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D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
12579
World Ranking
19207
National Ranking
75

Overview

Marie Loh is affiliated with Nanyang Technological University in Singapore. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology.

The scientist has contributed predominantly to fields such as molecular biology, genetics, physiology, dermatology, and endocrinology, diabetes, and metabolism. Their work covers a range of topics including genetic associations and epidemiology, epigenetics and DNA methylation, dermatology and skin diseases, RNA modifications and cancer, genetic syndromes and imprinting, diabetes, cardiovascular risks and lipoproteins, and cancer-related molecular mechanisms research.

Marie Loh's frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics
  • Nature Communications
  • UNC Libraries
  • Clinical Epigenetics

Recent papers authored or co-authored by Marie Loh include:

  • The trans-ancestral genomic architecture of glycemic traits, 2021, Nature Genetics
  • Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation, 2022, Nature Genetics
  • Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function, 2022, Nature Genetics
  • No evidence for a common blood microbiome based on a population study of 9,770 healthy humans, 2023, Nature Microbiology
  • DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases, 2022, Nature Communications

Marie Loh collaborates frequently with several scientists, with the most prominent co-authors being:

  • John C. Chambers
  • Jaspal S. Kooner
  • Yik Weng Yew
  • Theresia Mina
  • Hong Kiat Ng

The body of work reflects a strong emphasis on the genetic and epigenetic bases of disease, particularly focusing on diabetes, cardiovascular health, and inflammation-related processes. Through multi-ancestry studies and molecular biology approaches, the research outputs contribute to understanding genomics function and epidemiology across diverse populations.

Best Publications

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

    Simone Wahl;Alexander Drong;Benjamin Lehne;Marie Loh;Marie Loh;Marie Loh

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.

    John C Chambers;Marie Loh;Marie Loh;Marie Loh;Benjamin Lehne;Alexander Drong

  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Anubha Mahajan;Jennifer Wessel;Sara M. Willems;Wei Zhao

  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

    Norihiro Kato;Marie Loh;Marie Loh;Marie Loh;Fumihiko Takeuchi;Niek Verweij

  • A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

    Benjamin Lehne;Alexander W Drong;Marie Loh;Marie Loh;Weihua Zhang;Weihua Zhang

  • Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients

    Valerie Chew;Charlene Tow;Marissa Teo;Hing Lok Wong

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Yingchang Lu;Felix R Day;Stefan Gustafsson;Stefan Gustafsson;Martin L Buchkovich

  • RUNX3 Is Frequently Inactivated by Dual Mechanisms of Protein Mislocalization and Promoter Hypermethylation in Breast Cancer

    Quek Choon Lau;Erna Raja;Manuel Salto-Tellez;Qiang Liu

  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Anne E. Justice;Thomas W. Winkler;Mary F. Feitosa;Misa Graff

  • Directional dominance on stature and cognition in diverse human populations

    Peter K. Joshi;Tonu Esko;Hannele Mattsson;Niina Eklund

  • MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer

    Kin Wai Lai;King Xin Koh;Marie Loh;Kotaro Tada

  • Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells.

    Xiaohong Xu;Yilin Tay;Bernice Sim;Su-In Yoon

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R. Warren;Evangelos Evangelou;Claudia P. Cabrera;He Gao

  • Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3.

    Sing-Huang Tan;Hiroshi Ida;Quek-Choon Lau;Boon-Cher Goh

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)

    HR Warren;E Evangelou;CP Cabrera;H Gao

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

Frequent Co-Authors

John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
Weihua Zhang
Weihua Zhang Imperial College London
Philippe Froguel
Philippe Froguel Imperial College London
Tonu Esko
Tonu Esko University of Tartu
Paul W. Franks
Paul W. Franks Lund University
Paul Elliott
Paul Elliott Imperial College London
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Annette Peters
Annette Peters Ludwig-Maximilians-Universität München

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