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Yasuhisa Sakurai

Yasuhisa Sakurai

D-Index & Metrics

Chemistry

D-Index
86
Citations
30467
World Ranking
2502
National Ranking
138

Overview

Yasuhisa Sakurai is affiliated with Sophia University in Japan and has contributed to research primarily within the domains of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology.

Their main subfields of study include Molecular Biology, Immunology, Oncology, Biomedical Engineering, and Biomaterials. The research focuses on topics such as RNA Interference and Gene Delivery, Immunotherapy and Immune Responses, Advanced biosensing and bioanalysis techniques, Nanoparticle-Based Drug Delivery, Nanoplatforms for cancer theranostics, RNA Research and Splicing, and Immune Cell Function and Interaction.

Frequent coauthors in Yasuhisa Sakurai's work include:

  • Hidetaka Akita
  • Hiroki Tanaka
  • Yuta Nakai
  • Kota Tange
  • Hiroto Hatakeyama

Their research has been published notably in the following venues, with the number of publications in each:

  • Pharmaceutics (7)
  • Journal of Controlled Release (4)
  • Biological and Pharmaceutical Bulletin (3)
  • ACS Nano (2)
  • Advanced Functional Materials (1)

Recent significant papers authored or coauthored by Yasuhisa Sakurai include:

  • "Self-Degradable Lipid-Like Materials Based on "Hydrolysis accelerated by the intra-Particle Enrichment of Reactant (HyPER)" for Messenger RNA Delivery" (2020), published in Advanced Functional Materials
  • "Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles" (2022), published in Advanced Healthcare Materials
  • "Development of lipid-like materials for RNA delivery based on intracellular environment-responsive membrane destabilization and spontaneous collapse" (2020), published in Advanced Drug Delivery Reviews
  • "Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material" (2021), published in Pharmaceutics
  • "Mitochondrial Delivery of an Anticancer Drug Via Systemic Administration Using a Mitochondrial Delivery System That Inhibits the Growth of Drug-Resistant Cancer Engrafted on Mice" (2020), published in Journal of Pharmaceutical Sciences

Best Publications

  • Comb-type grafted hydrogels with rapid deswelling response to temperature changes

    Ryo Yoshida;Katsumi Uchida;Yuzo Kaneko;Kiyotaka Sakai

  • A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly(N-isopropylacrylamide).

    Teruo Okano;Noriko Yamada;Hideaki Sakai;Yasuhisa Sakurai

  • Thermo-responsive polymeric surfaces; control of attachment and detachment of cultured cells

    Noriko Yamada;Teruo Okano;Hideaki Sakai;Fumiko Karikusa

  • Mechanism of cell detachment from temperature-modulated, hydrophilic–hydrophobic polymer surfaces

    Teruo Okano;Noriko Yamada;Minako Okuhara;Hideaki Sakai

  • Doxorubicin-loaded poly(ethylene glycol)–poly(β-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance

    Kazunori Kataoka;Tsuyoshi Matsumoto;Masayuki Yokoyama;Teruo Okano

  • Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate).

    J.E Chung;M Yokoyama;M Yamato;T Aoyagi

  • Development of the polymer micelle carrier system for doxorubicin.

    T Nakanishi;S Fukushima;K Okamoto;M Suzuki

  • Totally Synthetic Polymer Gels Responding to External Glucose Concentration: Their Preparation and Application to On−Off Regulation of Insulin Release

    Kazunori Kataoka;Hiroaki Miyazaki;Masayuki Bunya;Teruo Okano

  • Temperature-Responsive Chromatography Using Poly(N-isopropylacrylamide)-Modified Silica.

    Hideko Kanazawa;Kazuo Yamamoto;Yoshikazu Matsushima;Nobuharu Takai

  • Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood.

    Masayuki Yokoyama;Teruo Okano;Yasuhisa Sakurai;Hisao Ekimoto

  • Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature‐responsive culture surfaces

    Ai Kushida;Masayuki Yamato;Chie Konno;Akihiko Kikuchi

  • Characterization and Anticancer Activity of the Micelle-forming Polymeric Anticancer Drug Adriamycin-conjugated Poly(ethylene glycol)-Poly(aspartic acid) Block Copolymer

    Masayuki Yokoyama;Mizue Miyauchi;Noriko Yamada;Teruo Okano

  • Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-Adriamycin conjugates

    G. Kwon;S. Suwa;M. Yokoyama;T. Okano

  • Micelles based on AB block copolymers of poly(ethylene oxide) and poly(.beta.-benzyl L-aspartate)

    G. Kwon;M. Naito;M. Yokoyama;T. Okano

  • Thermo-responsive polymer nanoparticles with a core-shell micelle structure as site-specific drug carriers

    S Cammas;K Suzuki;C Sone;Y Sakurai

  • Dynamic contact angle measurement of temperature-responsive surface properties for poly(N-isopropylacrylamide) grafted surfaces

    Yoshiyuki G. Takei;Takashi Aoki;Kohei Sanui;Naoya Ogata

  • Temperature-Responsive Interpenetrating Polymer Networks Constructed with Poly(Acrylic Acid) and Poly(N,N-Dimethylacrylamide)

    Takashi Aoki;Masahiko Kawashima;Hiroki Katono;Kohei Sanui

  • Effect of molecular architecture of hydrophobically modified poly(N-isopropylacrylamide) on the formation of thermoresponsive core-shell micellar drug carriers

    J.E Chung;M Yokoyama;T Aoyagi;Y Sakurai

  • Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor

    Masayuki Yokoyama;Shigeto Fukushima;Ryuji Uehara;Kazuya Okamoto

  • Rapid Deswelling Response of Poly(N-isopropylacrylamide) Hydrogels by the Formation of Water Release Channels Using Poly(ethylene oxide) Graft Chains

    Yuzo Kaneko;Satoki Nakamura;Kiyotaka Sakai;Takao Aoyagi

Frequent Co-Authors

Kazunori Kataoka
Kazunori Kataoka University of Tokyo
Naoya Ogata
Naoya Ogata Sophia University
Kohei Sanui
Kohei Sanui Sophia University
Akihiko Kikuchi
Akihiko Kikuchi Tokyo University of Science
Teruo Okano
Teruo Okano Tokyo Women's Medical University
Kiyotaka Sakai
Kiyotaka Sakai Waseda University
Nobuhiko Yui
Nobuhiko Yui Tokyo Medical and Dental University
Ryo Yoshida
Ryo Yoshida University of Tokyo
Takao Aoyagi
Takao Aoyagi Nihon University
Shohei Inoue
Shohei Inoue Tokyo University of Science

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