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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
11057
World Ranking
16593
National Ranking
6867

Overview

Lorne M. Golub is affiliated with Stony Brook University in the United States and is recognized for contributions primarily in the field of Dentistry, with a focus on Periodontics. Their research encompasses subfields such as Molecular Medicine, Oral Surgery, Immunology, and Orthodontics.

The scientific output of Golub reveals a strong emphasis on oral microbiology and periodontitis research, evidenced by publications covering 26 works in this topic area. Additional main topics include Curcumin's biomedical applications, dental materials and restorations, oral health pathology and treatment, endodontics and root canal treatments, COVID-19 clinical research studies, and immune response and inflammation.

Golub has published research in several scholarly venues, frequently appearing in journals like Frontiers in Dental Medicine, Journal of Experimental Pharmacology, Journal of Inflammation Research, Expert Review of Proteomics, and Diagnostics.

Their recent notable publications include:

  • Active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) in the COVID-19 pandemic, 2021, Expert Review of Proteomics
  • Chemically-Modified Curcumin 2.24: A Novel Systemic Therapy for Natural Periodontitis in Dogs, 2020, Journal of Experimental Pharmacology
  • An Unexplored Pharmacologic/Diagnostic Strategy for Peri-Implantitis: A Protocol Proposal, 2020, Diagnostics
  • A Novel Modified-Curcumin Promotes Resolvin-Like Activity and Reduces Bone Loss in Diabetes-Induced Experimental Periodontitis, 2021, Journal of Inflammation Research
  • A novel modified-curcumin 2.24 resolves inflammation by promoting M2 macrophage polarization, 2023, Scientific Reports

Frequent collaborators in Golub's research include Francis Johnson, Hsi-Ming Lee, Ying Gu, Jie Deng, and Joseph Scaduto.

Best Publications

  • Tetracyclines Inhibit Connective Tissue Breakdown by Multiple Non-Antimicrobial Mechanisms

    L. M. Golub;H. M. Lee;M. E. Ryan;W. V. Giannobile

  • Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation.

    Timo Sorsa;Leo Tjäderhane;Yrjö T Konttinen;Anneli Lauhio

  • Tetracyclines inhibit connective tissue breakdown: new therapeutic implications for an old family of drugs.

    Lorne M. Golub;N.S. Ramamurthy;Thomas F. McNamara;Robert A. Greenwald

  • A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis

    L. M. Golub;H. M. Lee;R. A. Greenwald;M. E. Ryan

  • Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva

    Lorne M. Golub;Timo Sorsa;Hsi-Ming Lee;Sebastian Ciancio

  • Low-dose doxycycline therapy: effect on gingival and crevicular fluid collagenase activity in humans.

    L. M. Golub;S. Ciancio;N. S. Ramamurthy;M. Leung

  • Pharmacologic suppression of experimental abdominal aortic aneurysms : A comparison of doxycycline and four chemically modified tetracyclines

    John A. Curci;Drazen Petrinec;Shixiong Liao;Lorne M. Golub

  • Blocking Periodontal Disease Progression by Inhibiting Tissue-Destructive Enzymes: A Potential Therapeutic Role for Tetracyclines and Their Chemically-Modified Analogs.

    Barry R. Rifkin;Anthony T. Vernillo;Lorne M. Golub

  • Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model.

    Bal L. Lokeshwar;Marie G. Selzer;Bao Qian Zhu;Norman L. Block

  • Doxycycline and chemically modified tetracyclines inhibit gelatinase A (MMP-2) gene expression in human skin keratinocytes

    Veli-Jukka Uitto;James D. Firth;Leslie Nip;Lorne M. Golub

  • Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis.

    R. E. B. Seftor;E. A. Seftor;J. E. De Larco;D. E. Kleiner

  • Scientific basis of a matrix metalloproteinase-8 specific chair-side test for monitoring periodontal and peri-implant health and disease.

    Timo Sorsa;Päivi Mäntylä;Hanne Rönkä;Pekka Kallio

  • Subantimicrobial Dose Doxycycline Efficacy as a Matrix Metalloproteinase Inhibitor in Chronic Periodontitis Patients Is Enhanced When Combined With a Non-Steroidal Anti-Inflammatory Drug

    Hsi Ming Lee;Sebastian G. Ciancio;Gülay Tüter;Maria E. Ryan

  • Can Systemic Diseases Co-induce (Not Just Exacerbate) Periodontitis? A Hypothetical “Two-hit” Model

    L.M. Golub;J.B. Payne;R.A. Reinhardt;G. Nieman

  • Some Characteristics of Collagenase Activity in Gingival Crevicular Fluid and Its Relationship to Gingival Diseases in Humans

    Lorne M. Golub;Kenneth Siegel;N.S. Ramamurthy;Irwin D. Mandel

  • Matrix metalloproteinase inhibitor prevents acute lung injury after cardiopulmonary bypass.

    David E. Carney;Charles J. Lutz;Anthony L. Picone;Louis A. Gatto

  • Method for inhibiting expression of inducible nitric oxide synthase with tetracycline

    Ashok R. Amin;Steven B. Abramson;Lorne M. Golub;Nungavaram S. Ramamurthy

  • Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy

    Maria Emanuel Ryan;Lorne M. Golub

  • Periodontal therapeutics: Current host-modulation agents and future directions.

    Lorne M. Golub;Hsi‐Ming Lee

  • Inhibition of Matrix Metalloproteinase-Mediated Periodontal Bone Loss in Rats: A Comparison of 6 Chemically Modified Tetracyclines

    Nungavarum S Ramamurthy;Barry R Rifkin;Robert A Greenwald;Jing-Wen Xu

Frequent Co-Authors

Timo Sorsa
Timo Sorsa University of Helsinki
Francis Johnson
Francis Johnson Stony Brook University
Tuula Salo
Tuula Salo University of Helsinki
Christopher T. Ritchlin
Christopher T. Ritchlin University of Rochester Medical Center
Petri T. Kovanen
Petri T. Kovanen Wihuri Research Institute
Yrjö T. Konttinen
Yrjö T. Konttinen Helsinki University Hospital
Stanley Zucker
Stanley Zucker Stony Brook University
Yoram Vodovotz
Yoram Vodovotz University of Pittsburgh
Michael Glogauer
Michael Glogauer University of Toronto
Robert J. Genco
Robert J. Genco University at Buffalo, State University of New York

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