson University of Edinburgh
Yanick J. Crow
Yanick J. Crow Université Paris Cité
Colin A. Johnson
Colin A. Johnson University of Leeds
Enrico Bertini
Enrico Bertini Bambino Gesù Children's Hospital
Frank Reimann
Frank Reimann University of Cambridge
Joseph G. Gleeson
Joseph G. Gleeson University of California, San Diego
Christopher A. Walsh
Christopher A. Walsh Howard Hughes Medical Institute

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