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68
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15540
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Overview

Manfred Spraul is affiliated with the University of Aveiro in Portugal. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these areas, their work focuses extensively on Molecular Biology, Epidemiology, Infectious Diseases, Neurology, and Physiology.

Their research topics cover a range of areas including Metabolomics and Mass Spectrometry Studies, Liver Disease Diagnosis and Treatment, Long-Term Effects of COVID-19, Diet and Metabolism Studies, Metabolism and Genetic Disorders, Infectious Encephalopathies and Encephalitis, and COVID-19 Clinical Research Studies.

Manfred Spraul has contributed multiple publications to key scientific journals. Frequent venues for their work include:

  • Journal of Proteome Research
  • Analytical Chemistry
  • Zenodo (CERN European Organization for Nuclear Research)
  • Cardiovascular Diabetology
  • The Analyst

Their recent papers illustrate a focus on NMR spectroscopy and metabolomics in relation to COVID-19. Selected publications include:

  • Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome (2021), Journal of Proteome Research
  • NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines (2021), Journal of Proteome Research
  • Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection (2021), Analytical Chemistry
  • Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples (2020), Journal of Proteome Research
  • Integrative Modeling of Plasma Metabolic and Lipoprotein Biomarkers of SARS-CoV-2 Infection in Spanish and Australian COVID-19 Patient Cohorts (2021), Journal of Proteome Research

Manfred Spraul has frequently collaborated with several co-authors across their body of work, including:

  • Claire Cannet
  • Jeremy K. Nicholson
  • Elaine Holmes
  • Samantha Lodge
  • Hartmut Schäfer

Best Publications

  • 750 MHz 1H and 1H-13C NMR Spectroscopy of Human Blood Plasma

    J. K. Nicholson;P. J. D. Foxall;M. Spraul;R. D. Farrant

  • Cryogenically cooled probes—a leap in NMR technology

    Helena Kovacs;Detlef Moskau;Manfred Spraul

  • Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping

    Anthony C. Dona;Beatriz Jiménez;Hartmut Schäfer;Eberhard Humpfer

  • Chemometric models for toxicity classification based on NMR spectra of biofluids

    Elaine Holmes;Andrew W. Nicholls;John C. Lindon;Susan C. Connor

  • Molecular structures and associations of humic substances in the terrestrial environment

    André J. Simpson;William L. Kingery;Michael H. B. Hayes;Manfred Spraul

  • High‐resolution magic angle spinning MRS of breast cancer tissue

    Beathe Sitter;Beathe Sitter;Ursula Sonnewald;Manfred Spraul;Hans E. Fjösne

  • Summary recommendations for standardization and reporting of metabolic analyses.

    John C Lindon;Jeremy K Nicholson;Elaine Holmes;Hector C Keun

  • Development of a model for classification of toxin-induced lesions using 1H NMR spectroscopy of urine combined with pattern recognition.

    E. Holmes;A. W. Nicholls;J. C. Lindon;S. Ramos

  • Evidence of different metabolic phenotypes in humans

    Michael Assfalg;Ivano Bertini;Donato Colangiuli;Claudio Luchinat

  • Targeted and nontargeted wine analysis by (1)h NMR spectroscopy combined with multivariate statistical analysis. Differentiation of important parameters: grape variety, geographical origin, year of vintage.

    Rolf Godelmann;Fang Fang;Eberhard Humpfer;Birk Schütz

  • LC-NMR-MS in drug discovery

    Olivia Corcoran;Manfred Spraul

  • Automatic data reduction and pattern recognition methods for analysis of 1H nuclear magnetic resonance spectra of human urine from normal and pathological states.

    E. Holmes;P.J.D. Foxall;J.K. Nicholson;G.H. Neild

  • High-resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla.

    S. Garrod;E. Humpfer;M. Spraul;S.C. Connor

  • 750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease

    E. Holmes;P. J. D. Foxall;M. Spraul;R. D. Farrant

  • High-resolution 1H and 1H-13C magic angle spinning NMR spectroscopy of rat liver

    M.E. Bollard;S. Garrod;E. Holmes;J.C. Lindon

  • Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial.

    Beatriz Jiménez;Elaine Holmes;Clement Heude;Rose F. Tolson

  • Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties.

    Peter S Belton;Ian J Colquhoun;E.Katherine Kemsley;Ivonne Delgadillo

  • Separation and identification of phenolic compounds in olive oil by coupling high-performance liquid chromatography with postcolumn solid-phase extraction to nuclear magnetic resonance spectroscopy (LC-SPE-NMR).

    Unknown

  • Study of the compositional changes of mango during ripening by use of nuclear magnetic resonance spectroscopy.

    Ana M. Gil;Iola F. Duarte;Ivonne Delgadillo;Ian J. Colquhoun

  • High-Resolution Nuclear Magnetic Resonance Spectroscopy and Multivariate Analysis for the Characterization of Beer

    Iola Duarte;Antonio Barros;Peter S. Belton;Renton Righelato

  • Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy

    Detlef Moka;Roland Vorreuther;Harald Schicha;Manfred Spraul

Frequent Co-Authors

Jeremy K. Nicholson
Jeremy K. Nicholson Murdoch University
John C. Lindon
John C. Lindon Imperial College London
Elaine Holmes
Elaine Holmes Imperial College London
Ian D. Wilson
Ian D. Wilson Imperial College London
Ana M. Gil
Ana M. Gil University of Aveiro
Klaus Albert
Klaus Albert University of Tübingen
André J. Simpson
André J. Simpson University of Toronto
Peter S. Belton
Peter S. Belton University of East Anglia
Myrna J. Simpson
Myrna J. Simpson University of Toronto

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