Bernard P. Roques

Best Publications

• Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene.

  Hans W. D. Matthes;Rafael Maldonado;Frédéric Simonin;Olga Valverde

  2126
  Citations

• Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB1 Receptor Knockout Mice

  Catherine Ledent;Olga Valverde;Gregorio Cossu;François Petitet

  1536
  Citations

• Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

  Rafael Maldonado;Adolfo Saiardi;Olga Valverde;Tarek A. Samad

  600
  Citations

• International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors.

  Florence Noble;Stephen A. Wank;Jacqueline N. Crawley;Jacques Bradwejn

  503
  Citations

• Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB

  Rafael Maldonado;Julie A. Blendy;Eleni Tzavara;Peter Gass

  391
  Citations

• Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes.

  Marie-Claude Fournie-Zaluski;Pierre Chaillet;Romaine Bouboutou;Annie Coulaud

  250
  Citations

• Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.

  Bernard P. Roques;Marie-Claude Fournié-Zaluski;Michel Wurm

  247
  Citations

• CCK-B receptor: chemistry, molecular biology, biochemistry and pharmacology

  Florence Noble;Bernard P. Roques

  234
  Citations

• Δ9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect

  Olga Valverde;Florence Noble;Françoise Beslot;Valérie Daugé

  234
  Citations

• Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Δ-9-tetrahydrocannabinol

  Daniel M Hutcheson;Eleni Th. Tzavara;Claire Smadja;Emmanuel Valjent

  229
  Citations

• Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: A new highly potent and fully specific agonist for opiate δ-receptors

  Jean-Marie Zajac;Gilles Gacel;Françis Petit;Pierre Dodey

  227
  Citations

• Aminopeptidase A inhibitors as potential central antihypertensive agents.

  Annabelle Reaux;Marie Claude Fournie-Zaluski;Christelle David;Sylvie Zini

  226
  Citations

• "Mixed inhibitor-prodrug" as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes.

  Marie Claude Fournie-Zaluski;Pascal Coric;Serge Turcaud;Evelyne Lucas

  216
  Citations

• Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid delta and dopamine D1 receptor stimulation.

  Ana Baamonde;Valérie Daugé;Mariano Ruiz-Gayo;Ion Gigel Fulga

  184
  Citations

• A highly sensitive fluorometric assay for "enkephalinase," a neutral metalloendopeptidase that releases tyrosine-glycine-glycine from enkephalins.

  Dominique Florentin;Dominique Florentin;Amor Sassi;Amor Sassi;Bernárd P. Roques;Bernárd P. Roques

  178
  Citations

• Differential Inhibition of Aminopeptidase A and Aminopeptidase N by New .beta.-Amino Thiols

  Eric N. Chauvel;Catherine Llorens-Cortes;Pascale Coric;Sherwin Wilk

  175
  Citations

• Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.

  Julie Salzmann;Cynthia Marie-claire;Stéphanie Le Guen;Bernard P Roques

  174
  Citations

• Reduction of opioid dependence by the CB1 antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction

  Magdalena Mas-Nieto;Blandine Pommier;Eleni T Tzavara;Anne Caneparo

  162
  Citations

• Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors

  Olga Valverde;Catherine Ledent;Francoise Beslot;Marc Parmentier

  159
  Citations

• D‐Tyr—Ser—Gly—Phe—Leu—Thr, a highly preferential ligand for δ‐opiate receptors

  Unknown

  158
  Citations