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Biology and Biochemistry

D-Index
50
Citations
8503
World Ranking
17689
National Ranking
7254

Overview

Teresa M. Dunn is affiliated with the Uniformed Services University of the Health Sciences in the United States. Their research primarily intersects the fields of medicine and biochemistry, genetics, and molecular biology, with a significant focus on molecular biology, neurology, genetics, cell biology, and cellular and molecular neuroscience.

Their work extensively covers several specialized topics, including:

  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Cellular transport and secretion
  • Sphingolipid Metabolism and Signaling
  • Hereditary Neurological Disorders
  • Lipid Membrane Structure and Behavior
  • Endoplasmic Reticulum Stress and Disease

They have contributed research published in a variety of academic venues, demonstrating a consistent involvement in journals related to neurology and molecular biology. Frequent publication venues include:

  • Journal of Neurology Neurosurgery & Psychiatry
  • Journal of Neuromuscular Diseases
  • The FASEB Journal
  • Nature Medicine
  • Nature Structural & Molecular Biology

Among their recent papers are the following:

  • Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis, 2021, Nature Medicine
  • Structural insights into the regulation of human serine palmitoyltransferase complexes, 2021, Nature Structural & Molecular Biology
  • ORMDL3 and Asthma: Linking Sphingolipid Regulation to Altered T Cell Function, 2020, Frontiers in Immunology
  • Unregulated Sphingolipid Biosynthesis in Gene-Edited Arabidopsis ORM Mutants Results in Nonviable Seeds with Strongly Reduced Oil Content, 2020, The Plant Cell
  • Recurrent de novo SPTLC2 variant causes childhood-onset amyotrophic lateral sclerosis (ALS) by excess sphingolipid synthesis, 2023, Journal of Neurology Neurosurgery & Psychiatry

Their collaborations include frequent co-authors who have contributed to multiple publications together. Prominent collaborators are:

  • Kenneth Gable
  • Sita D. Gupta
  • Payam Mohassel
  • Sandra Donkervoort
  • Carsten G. Bönnemann

Best Publications

  • An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression

    Teresa M. Dunn;Steven Hahn;Sharon Ogden;Robert F. Schleif

  • HYDROXYLATION OF SACCHAROMYCES CEREVISIAE CERAMIDES REQUIRES SUR2P AND SCS7P

    Dale Haak;Ken Gable;Troy Beeler;Teresa Dunn

  • Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities

    Gongshe Han;Sita D. Gupta;Kenneth Gable;Somashekarappa Niranjanakumari

  • The Saccharomyces cerevisiae TSC10/YBR265w Gene Encoding 3-Ketosphinganine Reductase Is Identified in a Screen for Temperature-sensitive Suppressors of the Ca2+-sensitive csg2Δ Mutant

    Troy Beeler;Dagmar Bacikova;Ken Gable;Lisa Hopkins

  • An introduction to plant sphingolipids and a review of recent advances in understanding their metabolism and function

    Daniel V. Lynch;Teresa M. Dunn

  • Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.

    Sepp D. Kohlwein;Sandra Eder;Chan-Seok Oh;Charles E. Martin

  • Regulation of cellular Ca2+ by yeast vacuoles.

    T Dunn;K Gable;T Beeler

  • Tsc3p Is an 80-Amino Acid Protein Associated with Serine Palmitoyltransferase and Required for Optimal Enzyme Activity

    Ken Gable;Harry Slife;Dagmar Bacikova;Erin Monaghan

  • An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense in Arabidopsis

    Wenming Wang;Xiaohua Yang;Samantha Tangchaiburana;Roland Ndeh

  • Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily.

    Dadin Fu;Troy J. Beeler;Teresa M. Dunn

  • A post-genomic approach to understanding sphingolipid metabolism in Arabidopsis thaliana.

    Teresa M. Dunn;Daniel V. Lynch;Louise V. Michaelson;Johnathan A. Napier

  • Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action

    Kristin Baetz;Lianne McHardy;Ken Gable;Tamsin Tarling

  • Metabolic Response to Iron Deficiency in Saccharomyces cerevisiae

    Minoo Shakoury-Elizeh;Olga Protchenko;Alvin Berger;James Cox

  • SUR1 (CSG1/BCL21), a gene necessary for growth of Saccharomyces cerevisiae in the presence of high Ca2+ concentrations at 37 degrees C, is required for mannosylation of inositolphosphorylceramide.

    T. J. Beeler;D. Fu;J. Rivera;E. Monaghan

  • Plant sphingolipids: Function follows form

    Jonathan E Markham;Daniel V Lynch;Johnathan A Napier;Teresa M Dunn

  • The Essential Nature of Sphingolipids in Plants as Revealed by the Functional Identification and Characterization of the Arabidopsis LCB1 Subunit of Serine Palmitoyltransferase

    Ming Chen;Gongshe Han;Charles R. Dietrich;Teresa M. Dunn

  • Members of the Arabidopsis FAE1-like 3-Ketoacyl-CoA Synthase Gene Family Substitute for the Elop Proteins of Saccharomyces cerevisiae

    Shilpi Paul;Kenneth Gable;Frédéric Beaudoin;Edgar Cahoon

  • A novel protein, CSG2p, is required for Ca2+ regulation in Saccharomyces cerevisiae.

    Troy Beeler;Kenneth Gable;Chun Zhao;Teresa Dunn

  • Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity.

    Chun Zhao;T. Beeler;T. Dunn

  • Sphingolipid biosynthesis in man and microbes.

    Peter J Harrison;Teresa M Dunn;Dominic J Campopiano

Frequent Co-Authors

Edgar B. Cahoon
Edgar B. Cahoon University of Nebraska–Lincoln
Johnathan A. Napier
Johnathan A. Napier Rothamsted Research
Richard L. Proia
Richard L. Proia National Institutes of Health
James H. Naismith
James H. Naismith Rosalind Franklin Institute
Sepp D. Kohlwein
Sepp D. Kohlwein University of Graz
Linda J. Harris
Linda J. Harris University of California, Davis
Jacek Bielawski
Jacek Bielawski Medical University of South Carolina
Clifford J. Woolf
Clifford J. Woolf Boston Children's Hospital
Robbie Loewith
Robbie Loewith University of Geneva
Matthew P. Frosch
Matthew P. Frosch Harvard University

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