Thomas M. Keane mostly deals with Genetics, Genomics, Gene, Genome and Computational biology. In his research, Thomas M. Keane undertakes multidisciplinary study on Genetics and Telomere-binding protein. His work in Genomics addresses issues such as Genetic variation, which are connected to fields such as Genetic variability, Genetic association and Human genetic variation.
His study in the field of Quantitative trait locus and Antigenic variation also crosses realms of Plasmodium vivax, Plasmodium and Plasmodium knowlesi. His Computational biology research is multidisciplinary, incorporating perspectives in Reference genome and 1000 Genomes Project. Thomas M. Keane has included themes like Exome sequencing, Genome-wide association study and Human genome, Genomic Structural Variation, Copy-number variation in his 1000 Genomes Project study.
Thomas M. Keane focuses on Genetics, Genome, Gene, Genomics and Computational biology. Thomas M. Keane interconnects Chromosome and Inbred strain in the investigation of issues within Genome. His Gene research includes elements of Microbiology and Virology.
His research combines Genetic variation and Genomics. The Genetic variation study combines topics in areas such as Structural variation, Genome-wide association study and Genetic association. The study incorporates disciplines such as Personal genomics, Human genome, Contig, Sequence assembly and 1000 Genomes Project in addition to Computational biology.
His primary scientific interests are in Genome, Genetics, Retrotransposon, Gene and Chromosome. Thomas M. Keane has researched Genome in several fields, including Clade, Recombination, Homologous recombination, Annotation and Computational biology. His Computational biology study deals with Contig intersecting with Chromosome painting, Genome rearrangement and Pacific biosciences.
His Genetics study integrates concerns from other disciplines, such as Neuronal migration and Disease. His biological study spans a wide range of topics, including Parkinson's disease and Pars compacta. As a member of one scientific family, Thomas M. Keane mostly works in the field of Chromosome, focusing on Genome evolution and, on occasion, Evolutionary biology.
His primary areas of investigation include Genome, Retrotransposon, Genetics, European Nucleotide Archive and World Wide Web. Thomas M. Keane combines subjects such as Chromosome and Mitochondrial DNA with his study of Genome. His Chromosome study incorporates themes from Genome evolution, Phylogenetics, Mus pahari and Phylogenetic tree.
His study in Retrotransposon is interdisciplinary in nature, drawing from both Evolutionary biology and Strain. His work on Genetics deals in particular with Haplotype, Laboratory mouse, Transposable element, Gene and Reference genome. His European Nucleotide Archive study frequently draws parallels with other fields, such as Sequencing data.
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A global reference for human genetic variation.
Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin.
(2015)
A global reference for human genetic variation
Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin.
PMC (2015)
Mouse genomic variation and its effect on phenotypes and gene regulation
T M Keane;L Goodstadt;P Danecek;M A White.
Nature (2011)
Assessment of methods for amino acid matrix selection and their use on empirical data shows that ad hoc assumptions for choice of matrix are not justified
Thomas M Keane;Christopher J Creevey;Melissa M Pentony;Thomas J Naughton.
BMC Evolutionary Biology (2006)
Mapping copy number variation by population-scale genome sequencing
Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker.
(2011)
A map of human genome variation from population-scale sequencing
Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley.
(2010)
Assessing the gene space in draft genomes
Genis Parra;Keith Bradnam;Zemin Ning;Thomas Keane.
Nucleic Acids Research (2009)
ABACAS: algorithm-based automatic contiguation of assembled sequences
Samuel A. Assefa;Thomas M. Keane;Thomas D. Otto;Chris I Newbold.
Bioinformatics (2009)
The genome of the simian and human malaria parasite Plasmodium knowlesi
A. Pain;U. Böhme;A. E. Berry;K. Mungall.
Nature (2008)
New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq
Thomas D. Otto;Daniel Wilinski;Sammy Assefa;Thomas M. Keane.
Molecular Microbiology (2010)
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