World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
67
Citations
16037
World Ranking
6895
National Ranking
156

Sijbren Otto publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Sijbren Otto sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 644 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 253 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 179 publications — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Sijbren Otto D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sijbren Otto sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 776 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 647 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 67 D-Index — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Catalysis
  • Biochemistry

Sijbren Otto mainly investigates Dynamic combinatorial chemistry, Nanotechnology, Combinatorial chemistry, Organic chemistry and Stereochemistry. His study connects Computational biology and Dynamic combinatorial chemistry. In his study, Molecular conformation is strongly linked to Replication, which falls under the umbrella field of Nanotechnology.

Sijbren Otto has researched Combinatorial chemistry in several fields, including Disulfide bond and Aqueous solution. His research investigates the connection with Organic chemistry and areas like Medicinal chemistry which intersect with concerns in Enantiomeric excess and Chiral Lewis acid. The concepts of his Stereochemistry study are interwoven with issues in Receptor and Stability constants of complexes.

His most cited work include:

  • Dynamic combinatorial chemistry. (1246 citations)
  • Supramolecular systems chemistry (421 citations)
  • Mechanosensitive self-replication driven by self-organization. (325 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Dynamic combinatorial chemistry, Combinatorial chemistry, Nanotechnology, Molecular recognition and Supramolecular chemistry. His Dynamic combinatorial chemistry research incorporates elements of Theoretical computer science, Receptor, Catalysis, Solid-phase synthesis and Computational biology. The Combinatorial chemistry study combines topics in areas such as Disulfide bond, Molecule, Synthetic Receptors and Aqueous solution.

His work in the fields of Nanotechnology, such as Self-replication, intersects with other areas such as Molecular network and Chemistry. His Molecular recognition research incorporates themes from Stereochemistry, Polymer and Combinatorial Chemistry Techniques. He interconnects Covalent bond, Polymer chemistry and Self-assembly in the investigation of issues within Supramolecular chemistry.

He most often published in these fields:

  • Dynamic combinatorial chemistry (35.06%)
  • Combinatorial chemistry (29.22%)
  • Nanotechnology (26.62%)

What were the highlights of his more recent work (between 2015-2021)?

  • Dynamic combinatorial chemistry (35.06%)
  • Self-replication (9.09%)
  • Nanotechnology (26.62%)

In recent papers he was focusing on the following fields of study:

Sijbren Otto mostly deals with Dynamic combinatorial chemistry, Self-replication, Nanotechnology, Molecule and Supramolecular chemistry. Dynamic combinatorial chemistry is a subfield of Combinatorial chemistry that he investigates. His Self-replication study combines topics in areas such as Evolutionary biology and Distributed computing.

His Nanotechnology research is multidisciplinary, incorporating elements of Amphiphile, Micelle, Data science and Molecular systems. His Molecule research is multidisciplinary, incorporating perspectives in Biophysics, Macromolecule and Molecular dynamics. His Supramolecular chemistry research integrates issues from Covalent bond, Non-covalent interactions and Self-assembly.

Between 2015 and 2021, his most popular works were:

  • Diversification of self-replicating molecules (116 citations)
  • Chemical systems out of equilibrium (56 citations)
  • Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry (34 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Catalysis
  • Biochemistry

His scientific interests lie mostly in Dynamic combinatorial chemistry, Nanotechnology, Self-replication, Covalent bond and Supramolecular chemistry. With his scientific publications, his incorporates both Dynamic combinatorial chemistry and Linear sequence. His studies deal with areas such as Biological system, Computational biology and Random hexamer as well as Nanotechnology.

His Self-replication research includes elements of Data science and Molecular systems. His research in Covalent bond intersects with topics in Antiparallel, Disulfide bond, Functional group and Supramolecular polymers. The various areas that Sijbren Otto examines in his Supramolecular chemistry study include Self-assembly, Stereochemistry, Chemical physics and Autocatalysis.

Best Publications

  • Dynamic combinatorial chemistry.

