World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
85
Citations
23318
World Ranking
2709
National Ranking
935

Research.com Recognitions

  • 2018 - Ryoji Noyori Prize, Society of Synthetic Organic Chemistry
  • 2001 - Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier
  • 2001 - Ernest Guenther Award, American Chemical Society (ACS)
  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1985 - Fellow of the American Academy of Arts and Sciences
  • 1980 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Yoshito Kishi was affiliated with Harvard University in the United States. Their research spanned multiple fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader categories, Kishi's work concentrated on subfields such as Pharmacology, Organic Chemistry, Oncology, Biotechnology, and Cancer Research.

The main research topics covered by Kishi included:

  • Microbial Natural Products and Biosynthesis
  • Synthetic Organic Chemistry Methods
  • Marine Sponges and Natural Products
  • Cancer Treatment and Pharmacology
  • Traditional and Medicinal Uses of Annonaceae
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Cancer, Hypoxia, and Metabolism

Notable recent papers published by Kishi or their collaborators were:

  • Total Synthesis of Halistatins 1 and 2, 2020, published in Journal of the American Chemical Society
  • Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials, 2024, Organic Letters
  • What Does It Take to Develop Structurally Complex Molecules by Total Synthesis? Rapid Process Development and GMP Manufacturing of E7130 Drug Substance for First-in-Human Clinical Study, 2024, Organic Process Research & Development
  • Abstract 4179: E7130 derived from total synthesis of halichondrin as a novel tumor-microenvironment ameliorator, 2020, Cancer Research
  • Abstract 4183: Mechanism of action analysis of anti-CAF activity of E7130, a novel tumor-microenvironment ameliorator, 2020, Cancer Research

Frequent coauthors who worked alongside Kishi included:

  • Osamu Asano
  • Yosuke Kaburagi
  • Kazunobu Kira
  • Kenzo Yahata
  • Kentaro Iso

Kishi's work was often published in venues such as:

  • Cancer Research
  • Organic Letters
  • Journal of the American Chemical Society
  • Organic Process Research & Development
  • European Journal of Cancer

During their career, Kishi received several awards including:

  • Ryoji Noyori Prize, Society of Synthetic Organic Chemistry, 2018
  • Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier, 2001
  • Ernest Guenther Award, American Chemical Society (ACS), 2001
  • Fellow of the American Association for the Advancement of Science (AAAS), 1999
  • Fellow of the American Academy of Arts and Sciences, 1985
  • Fellow of John Simon Guggenheim Memorial Foundation, 1980

Best Publications

  • Highly stereoselective approaches to .alpha.- and .beta.-C-glycopyranosides

    Michael D. Lewis;Jin Kun Cha;Yoshito Kishi

  • Catalytic effect of nickel(II) chloride and palladium(II) acetate on chromium(II)-mediated coupling reaction of iodo olefins with aldehydes

    Haolun. Jin;Junichi. Uenishi;William J. Christ;Yoshito. Kishi

  • In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B

    Murray J. Towle;Kathleen A. Salvato;Jacqueline Budrow;Bruce F. Wels

  • On stereochemistry of osmium tetraoxide oxidation of allylic alcohol systems. Empirical rule

    J.K. Cha;W.J. Christ;Y. Kishi

  • Total synthesis of halichondrin B and norhalichondrin B

    Thomas D. Aicher;Keith R. Buszek;Francis G. Fang;Craig J. Forsyth

  • Further synthetic studies on rifamycin s

    Hiroto Nagaoka;Yoshito Kishi

  • Dramatic rate enhancement of Suzuki diene synthesis. Its application to palytoxin synthesis

    Junichi Uenishi;Jean Marie Beau;Robert W. Armstrong;Yoshito Kishi

  • Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

    Galina Kuznetsov;Murray J. Towle;Hongsheng Cheng;Takanori Kawamura

  • Semi-synthetic aequorins with improved sensitivity to Ca2+ ions

    O Shimomura;B Musicki;Y Kishi

  • Stereocontrolled synthesis of D-pentitols, 2-amino-2-deoxy-D-pentitols and 2-deoxy-D-pentitols from D-glyceraldehyde acetonide

    Norio Minami;Soo Sung Ko;Yoshito Kishi

  • Semi-synthetic aequorin. An improved tool for the measurement of calcium ion concentration.

    O Shimomura;O Shimomura;B Musicki;Y Kishi

  • Reductive ring openings of allyl-alcohol epoxides

    James M. Finan;Yoshito Kishi

  • A total synthesis of lasalocid A

    T. Nakata;G. Schmid;B. Vranesic;M. Okigawa

  • An improved procedure for the Blaise reaction: a short, practical route to the key intermediates of the saxitoxin synthesis

    Steven M. Hannick;Yoshito Kishi

  • Synthesis of mono and unsymmetrical bis ortho esters of scyllo-inositol

    Hyo Won Lee;Yoshito Kishi

  • Total Synthesis of Pinnatoxin A

    John A. McCauley;Kazuo Nagasawa;Peter A. Lander;Steven G. Mischke

  • Synthetic studies on polyether antibiotics. 5. Total synthesis of monensin. 2. Stereocontrolled synthesis of the right half of monensin

    G. Schmid;T. Fukuyama;K. Akasaka;Y. Kishi

  • Complete Relative Stereochemistry of Maitotoxin

    Wanjun Zheng;John A. DeMattei;Jiang-Ping Wu;James J.-W. Duan

  • Synthetic studies on tetrodotoxin and related compounds. IV. Stereospecific total syntheses of DL-tetrodotoxin

    Y. Kishi;T. Fukuyama;M. Aratani;F. Nakatsubo

  • A stereospecific total synthesis of d,l-saxitoxin.

    H Tanino;T Nakata;T Kaneko;Y Kishi

  • Light-emitting properties of recombinant semisynthetic aequorins and recombinant fluorescein-conjugated aequorin for measuring cellular calcium

    O. Shimomura;O. Shimomura;B. Musicki;Y. Kishi;S. Inouye

Frequent Co-Authors

Toshio Goto
Toshio Goto Nagoya University
Osamu Shimomura
Osamu Shimomura Marine Biological Laboratory
Daisuke Uemura
Daisuke Uemura Kanagawa University
Yoshimasa Hirata
Yoshimasa Hirata Meijo University
Tohru Fukuyama
Tohru Fukuyama Nagoya University
Hideshi Nakamura
Hideshi Nakamura Nagoya University
Michael Rowley
Michael Rowley Pharmaron (United Kingdom)
Dolores Pérez-Sala
Dolores Pérez-Sala Spanish National Research Council
Eric L. Nuermberger
Eric L. Nuermberger Johns Hopkins University
Ki-Hyun Kim
Ki-Hyun Kim Hanyang University

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