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Chemistry

D-Index
74
Citations
21586
World Ranking
4628
National Ranking
1461

Overview

Osamu Shimomura was primarily affiliated with the Marine Biological Laboratory in the United States. Their research was situated mostly within the field of Medicine, producing 113 publications. Within this broad area, the focus extended into several subfields with notable activity in Surgery, Oncology, Pulmonary and Respiratory Medicine, Molecular Biology, and Immunology.

The scientist's research topics included:

  • Glycosylation and Glycoproteins Research
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Galectins and Cancer Biology
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Research and Treatments
  • Cancer Cells and Metastasis

Throughout their career, Osamu Shimomura frequently published in the following venues:

  • Surgical Case Reports
  • Cancer Research
  • BMC Surgery
  • Cancer Science
  • International Journal of Clinical Oncology

Their collaborative network included frequent coauthors such as Tatsuya Oda (48 publications), Yoshihiro Miyazaki (35 publications), Shinji Hashimoto (33 publications), Yoshimasa Akashi (32 publications), and Tsuyoshi Enomoto (31 publications).

Among recent papers authored in collaboration, notable works included:

  • Characterization of the Human Intestinal Drug Transport with Ussing Chamber System Incorporating Freshly Isolated Human Jejunum, 2020, published in Drug Metabolism and Disposition
  • Lectin drug conjugate therapy for colorectal cancer, 2020, published in Cancer Science
  • Conversion hepatectomy for hepatocellular carcinoma with main portal vein tumour thrombus after lenvatinib treatment: A case report, 2021, published in World Journal of Hepatology
  • Laparoscopic surgery for diverticular colovesical fistula: single-center experience of 11 cases, 2020, published in BMC Research Notes
  • Glycan expression profile of signet ring cell gastric cancer cells and potential applicability of rBC2LCN-targeted lectin drug conjugate therapy, 2022, published in Gastric Cancer

Best Publications

  • Extraction, Purification and Properties of Aequorin, a Bioluminescent Protein from the Luminous Hydromedusan, Aequorea

    Osamu Shimomura;Osamu Shimomura;Frank H. Johnson;Frank H. Johnson;Yo Saiga;Yo Saiga

  • A first-order liquid–liquid phase transition in phosphorus

    Yoshinori Katayama;Takeshi Mizutani;Wataru Utsumi;Osamu Shimomura

  • Stability of the wurtzite-type structure under high pressure: GaN and InN.

    Masaki Ueno;Minoru Yoshida;Akifumi Onodera;Osamu Shimomura

  • Intermolecular energy transfer in the bioluminescent system of Aequorea

    Hiroshi Morise;Osamu Shimomura;Frank H. Johnson;John Winant

  • Structure of the chromophore of Aequorea green fluorescent protein

    O. Shimomura

  • The crystal structure of the photoprotein aequorin at 2.3 Å resolution

    James F. Head;Satoshi Inouye;Katsunori Teranishi;Osamu Shimomura;Osamu Shimomura

  • Bioluminescence: Chemical Principles and Methods

    Osamu Shimomura

  • High-pressure in situ x-ray-diffraction study of the phase transformation from graphite to hexagonal diamond at room temperature.

    Takehiko Yagi;Wataru Utsumi;Masa-aki Yamakata;Takumi Kikegawa

  • Semi-synthetic aequorins with improved sensitivity to Ca2+ ions

    O Shimomura;B Musicki;Y Kishi

  • Regeneration of the photoprotein aequorin.

    Osamu Shimomura;Frank H. Johnson

  • The discovery of aequorin and green fluorescent protein

    O. Shimomura

  • Quantum efficiency of Cypridina luminescence, with a note on that of Aequorea†

    Frank H. Johnson;Osamu Shimomura;Yo Saiga;Lewis C. Gershman

  • Semi-synthetic aequorin. An improved tool for the measurement of calcium ion concentration.

    O Shimomura;O Shimomura;B Musicki;Y Kishi

  • Discovery of green fluorescent protein (GFP) (Nobel Lecture).

    Osamu Shimomura

  • In situ observation of the olivine‐spinel phase transformation in Fe2SiO4 using synchrotron radiation

    Takehiko Yagi;Masaki Akaogi;Osamu Shimomura;Toshihiro Suzuki

  • New high-pressure structural transition of oxygen at 96 GPa associated with metallization in a molecular solid.

    Yuichi Akahama;Haruki Kawamura;Daniel Häusermann;Michael Hanfland

  • The use of Renilla luciferase, Oplophorus luciferase, and apoaequorin as bioluminescent reporter protein in the presence of coelenterazine analogues as substrate.

    Satoshi Inouye;Osamu Shimomura

  • Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase

    Satoshi Inouye;Ken Watanabe;Hideshi Nakamura;Osamu Shimomura

  • Peroxidized coelenterazine, the active group in the photoprotein aequorin.

    Osamu Shimomura;Frank H. Johnson

  • Light-emitting properties of recombinant semisynthetic aequorins and recombinant fluorescein-conjugated aequorin for measuring cellular calcium

    O. Shimomura;O. Shimomura;B. Musicki;Y. Kishi;S. Inouye

  • Calcium binding, quantum yield, and emitting molecule in aequorin bioluminescence.

    Osamu Shimomura;Frank H. Johnson

  • Properties of the bioluminescent protein aequorin.

    Osamu Shimomura;Frank Harris Johnson

  • Recombinant aequorin and recombinant semi-synthetic aequorins. Cellular Ca2+ ion indicators.

    O Shimomura;O Shimomura;S Inouye;B Musicki;Y Kishi

  • Structure of dinoflagellate luciferin and its enzymic and nonenzymic air-oxidation products

    Hideshi Nakamura;Yoshito Kishi;Osamu Shimomura;David Morse

Frequent Co-Authors

Takumi Kikegawa
Takumi Kikegawa High Energy Accelerator Research Organization
Yoshito Kishi
Yoshito Kishi Harvard University
Hideshi Nakamura
Hideshi Nakamura Nagoya University
Toshio Goto
Toshio Goto Nagoya University
Yasuhiko Syono
Yasuhiko Syono Tohoku University
Satoshi Inouye
Satoshi Inouye JNC (Japan)
Takehiko Yagi
Takehiko Yagi University of Tokyo
Roger Y. Tsien
Roger Y. Tsien University of California, San Diego
Takashi Taniguchi
Takashi Taniguchi National Institute for Materials Science
J. Woodland Hastings
J. Woodland Hastings Harvard University

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