His primary areas of study are Genetics, Anatomy, Neuroscience, Hox gene and Gene. In most of his Genetics studies, his work intersects topics such as Cell biology. His Anatomy research incorporates themes from Olfaction, Tomography, Optical projection tomography and Optogenetics.
His study in Hox gene is interdisciplinary in nature, drawing from both Reprogramming, Hindbrain and Transgene. James Sharpe works on Gene which deals in particular with Body Patterning. His Phenotype research is multidisciplinary, incorporating perspectives in Evolutionary biology, Endoskeleton, Mesenchyme and Period.
James Sharpe mainly focuses on Cell biology, Genetics, Anatomy, Computational biology and Gene regulatory network. The various areas that James Sharpe examines in his Cell biology study include T cell, Cytotoxic T cell, CD8 and In vivo. All of his Genetics and Phenotype, Limb development, Hox gene, Body Patterning and Fibroblast growth factor investigations are sub-components of the entire Genetics study.
His Phenotype research includes themes of Mutation and Evolutionary biology. The concepts of his Anatomy study are interwoven with issues in Limb bud, Tomography, Optical projection tomography and Morphogenesis. His Gene regulatory network research includes elements of Morphogen and Theoretical computer science.
His primary areas of investigation include Cell biology, Mutation, Gene regulatory network, Computational biology and DNA sequencing. His Cell biology research is multidisciplinary, incorporating elements of Cytotoxic T cell, Morphogenesis, CD8 and T cell. Many of his studies on Mutation apply to Phenotype as well.
In general Phenotype, his work in Genetic imbalance is often linked to Egcg treatment linking many areas of study. His Gene regulatory network study contributes to a more complete understanding of Gene. His research in Systems biology tackles topics such as Variation which are related to areas like Genetics and Synthetic gene.
James Sharpe mainly focuses on Cytotoxic T cell, Cell biology, CD8, T cell and Chemistry. The Cytotoxic T cell study combines topics in areas such as Chemotaxis, Chemokine, Motility, Salivary gland and Cell type. James Sharpe works in the field of Cell biology, focusing on Epidermis in particular.
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Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies
James Sharpe;Ulf Ahlgren;Paul Perry;Bill Hill.
Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer;Alba Mas;Alexandre Robert-Moreno;Matteo Pecoraro.
Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients
J. Raspopovic;L. Marcon;L. Russo;J. Sharpe;J. Sharpe.
Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism
Rushikesh Sheth;Luciano Marcon;Luciano Marcon;M. Félix Bastida;M. Félix Bastida;Marisa Junco.
Positional information and reaction-diffusion: two big ideas in developmental biology combine.
Jeremy B. A. Green;James Sharpe.
Optical projection tomography
James Alexander Sharpe.
Annual Review of Biomedical Engineering (2003)
Reprogramming Hox Expression in the Vertebrate Hindbrain: Influence of Paraxial Mesoderm and Rhombomere Transposition
Nobue Itasaki;James Sharpe;Alastair Morrison;Robb Krumlauf.
Tomographic molecular imaging and 3D quantification within adult mouse organs.
Tomas Alanentalo;Amir Asayesh;Harris Morrison;Christina E Lorén.
Nature Methods (2007)
Optical projection tomography as a new tool for studying embryo anatomy
Journal of Anatomy (2003)
EMAP and EMAGE: a framework for understanding spatially organized data.
Richard A. Baldock;Jonathan Bard;Jonathan Bard;Albert Burger;Nicholas Burton.
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