    Peter T Corbett;Julien Leclaire;Laurent Vial;Kevin R West

  • Supramolecular systems chemistry

    Elio Mattia;Sijbren Otto

  • Mechanosensitive self-replication driven by self-organization.

    Jacqui M. A. Carnall;Christopher A. Waudby;Christopher A. Waudby;Ana M. Belenguer;Marc C. A. Stuart

  • Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry

    Jianwei Li;Piotr Nowak;Sijbren Otto

  • Selection and Amplification of Hosts From Dynamic Combinatorial Libraries of Macrocyclic Disulfides

    Sijbren Otto;Ricardo L. E. Furlan;Jeremy K. M. Sanders

  • Hydrophobic interactions and chemical reactivity

    Sijbren Otto;Jan B. F. N. Engberts

  • Amplification of Acetylcholine-Binding Catenanes from Dynamic Combinatorial Libraries

    Ruby T S Lam;Ana M Belenguer;Sarah L Roberts;Christoph A Naumann

  • Dynamic Combinatorial Libraries of Macrocyclic Disulfides in Water

    Sijbren Otto;Ricardo L.E. Furlan;Jeremy K.M. Sanders

  • Diels-Alder reactions in water

    Sijbren Otto;Jan B.F.N. Engberts

  • Lewis acid catalysis of a Diels-Alder reaction in water

    Sijbren Otto;Federica Bertoncin;Jan B. F. N. Engberts

  • Dynamic combinatorial libraries: new opportunities in systems chemistry.

    Rosemary A. R. Hunt;Sijbren Otto

  • Million-fold acceleration of a Diels-Alder reaction due to combined Lewis acid and micellar catalysis in water

    Sijbren Otto;Jan B. F. N. Engberts;Jan C. T. Kwak

  • Dynamic Combinatorial Optimization of a Neutral Receptor That Binds Inorganic Anions in Aqueous Solution

    Sijbren Otto;Stefan Kubik

  • Diversification of self-replicating molecules

    Jan W. Sadownik;Elio Mattia;Piotr Nowak;Sijbren Otto

  • Effects of the Hydrophobicity of the Reactants on Diels-Alder Reactions in Water

    Ale Meijer;Sijbren Otto;Jan B.F.N. Engberts

  • Systems chemistry.

    Unknown

  • Reversible Covalent Chemistry in Drug Delivery

    Kevin R. West;Sijbren Otto

  • Dynamic combinatorial chemistry.

    Sijbren Otto;Ricardo L.E Furlan;Jeremy K.M Sanders

  • Diels-Alder Reactions in Water. Effects of Hydrophobicity and Hydrogen Bonding

    Sijbren Otto;Wilfried Blokzijl;Jan B.F.N. Engberts

  • A systematic study of ligand effects on a Lewis-acid-catalyzed Diels-Alder reaction in water. Water-enhanced enantioselectivity

    Sijbren Otto;Jan B. F. N. Engberts

  • Dynamic Molecular Networks: From Synthetic Receptors to Self-Replicators

    Sijbren Otto

  • From self-replication to replicator systems en route to de novo life

    Paul Adamski;Marcel Eleveld;Ankush Sood;Ádám Kun;Ádám Kun

Frequent Co-Authors

Jeremy K. M. Sanders
Jeremy K. M. Sanders University of Cambridge
Jan B. F. N. Engberts
Jan B. F. N. Engberts University of Groningen
Marc C. A. Stuart
Marc C. A. Stuart University of Groningen
Jasper van der Gucht
Jasper van der Gucht Wageningen University & Research
Steven L. Regen
Steven L. Regen Lehigh University
David C. Sherrington
David C. Sherrington University of Strathclyde
Peter A. G. Cormack
Peter A. G. Cormack University of Strathclyde
Andrew D. Bond
Andrew D. Bond University of Cambridge
Eörs Szathmáry
Eörs Szathmáry Parmenides Foundation
Kevin Pagel
Kevin Pagel Freie Universität Berlin

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