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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
12764
World Ranking
9318
National Ranking
245

Overview

Alex Bobik is a researcher affiliated with the Baker IDI Heart and Diabetes Institute in Australia, whose work primarily spans the fields of Medicine and Immunology and Microbiology. Their research contributions include significant exploration into Immunology, Cardiology and Cardiovascular Medicine, Immunology and Allergy, Surgery, and Nutrition and Dietetics.

The scientist's research topics focus mainly on aspects of Atherosclerosis and Cardiovascular Diseases, Cell Adhesion Molecules Research, T-cell and B-cell Immunology, Coronary Interventions and Diagnostics, Cardiac Fibrosis and Remodeling, Viral Infections and Immunology Research, and Sodium Intake and Health.

Among their recent papers are:

  • B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis (2020, Frontiers in Immunology)
  • Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms (2020, European Heart Journal)
  • The tandem stenosis mouse model: Towards understanding, imaging, and preventing atherosclerotic plaque instability and rupture (2020, British Journal of Pharmacology)
  • An Ultrasound-Responsive Theranostic Cyclodextrin-Loaded Nanoparticle for Multimodal Imaging and Therapy for Atherosclerosis (2022, Small)
  • Association of constipation with increased risk of hypertension and cardiovascular events in elderly Australian patients (2023, Scientific Reports)

Bobik has collaborated frequently with several co-authors, notably Karlheinz Peter, Tin Kyaw, Peter Kanellakis, Grant R. Drummond, and Jonathan Noonan. These collaborations reflect a network of researchers who contribute to overlapping areas in cardiovascular and immunological sciences.

Their work has appeared repeatedly in prominent venues, including the European Heart Journal, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Small, and Expert Opinion on Therapeutic Targets.

Best Publications

  • Growth factor activity of endothelin on vascular smooth muscle.

    A. Bobik;A. Grooms;J. A. Millar;A. Mitchell

  • Determination of norepinephrine apparent release rate and clearance in humans.

    Murray Esler;Graham Jackman;Alex Bobik;Dianne Kelleher

  • B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions

    Tin Kyaw;Christopher Tay;Surendran Krishnamurthi;Peter Kanellakis

  • Increased Expression of the DNA-Binding Cytokine HMGB1 in Human Atherosclerotic Lesions: Role of Activated Macrophages and Cytokines

    N. Kalinina;A. Agrotis;Y. Antropova;G. DiVitto

  • Conventional B2 B Cell Depletion Ameliorates whereas Its Adoptive Transfer Aggravates Atherosclerosis

    Tin Kyaw;Christopher Tay;Abdul Khan;Vanessa Dumouchel

  • Transforming Growth Factor-βs and Vascular Disorders

    Alex Bobik

  • Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque

    James A. Shaw;Alex Bobik;Andrew Murphy;Peter Kanellakis

  • Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

    Steffen U. Eisenhardt;Jonathon Habersberger;Andrew Murphy;Yung-Chih Chen

  • Cytotoxic and Proinflammatory CD8+ T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice

    Tin Kyaw;Amy Winship;Christopher Tay;Peter Kanellakis

  • Blocking IL-6 trans-Signaling Prevents High-Fat Diet-Induced Adipose Tissue Macrophage Recruitment but Does Not Improve Insulin Resistance

    Michael J. Kraakman;Helene L. Kammoun;Tamara L Allen;Virginie Deswaerte

  • Nongenomic Effects of Aldosterone on Intracellular Ca2+ in Vascular Smooth Muscle Cells

    Martin Wehling;Craig B. Neylon;Meryl Fullerton;Alex Bobik

  • The peripheral kinetics of norepinephrine in depressive illness.

    Murray Esler;John Turbott;Rosemary Schwarz;Paul Leonard

  • Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function.

    Craig B. Neylon;Richard J. Lang;Ying Fu;Alex Bobik

  • Renin-angiotensin system in neonatal rats: Induction of a renal abnormality in response to ACE inhibition or angiotensin II antagonism

    Peter Friberg;Birgitta Sundelin;Sven-Olof Bohman;Alexander Bobik

  • Distinct Patterns of Transforming Growth Factor-β Isoform and Receptor Expression in Human Atherosclerotic Lesions Colocalization Implicates TGF-β in Fibrofatty Lesion Development

    Alex Bobik;Alex Agrotis;Peter Kanellakis;Rodney Dilley

  • Obligatory Role for B Cells in the Development of Angiotensin II–Dependent Hypertension

    Christopher Te-Lee Chan;Christopher G Sobey;Maggie Lieu;Dorota M Ferens

  • Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation.

    Tin Kyaw;Christopher Tay;Christopher Tay;Hamid Reza Hosseini;Hamid Reza Hosseini;Peter Kanellakis

  • Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries.

    Michael R. Ward;Peter Kanellakis;Debra Ramsey;John Funder

  • Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis

    Tam N Dinh;Tin Soe Kyaw;Peter Kanellakis;Kelly Yen-Yon To

  • A Novel Mouse Model of Atherosclerotic Plaque Instability for Drug Testing and Mechanistic/Therapeutic Discoveries Using Gene and microRNA Expression Profiling

    Yung-Chih Chen;Anh Viet Bui;Jeannine Diesch;Richard Manasseh

Frequent Co-Authors

Peter J. Little
Peter J. Little University of the Sunshine Coast
Garry L. Jennings
Garry L. Jennings University of Sydney
Peter G. Tipping
Peter G. Tipping Monash University
Karlheinz Peter
Karlheinz Peter Baker IDI Heart and Diabetes Institute
Vsevolod A. Tkachuk
Vsevolod A. Tkachuk Lomonosov Moscow State University
Ban-Hock Toh
Ban-Hock Toh Monash University
Anthony M. Dart
Anthony M. Dart Monash University
Murray D. Esler
Murray D. Esler Baker IDI Heart and Diabetes Institute
Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
Mark A. Febbraio
Mark A. Febbraio Monash University

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