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Biology and Biochemistry

D-Index
67
Citations
34066
World Ranking
8033
National Ranking
3641

Overview

Thomas F. Schilling is affiliated with the University of California, Irvine in the United States. Their research primarily falls within the field of Biochemistry, Genetics, and Molecular Biology, with a strong focus on Molecular Biology. Additional subfields include Cell Biology, Orthopedics and Sports Medicine, Cancer Research, and Surgery.

The scientist's work spans several key topics, including:

  • Developmental Biology and Gene Regulation
  • Connexins and lens biology
  • Congenital heart defects research
  • Tendon Structure and Treatment
  • Zebrafish Biomedical Research Applications
  • RNA Research and Splicing
  • MicroRNA in disease regulation

Frequent co-authors in Schilling's research include:

  • Irene Vorontsova
  • James E. Hall
  • Eberhard Feess
  • Pierre Le Pabic
  • David Tatarakis

Publications have appeared regularly in several venues, with the highest number of papers published in:

  • Development
  • bioRxiv (Cold Spring Harbor Laboratory)
  • AEA Randomized Controlled Trials
  • Developmental Dynamics
  • Biophysical Journal

Selected recent papers highlight a focus on developmental biology, zebrafish models, and tissue regeneration:

  • Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development, 2021, Cell Reports
  • Zebrafish endochondral growth zones as they relate to human bone size, shape and disease, 2022, Frontiers in Endocrinology
  • Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling, 2020, Current Biology
  • Optical development in the zebrafish eye lens, 2020, The FASEB Journal
  • In vivo macromolecular crowding is differentially modulated by aquaporin 0 in zebrafish lens: Insights from a nanoenvironment sensor and spectral imaging, 2022, Science Advances

The research covers zebrafish as a model organism extensively, with investigations into cranial neural crest lineage decisions, skeletal growth zones, tendon regeneration, eye lens development, and molecular crowding within the lens microenvironment. These diverse topics intersect developmental biology, orthopedics, and molecular mechanisms in vertebrate models.

The scholar's profile reflects multidisciplinary work linking molecular biology approaches with developmental systems and biomedical applications focused on tissue structure, regeneration, and disease modeling.

Best Publications

  • Stages of embryonic development of the zebrafish.

    Charles B. Kimmel;William W. Ballard;Seth R. Kimmel;Bonnie Ullmann

  • Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos

    C. Thisse;B. Thisse;T.F. Schilling;J.H. Postlethwait

  • Origin and organization of the zebrafish fate map.

    C.B. Kimmel;R.M. Warga;T.F. Schilling

  • Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo.

    T F Schilling;C B Kimmel

  • A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery

    Patrick Meybohm;Berthold Bein;Oana Brosteanu;Jochen Cremer

  • Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.

    Ary Serpa Neto;Sabrine N.T. Hemmes;Carmen S.V. Barbas;Martin Beiderlinden

  • Small-molecule-directed nanoparticle assembly towards stimuli-responsive nanocomposites

    Yue Zhao;Kari Thorkelsson;Alexander J. Mastroianni;Alexander J. Mastroianni;Thomas Schilling

  • Musculoskeletal patterning in the pharyngeal segments of the zebrafish embryo

    Thomas F. Schilling;Charles B. Kimmel

  • The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain.

    Gerrit Begemann;Thomas F. Schilling;Thomas F. Schilling;Gerd-Jörg Rauch;Robert Geisler

  • Jaw and branchial arch mutants in zebrafish I: branchial arches

    T. F. Schilling;T. Piotrowski;H. Grandel;M. Brand

  • Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis

    Ary Serpa Neto;Ary Serpa Neto;Sabrine N.T. Hemmes;Carmen S.V. Barbas;Martin Beiderlinden

  • Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.

    Naoyuki Wada;Yashar Javidan;Sarah Nelson;Thomas J. Carney

  • Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos.

    Louise A Brown;Adam R.F Rodaway;Thomas F Schilling;Trevor Jowett

  • Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation

    T. Piotrowski;T. F. Schilling;M. Brand;Y. J. Jiang

  • The pulmonary immune effects of mechanical ventilation in patients undergoing thoracic surgery.

    Thomas Schilling;Alf Kozian;Christof Huth;Frank Bühling

  • sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.

    Craig T. Miller;Thomas F. Schilling;Kyu-Ho Lee;Jewel Parker

  • Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis

    Ary Serpa Neto;Sabrine N.T. Hemmes;Carmen S.V. Barbas;Martin Beiderlinden

  • Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo.

    Richard J White;Qing Nie;Arthur D Lander;Thomas F Schilling

  • lockjaw encodes a zebrafish tfap2a required for early neural crest development.

    Robert D. Knight;Sreelaja Nair;Sarah S. Nelson;Ali Afshar

  • The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans.

    Tatjana Piotrowski;Dae Gwon Ahn;Thomas F. Schilling;Sreelaja Nair

Frequent Co-Authors

Arthur D. Lander
Arthur D. Lander University of California, Irvine
Göran Hedenstierna
Göran Hedenstierna Uppsala University
Charles B. Kimmel
Charles B. Kimmel University of Oregon
Rob Knight
Rob Knight University of California, San Diego
Enrico Gratton
Enrico Gratton University of California, Irvine
Marcus J. Schultz
Marcus J. Schultz University of Amsterdam
Philip W. Ingham
Philip W. Ingham University of Bath
Peter D. Currie
Peter D. Currie Monash University
Robert N. Kelsh
Robert N. Kelsh University of Bath
Paolo Pelosi
Paolo Pelosi University of Genoa

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