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Chemistry

D-Index
49
Citations
7481
World Ranking
14951
National Ranking
594

Overview

Rafael Gómez is affiliated with the University of Alcalá in Spain and has contributed extensively to research in materials science and biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, polymers and plastics, organic chemistry, biomaterials, and pollution.

Their research covers a variety of scientific topics, with significant emphasis on dendrimers and hyperbranched polymers, RNA interference and gene delivery, advanced biosensing and bioanalysis techniques, antimicrobial agents and applications, HIV research and treatment, microplastics and plastic pollution, and ferrocene chemistry and applications.

Frequent collaborators include F. Javier de la Mata, Maria Bryszewska, Javier Sánchez-Nieves, Paula Ortega, and Jesús Cano.

Rafael Gómez has published numerous papers in prominent scientific journals. Recent works include:

  • Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells, 2020, Antioxidants
  • The Antibacterial Effect of PEGylated Carbosilane Dendrimers on P. aeruginosa Alone and in Combination with Phage-Derived Endolysin, 2022, International Journal of Molecular Sciences
  • Copper (II) Metallodendrimers Combined with Pro-Apoptotic siRNAs as a Promising Strategy Against Breast Cancer Cells, 2020, Pharmaceutics
  • Gold Nanoparticles Crossing Blood-Brain Barrier Prevent HSV-1 Infection and Reduce Herpes Associated Amyloid-βsecretion, 2020, Journal of Clinical Medicine
  • pH-Sensitive Dendrimersomes of Hybrid Triazine-Carbosilane Dendritic Amphiphiles-Smart Vehicles for Drug Delivery, 2020, Nanomaterials

These publications reflect work in drug delivery systems, cancer therapy, antibacterial treatments, and nanomedicine applications.

Rafael Gómez's research is often published in journals such as Pharmaceutics, International Journal of Molecular Sciences, Scientific Reports, Journal of Nanobiotechnology, and Journal of Inorganic Biochemistry.

Best Publications

  • Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes.

    Nick Weber;Paula Ortega;Paula Ortega;Maria Isabel Clemente;Maria Isabel Clemente;Dzmitry Shcharbin

  • Water‐Soluble Carbosilane Dendrimers: Synthesis Biocompatibility and Complexation with Oligonucleotides; Evaluation for Medical Applications

    Jesus F. Bermejo;Paula Ortega;Louis Chonco;Ramon Eritja

  • Nanosystems as Vehicles for the Delivery of Antimicrobial Peptides (AMPs)

    Ángela Martin-Serrano;Rafael Gómez;Paula Ortega;F Javier de la Mata

  • Mononuclear and Dendritic Nickel(II) Complexes Containing N,N‘-Iminopyridine Chelating Ligands: Generation Effects on the Catalytic Oligomerization and Polymerization of Ethylene†

    José M. Benito;Ernesto De Jesus;F. Javier De La Mata;Juan C. Flores

  • Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells.

    Leanne Ambrosio;Monica Argenziano;Marie Angèle Cucci;Margherita Grattarola

  • Synthesis and Reactivity of [(Amidosilyl)cyclopentadienyl]titanium and -zirconium Complexes. X-ray Molecular Structure of [Zr{η5:η1-C5H4SiMe2(μ-O)}Cl2{H2N(CHMe)Ph}]2†

    Santiago Ciruelos;Tomás Cuenca;Rafael Gómez;‡ Pilar Gómez-Sal

  • Amine and ammonium functionalization of chloromethylsilane-ended dendrimers. Antimicrobial activity studies.

    Paula Ortega;Jose Luis Copa-Patiño;Ma Angeles Muñoz-Fernandez;Juan Soliveri

  • Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (B). Efficiency of pharmacological action

    Volha Dzmitruk;Aleksandra Szulc;Dzmitry Shcharbin;Anna Janaszewska

  • Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy

    Daniel Sepúlveda-Crespo;Rafael Gómez;Francisco Javier De La Mata;José Luis Jiménez

  • Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (A). Mechanisms of interaction.

    Maksim Ionov;Joanna Lazniewska;Volha Dzmitruk;Inessa Halets

  • Carbosilane cationic dendrimers synthesized by thiol–ene click chemistry and their use as antibacterial agents

    Elena Fuentes-Paniagua;José Manuel Hernández-Ros;María Sánchez-Milla;M. Alejandra Camero

  • Synthesis and anticancer activity of carbosilane metallodendrimers based on arene ruthenium(ii) complexes.

    Marta Maroto-Díaz;Benelita T. Elie;Pilar Gómez-Sal;Jorge Pérez-Serrano

  • Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins

    Louis Chonco;Jesus F. Bermejo-Martín;Paula Ortega;Dzmitry Shcharbin

  • Highly Efficient Transfection of Rat Cortical Neurons Using Carbosilane Dendrimers Unveils a Neuroprotective Role for HIF-1α in Early Chemical Hypoxia-Mediated Neurotoxicity

    Inmaculada Posadas;Inmaculada Posadas;Beatriz López-Hernández;Beatriz López-Hernández;Maria Isabel Clemente;Maria Isabel Clemente;Jose Luis Jiménez;Jose Luis Jiménez;Jose Luis Jiménez

  • Hyperbranched polymers versus dendrimers containing a carbosilane framework and terminal ammonium groups as antimicrobial agents

    Paula Ortega;Beatriz Macarena Cobaleda;Jose Manuel Hernández-Ros;Elena Fuentes-Paniagua

  • Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16

    Daniel Sepúlveda-Crespo;María Jesús Serramía;Andrew M. Tager;Andrew M. Tager;Vladimir Vrbanac;Vladimir Vrbanac

  • Water-stable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents.

    Beatriz Rasines;José Manuel Hernández-Ros;Natividad de las Cuevas;José Luis Copa-Patiño

  • Synthesis of Carbosilane Dendrimers Containing Peripheral (Cyclopentadienyl)(aryloxy)titanium(IV) Units

    Silvia Arévalo;Ernesto de Jesús;F. Javier de la Mata;and Juan C. Flores

  • Mono(η-cyclopentadienyl)benzamidinato alkyl compounds of titanium and zirconium

    Rafael Gómez;Robbert Duchateau;Alexander N. Chernega;Auke Meetsma

  • Synthesis, structure and molecular modelling of anionic carbosilane dendrimers

    Beatriz Rasines;Javier Sánchez-Nieves;Massimo Maiolo;Marek Maly

  • Generation effects on the microstructure and product distribution in ethylene polymerization promoted by dendritic nickel catalysts

    José M. Benito;Ernesto de Jesús;F. Javier de la Mata;Juan C. Flores

  • Novel Water-Soluble Carbosilane Dendrimers: Synthesis and Biocompatibility

    Paula Ortega;Jesus F. Bermejo;Louis Chonco;Ernesto de Jesus

Frequent Co-Authors

Maria Bryszewska
Maria Bryszewska University of Łódź
Jose L. Jimenez
Jose L. Jimenez University of Colorado Boulder
María Luisa Marina
María Luisa Marina University of Alcalá
M. Francesca Ottaviani
M. Francesca Ottaviani University of Urbino
Malcolm L. H. Green
Malcolm L. H. Green University of Oxford
Angel L. Corbí
Angel L. Corbí Spanish National Research Council
Ramon Eritja
Ramon Eritja Spanish National Research Council
Manuel Leal
Manuel Leal University of Missouri
Andrew M. Tager
Andrew M. Tager Harvard University
Valentín Ceña
Valentín Ceña University of Castilla-La Mancha

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