World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10961
World Ranking
13289
National Ranking
453

Overview

Robert C. Miller is affiliated with the University of British Columbia in Canada and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research encompasses a variety of subfields including molecular biology, materials chemistry, biophysics, spectroscopy, and bioengineering.

Their work focuses on several main topics such as enzyme structure and function, protein structure and dynamics, and advanced fluorescence microscopy techniques. Additional topics include biochemical and molecular research, analytical chemistry and sensors, photoreceptor and optogenetics research, and mass spectrometry techniques and applications.

Recent publications by Robert C. Miller and collaborators illustrate engagement with experimental methods in biophysical chemistry and protein science. Notable papers include:

  • "High-pressure small-angle X-ray scattering cell for biological solutions and soft materials" (2020), published in the Journal of Applied Crystallography
  • "FRET Analysis of Ionic Strength Sensors in the Hofmeister Series of Salt Solutions Using Fluorescence Lifetime Measurements" (2020), published in The Journal of Physical Chemistry B
  • "Fluorescence depolarization dynamics of ionic strength sensors using time-resolved anisotropy" (2021), published in Biophysical Journal
  • "Inline small-angle X-ray scattering-coupled chromatography under extreme hydrostatic pressure" (2022), published in Protein Science
  • "Molecular Brightness Approach for FRET Analysis of Donor-Linker-Acceptor Constructs at the Single Molecule Level: A Concept" (2021), published in Frontiers in Molecular Biosciences

Frequent publication venues for Miller include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Physical Chemistry B, Biophysical Journal, Structural Dynamics, and Journal of Applied Crystallography. These reflect diverse interests in both experimental and theoretical aspects of molecular and structural biology.

Collaborations appear consistent over time, with frequent co-authors comprising Nozomi Ando, Cody Aplin, Taryn M. Kay, Ahmed A. Heikal, and Arnold J. Boersma. These partnerships suggest an interdisciplinary approach integrating expertise from related fields.

Best Publications

  • Domains in microbial beta-1, 4-glycanases: sequence conservation, function, and enzyme families.

    N. R. Gilkes;B. Henrissat;D. G. Kilburn;R. C. Miller

  • Precise excision of the cellulose binding domains from two Cellulomonas fimi cellulases by a homologous protease and the effect on catalysis.

    N R Gilkes;R A Warren;R C Miller;D G Kilburn

  • Non–Hydrolytic Disruption of Cellulose Fibres by the Binding Domain of a Bacterial Cellulase

    Neena Din;Neil R. Gilkes;Bahar Tekant;Robert C. Miller

  • Stereoselective hydrolysis catalyzed by related beta-1,4-glucanases and beta-1,4-xylanases.

    J Gebler;N R Gilkes;M Claeyssens;D B Wilson

  • The adsorption of a bacterial cellulase and its two isolated domains to crystalline cellulose.

    N. R. Gilkes;E. Jervis;B. Henrissat;B. Tekant

  • Characterization and structure of an endodglucanase gene of Cellulomonas fimi

    R. Anthony J. Warren;Douglas G. Kilburn;Robert C. Miller

  • Structure of the gene encoding the exoglucanase of Cellulomonas fimi

    G. O'Neill;S.H. Goh;R.A.J. Warren;D.G. Kilburn

  • C1-Cx revisited: intramolecular synergism in a cellulase.

    N Din;H G Damude;N R Gilkes;R C Miller

  • Mode of action and substrate specificities of cellulases from cloned bacterial genes.

    N R Gilkes;M L Langsford;D G Kilburn;R C Miller

  • Glycosylation of bacterial cellulases prevents proteolytic cleavage between functional domains

    M.L. Langsford;N.R. Gilkes;B. Singh;B. Moser

  • Cellulose binding fusion proteins having a substrate binding region of cellulase

    Douglas G. Kilburn;Robert C. Miller;Richard A. J. Warren;Neil R. Gilkes

  • Deletion of the linker connecting the catalytic and cellulose-binding domains of endoglucanase A (CenA) of Cellulomonas fimi alters its conformation and catalytic activity.

    H. Shen;M. Schmuck;I. Pilz;N. R. Gilkes

  • The cellulose-binding domain of endoglucanase A (CenA) from Cellulomonas fimi: evidence for the involvement of tryptophan residues in binding.

    Neena Din;Ian J. Forsythe;Leslie D. Burtnick;Neil R. Gilkes

  • Molecular cloning of a Cellulomonas fimi cellulose gene in Escherichia coli.

    D.J. Whittle;D.G. Kilburn;R.A.J. Warren;R.C. Miller

  • The cellulose-binding domains of cellulases: tools for biotechnology

    Edgar Ong;Jeffrey M. Greenwood;Neil R. Gilkes;Douglas G. Kilburn

  • The Cellulase System of Cellulomonas fimi

    Maureen L. Langsford;N. R. Gilkes;W. W. Wakarchuk;D. G. Kilburn

  • Comparison of a fungal (family I) and bacterial (family II) cellulose-binding domain.

    P Tomme;D P Driver;E A Amandoron;R C Miller

  • Cellulose-binding polypeptides from Cellulomonas fimi: endoglucanase D (CenD), a family A beta-1,4-glucanase.

    A. Meinke;N. R. Gilkes;D. G. Kilburn;R. C. Miller

  • Enzyme immobilization using the cellulose-binding domain of a Cellulomonas fimi exoglucanase

    Edgar Ong;Neil R. Gilkes;R. Antony J. Warren;Robert C. Miller

  • Enzyme immobilization using a cellulose-binding domain: Properties of a β-glucosidase fusion protein

    Edgar Ong;Neil R. Gilkes;Robert C. Miller;R. Antony

Frequent Co-Authors

Douglas G. Kilburn
Douglas G. Kilburn University of British Columbia
Neil R. Gilkes
Neil R. Gilkes University of British Columbia
R A Warren
R A Warren University of British Columbia
Warren W. Wakarchuk
Warren W. Wakarchuk University of Alberta
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Stephen G. Withers
Stephen G. Withers University of British Columbia
Bernhard Moser
Bernhard Moser Cardiff University
Marc Claeyssens
Marc Claeyssens Ghent University
John N. Saddler
John N. Saddler University of British Columbia
Henri Chanzy
Henri Chanzy Joseph Fourier University

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