Chemical Research in Toxicology

Top Research Topics at Chemical Research in Toxicology?

Chemical Research in Toxicology generally zeroes in on subjects such as Biochemistry, Stereochemistry, Adduct, DNA and Glutathione. Topics like Enzyme, Metabolite, Microsome, Carcinogen and Metabolism are tackled as part of the discussions on Biochemistry. Studies on Metabolite discussed in it link to the field of Pharmacology.

Chemical Research in Toxicology dives deep in exploring the relationship between the study of Microsome and Cytochrome P450. While work presented in the journal provided substantial information on Stereochemistry, it also covered topics in Pyrene, Electrophile, Cysteine and Epoxide. The Adduct works featured in it incorporate elements from Chromatography and Deoxyadenosine.

Discussions in the journal are anchored in the subject of Chromatography and the similar topic of Urine. It explores issues in DNA which can be linked to other research areas like Molecular biology and Guanine. Organic chemistry study tackled is connected to the field of Medicinal chemistry.

• Biochemistry (30.86%)
• Stereochemistry (24.93%)
• Adduct (16.96%)

What are the most cited papers published in the journal?

• Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. (2191 citations)
• Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. (1304 citations)
• Role of quinones in toxicology. (1284 citations)

Research areas of the most cited articles at Chemical Research in Toxicology:

Biochemistry, Stereochemistry, Glutathione, Adduct and DNA are the main subjects of interest in the journal papers. In the Biochemistry research discussed in the most cited papers, Enzyme, Carcinogen, Metabolite, Microsome and Metabolism are all tackled. The studies tackled in the journal papers, which mainly focus on Stereochemistry, apply to Electrophile as well.

What topics the last edition of the journal is best known for?

• Enzyme
• Gene
• Internal medicine

The previous edition focused in particular on these issues:

Pharmacology, Toxicity, Computational biology, Biochemistry and In vivo are the subjects of interest in the journal. Chemical Research in Toxicology explores research in Pharmacology and the adjacent study of Neurotoxicity. The journal investigates Computational biology research which frequently intersects with In silico.

The majority of Biochemistry studies presented zero in on DNA. Chromatography and In vitro are some topics wherein In vivo research discussed in the journal have an impact.

The most cited articles from the last journal are:

• The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology. (14 citations)
• GLORYx: Prediction of the Metabolites Resulting from Phase 1 and Phase 2 Biotransformations of Xenobiotics (14 citations)
• Exposure of Human Lung Cells to Polystyrene Microplastics Significantly Retards Cell Proliferation and Triggers Morphological Changes. (11 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Chemical Research in Toxicology (based on the number of publications) are:

• Stephen S. Hecht (121 papers) published 3 papers at the last edition, 1 less than at the previous edition,
• F. Peter Guengerich (94 papers) published 1 paper at the last edition, 1 less than at the previous edition,
• Lawrence J. Marnett (83 papers) absent at the last edition,
• Robert J. Turesky (61 papers) absent at the last edition,
• Judy L. Bolton (58 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Chemical Research in Toxicology (based on the number of publications) are:

• Vanderbilt University (300 papers) published 1 paper at the last edition, 3 less than at the previous edition,
• University of Minnesota (227 papers) published 6 papers at the last edition, 5 less than at the previous edition,
• National Institutes of Health (186 papers) published 10 papers at the last edition, 6 more than at the previous edition,
• University of North Carolina at Chapel Hill (108 papers) published 5 papers at the last edition, 2 less than at the previous edition,
• Massachusetts Institute of Technology (100 papers) absent at the last edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 9.65% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 11.65% were posted by at least one author from the top 10 institutions publishing in the journal. Another 9.22% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 16.02% of all publications and 63.11% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.