Juergen Loeffler

Best Publications

• Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5,6-desaturation

  S.L Kelly;D.C Lamb;D.E Kelly;N.J Manning

  460
  Citations

• Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis.

  Carlo Mengoli;Mario Cruciani;Rosemary Ann Barnes;Juergen Loeffler

  431
  Citations

• Quantification of Fungal DNA by Using Fluorescence Resonance Energy Transfer and the Light Cycler System

  Juergen Loeffler;Norbert Henke;Holger Hebart;Diethard Schmidt

  419
  Citations

• Aspergillus PCR: One Step Closer to Standardization

  P.L. White;S. Bretagne;L. Klingspor;W.J.G. Melchers

  353
  Citations

• The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model.

  Franziska Lessing;Franziska Lessing;Olaf Kniemeyer;Olaf Kniemeyer;Iwona Wozniok;Juergen Loeffler

  303
  Citations

• Aspergillus fumigatus antigens activate innate immune cells via toll-like receptors 2 and 4.

  Sibylla Braedel;Markus Radsak;Hermann Einsele;Jean-Paul Latgé

  255
  Citations

• Contaminations Occurring in Fungal PCR Assays

  Juergen Loeffler;Holger Hebart;Ralf Bialek;Lars Hagmeyer

  230
  Citations

• Evaluation of Aspergillus PCR Protocols for Testing Serum Specimens

  P. Lewis White;Carlo Mengoli;Stephane Bretagne;Manual Cuenca-Estrella

  181
  Citations

• Resistance to fluconazole and amphotericin in Candida albicans from AIDS patients

  Steven L Kelly;David C Lamb;Diane E Kelly;Juergen Loeffler

  178
  Citations

• Nucleic acid sequence-based amplification of Aspergillus RNA in blood samples.

  Juergen Loeffler;Holger Hebart;Philipp Cox;Nicole Flues

  176
  Citations

• The G464S amino acid substitution in Candida albicans sterol 14alpha-demethylase causes fluconazole resistance in the clinic through reduced affinity

  Steven L. Kelly;David C. Lamb;Juergen Loeffler;Herman Einsele

  163
  Citations

• Cross-protective TH1 immunity against Aspergillus fumigatus and Candida albicans

  Claudia Stuehler;Nina Khanna;Silvia Bozza;Teresa Zelante

  162
  Citations

• A prospective randomized controlled trial comparing PCR-based and empirical treatment with liposomal amphotericin B in patients after allo-SCT

  H Hebart;L Klingspor;T Klingebiel;J Loeffler

  159
  Citations

• Comparison between plasma and whole blood specimens for detection of Aspergillus DNA by PCR.

  Juergen Loeffler;Holger Hebart;Ulrike Brauchle;Ulrike Schumacher

  156
  Citations

• Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-γ release.

  Maria Bouzani;Michael Ok;Allison McCormick;Frank Ebel

  150
  Citations

• Clinical Performance of Aspergillus PCR for Testing Serum and Plasma: a Study by the European Aspergillus PCR Initiative

  P. Lewis White;Rosemary Ann Barnes;Jan Springer;Lena Klingspor

  150
  Citations

• Polymorphisms in the chemokine (C-X-C motif) ligand 10 are associated with invasive aspergillosis after allogeneic stem-cell transplantation and influence CXCL10 epression in monocyte-derived dendritic cells

  Markus Mezger;Michael Steffens;Melanie Beyer;Carolin Manger

  140
  Citations

• Automated Extraction of Genomic DNA from Medically Important Yeast Species and Filamentous Fungi by Using the MagNA Pure LC System

  Juergen Loeffler;Kathrin Schmidt;Holger Hebart;Ulrike Schumacher

  139
  Citations

• Molecular Detection and Identification of Zygomycetes Species from Paraffin-Embedded Tissues in a Murine Model of Disseminated Zygomycosis: a Collaborative European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG) Evaluation

  Eric Dannaoui;Patrick Schwarz;Michal Slany;Juergen Loeffler

  129
  Citations

• Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells

  Nikolaus Rieber;Anurag Singh;Hasan Öz;Melanie Carevic

  128
  Citations