Sherry F. Queener

Overview

Best Publications

• Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates.

  Aleem Gangjee;Yibin Zeng;Tina Talreja;John J. McGuire

  368
  Citations

• 2,4-Diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases

  Aleem Gangjee;Anil Vasudevan;Sherry F. Queener;Roy L. Kisliuk

  154
  Citations

• Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs.

  M. C. Broughton;Sherry Queener

  145
  Citations

• Design, Synthesis, Computational Prediction, and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase from Pneumocystis carinii

  Malin Graffner-Nordberg;Karin Kolmodin;Johan Aqvist;Sherry F. Queener

  135
  Citations

• Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent.

  Aleem Gangjee;Jianming Yu;John J. Mcguire;Vivian Cody

  132
  Citations

• Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: synthesis and biological activities of 2,4-diamino-5-methyl-6-[(monosubstituted anilino)methyl] pyrido[2,3-d]pyrimidines.

  Aleem Gangjee;Ona Adair;Sherry F. Queener

  131
  Citations

• Synthesis of new 2,4-Diaminopyrido[2,3-d]pyrimidine and 2,4-Diaminopyrrolo[2,3-d]pyrimidine inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase.

  Andre Rosowsky;Han Chen;Hongning Fu;Sherry F. Queener

  125
  Citations

• Control of gene expression in carbohydrate, pyrimidine and DNA metabolism

  George Weber;Sherry F. Queener;John A. Ferdinandus

  122
  Citations

• Dihydrouracil Dehydrogenase Activity in Normal, Differentiating, and Regenerating Liver and in Hepatomas

  Sherry F. Queener;Harold P. Morris;George Weber

  112
  Citations

• Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase

  L. C. Chio;Sherry Queener

  111
  Citations

• Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.

  Aleem Gangjee;Rajesh Devraj;John J. McGuire;Roy L. Kisliuk

  110
  Citations

• Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation.

  Robert C. Reynolds;Shiela R. Campbell;Ralph G. Fairchild;Roy L. Kisliuk

  108
  Citations

• 2,4-Diaminothieno[2,3-d]pyrimidine analogues of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

  Andre Rosowsky;Clara E. Mota;Joel E. Wright;James H. Freisheim

  100
  Citations

• New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii

  Sherry F. Queener

  98
  Citations

• Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines.

  Aleem Gangjee;Anup Vidwans;Elfatih Elzein;John J. Mcguire

  96
  Citations

• Design, Synthesis, and Antifolate Activity of New Analogues of Piritrexim and Other Diaminopyrimidine Dihydrofolate Reductase Inhibitors with ω-Carboxyalkoxy or ω-Carboxy-1-alkynyl Substitution in the Side Chain

  David C. M. Chan;Hongning Fu;Ronald A. Forsch;Sherry F. Queener

  88
  Citations

• Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.

  Vivian Cody;Nikolai Galitsky;Dawn Rak;Joseph R. Luft

  88
  Citations

• Anthranilate synthase enzyme system and complementation in Pseudomonas species.

  Sherry Queener;I. C. Gunsalus

  87
  Citations

• Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents.

  Aleem Gangjee;Anup P. Vidwans;Anil Vasudevan;Sherry F. Queener

  86
  Citations

• On the lipolytic action of parathyroid hormone in man

  Tushar K. Sinha;Payup Thajchayapong;Sherry F. Queener;Donald O. Allen

  84
  Citations