Human Immunology

Top Research Topics at Human Immunology?

The objective of Human Immunology is to combine knowledge in the areas of Immunology, Human leukocyte antigen, Genetics, Allele and Molecular biology. Genotype and Transplantation are some topics wherein Immunology research discussed in Human Immunology have an impact. The research on Human leukocyte antigen featured in it combines topics in other fields like Virology, Internal medicine, Epitope, Computational biology and Major histocompatibility complex.

The journal addresses concerns in Internal medicine which are intertwined with other disciplines, such as Endocrinology and Oncology. It focuses on different Genetics studies like Haplotype, Gene, Typing, Allele frequency and Locus (genetics). Linkage disequilibrium is a focus of the presented Haplotype works and it dives deep in Linkage disequilibrium.

The works on Allele deal in particular with HLA-A. The studies in Molecular biology featured incorporate elements of Cytotoxic T cell and Monoclonal antibody. Human Immunology focuses on Antigen research which is adjacent to topics in T cell.

• Immunology (42.09%)
• Human leukocyte antigen (33.15%)
• Genetics (23.80%)

What are the most cited papers published in the journal?

• A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. (566 citations)
• Hla types in celiac disease patients not carrying the DQA105-DQB102 (DQ2) heterodimer: results from the european genetics cluster on celiac disease (484 citations)
• Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. (399 citations)

Research areas of the most cited articles at Human Immunology:

The published papers are mainly concerned with subjects like Immunology, Human leukocyte antigen, Genetics, Allele and Antigen. The most cited articles focus on Immunology but the discussions also offer insight into other areas such as Genotype, Transplantation and Virology. While work presented in the published papers provide substantial information on Human leukocyte antigen, it also covers topics in Epitope, Molecular biology and Major histocompatibility complex.

What topics the last edition of the journal is best known for?

• Internal medicine
• Gene
• Disease

The previous edition focused in particular on these issues:

The journal mainly tackles studies in Human leukocyte antigen, Immunology, Immune system, Allele and Transplantation. It focuses on Human leukocyte antigen research as part of the broader topic of Genetics. Research on Immunology addressed in the journal frequently intersections with the field of Disease.

The journal explores issues in Allele which can be linked to other research areas like Typing and Major histocompatibility complex. The research on Transplantation tackled can also make contributions to studies in the areas of Genotyping, Kidney and Histocompatibility. The tackled Genotype research is interrelated with Internal medicine which concerns subjects like Antibody.

The most cited articles from the last journal are:

• Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade. (12 citations)
• A long road/read to rapid high-resolution HLA typing: The nanopore perspective. (9 citations)
• pHLA3D: Updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules (7 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Human Immunology (based on the number of publications) are:

• Marcelo Fernandez-Vina (172 papers) published 2 papers at the last edition, 1 more than at the previous edition,
• Elaine F. Reed (155 papers) absent at the last edition,
• Peter Stastny (128 papers) absent at the last edition,
• Frans H.J. Claas (109 papers) absent at the last edition,
• T. Mohanakumar (108 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Human Immunology (based on the number of publications) are:

• Gulf Coast Regional Blood Center (197 papers) published 4 papers at the last edition, 1 more than at the previous edition,
• University of California, Los Angeles (195 papers) published 1 paper at the last edition the same number as at the previous edition,
• Stanford University (181 papers) published 2 papers at the last edition, 1 more than at the previous edition,
• Harvard University (179 papers) published 1 paper at the last edition, 30 less than at the previous edition,
• University of Pittsburgh (164 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 4.00% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 11.67% were posted by at least one author from the top 10 institutions publishing in the journal. Another 9.17% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 5.83% of all publications and 73.33% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.